Sentences with phrase «sequencing methods»

Then about five years ago, next - generation sequencing methods became available.

As a result, the reconstruction of whole parasite genome DNA sequences is slow, expensive and error - prone using current DNA sequencing methods.

The historical sequence method consists of running a portfolio against actual historical sequences of investment returns.

His lab is interested in leveraging new sequencing methods and technologies to understand the physical genome.

I am also developing various imaging and molecular sequencing methods for tracking genes, molecules, and cells to understand how cancer cells arise and evolve.

Modern genome sequencing methods make it relatively easy to read the individual «letters» in DNA, but only in short fragments.

To determine expression levels, in traditional sequencing methods a mix of millions of cells is used.

The historical sequence method revealed the vulnerability of approaches that include selling shares.

For example, because individual cells in the tumor probably carry unique mutations, they would be virtually impossible to observe with standard sequencing methods.

Conventional shotgun sequencing methods can only be used for fairly short strands of DNA.

The historical sequence method also allows you to vary stock allocations in accordance with valuations.

After that, it proceeds very much as with the historical sequence method.

Traditional sequencing methods can capture only a fraction of the millions of antibodies circulating in the bloodstream at a given time.

Background: Nanopore sequencing is a third generation genomic sequencing method that offers real time sequencing of DNA samples.

The study, «Analysis of DNA from post-blast pipe bomb fragments for identification and determination of ancestry,» examined different collection and extraction methods for degraded and small samples of DNA left behind on detonated pipe bombs, including short tandem repeat markers (SNPs), single nucleotides polymorphisms via a new sequencing method called massively parallel sequencing or MPS, and insertion / null (INNULs).

A visual 13 slide presentation which runs through the Sanger sequencing method in a fully animated comprehensive manner.

In order to address this question, the team lead by the Freiburg pharmacologists used modern sequencing methods.

Nanopore sequencing promises to do away with these added steps by sequencing single unmodified DNA strands, and thereby possibly becoming the fastest and cheapest sequencing method on the market.

On a similar note, the latest single cell sequencing methods based on stochastic schemes for in situ barcoding of cells are impossible to assess with negative control samples.

«That is why we have followed the composition of the intestinal microbiota of patients using modern DNA sequencing methods over a period of up to three months after treatment.»

Last year Broad researchers described a single - nucleus RNA sequencing method called sNuc - Seq.

The study, funded in part by the Pancreatic Cancer Action Network and The National Pancreas Foundation, also was the first to evaluate a test that employed a more sensitive genetic sequencing method called next - generation sequencing and the first to be performed in a certified and accredited clinical laboratory as opposed to a research setting.

By using new gene sequencing methods, a team led by Thomas Givnish, a plant ecologist at the University of Wisconsin, Madison, created a phylogeny of orchids with an unprecedented 75 chloroplast genes from 39 species, representing almost all major groups of orchids, as well as from 96 distant relatives among all flowering plants.

The new deep sequencing methods allow data to be acquired much more efficiently and inexpensively, but optimal methods are less well developed (for some recent work in this area see [8, 14, 26]-RRB-.

Genome sequencing methods show perhaps the most dramatic effects.

U.S. Army Medical Research Institute of Infectious Diseases Viral Genomics Center, Frederick • MD 2009 — 2010 Microbiologist Collaborative part of multi-disciplinary team within highly - integrated environment to develop, optimize, characterize, and validate assays and sequencing methods in support of research projects aimed to identify threat agents and to evaluate efficacy and safety of vaccines and anti-viral therapies.

Scientists investigating the earliest stages of cancer development used an exquisitely sensitive sequencing method capable of detecting DNA mutations present in as few as 1.6 per cent of blood cells, to analyse 15 locations in the genome, which are known to be altered in leukemia.

For this purpose, the scientists combined a sophisticated bioinformatics strategy developed by Masaomi Hatakeyama that uses state - of - the - art sequencing methods with a new technology that can optically map the long, individual DNA molecules in the genome.

A new high - coverage DNA sequencing method reconstructs the full genome of Denisovans — relatives to both Neandertals and humans — from genetic fragments in a single finger bone

Recently, cultivation - independent sequencing methods have produced a wealth of genomic data for previously unidentified archaeal lineages, several of which appear to represent newly revealed branches in the tree of life.

To set the sequence straight, the lab turned to the unique sequencing method Page had developed with collaborators at Washington University in St. Louis to help navigate the structural complexities of the Y chromosome.

«Fortunately, these genetic checks can be readily performed with precise, sensitive, and increasingly inexpensive sequencing methods.»

And they figured they could read the address using methods akin to next - generation DNA sequencing, a set of high - speed genome sequencing methods Church helped develop in the early 2000s.

«Usually that would require extensive genetic analysis with complex sequencing methods, but our methodology achieves that goal quickly and with minimal experimental effort.»

Then, soon after the turn of the century, new high - octane DNA sequencing methods made it possible to sequence thousands or even millions of genes almost instantly.

Meanwhile, Jill Banfield of the University of California, Berkeley, and her colleagues used similar sequencing methods to stitch together the genomes of microbes in highly acidic water from an abandoned California gold mine.

But a study published today in the journal Scientific Reports reveals that a favored sequencing method for measuring microbial biodiversity is not as accurate as once thought.

Deeper understanding — and new medical treatments — requires many more sequenced genomes, as well as cheaper and faster sequencing methods.

As genomic sequencing methods continue to identify large numbers of novel cancer mutations, how can we identify the mutations in a given tumor that are most critical to the maintenance of its oncogenic phenotype?

-- Combining the detailed information from existing single cell analysis with our in situ sequencing method can be powerful and find great use in both research and diagnostics, says Mats Nilsson.

DNA samples are prepared from microbial specimens, and then analyzed using massively parallel sequencing methods such as 454 / Roche pyrosequencing [20].

One question in analyzing microbial communities by 16S rRNA gene pyrosequencing centers on whether the amplification and sequencing methods result in recovery of sequences in proportion to their representation in the original community [24].

New deep sequencing methods provide a convenient platform for characterizing the composition of the human microbiota [4, 7, 8, 13, 15 — 19].

Sanger sequencing methods represent the most popular in a range of «first - generation» nucleic acid sequencing technologies.

Including pre-processing and stringent data filtering as well as comparing different sequencing methods, eight editing candidates were identified.

Yet, SVs remain overlooked in human genetic research studies due to the limited power of short - read sequencing methods (exome and whole genome sequencing) to resolve large variants, which often involve repetitive DNA.

In the 1990s, the thought of sequencing the whole human genome presented a tremendous scientific challenge: The human genome contains more than 3 billion letters, and DNA sequencing methods at that time were slow and expensive.