Sentences with phrase «small molecule compounds»

The emerging field of DNA - encoded chemical library allows us to perform selection of small molecule compounds.
The partnership will give Swedish academic researchers access to AstraZeneca's annotated small molecule compound library with the aim of identifying novel protein targets aligned to key unmet medical needs.
Such assays enable researchers to identify small molecule compounds which interact with a target protein of interest.
The work follows a 2015 study that examined how specific small molecule compounds called «metabolites» were transformed in a mixture of bacterial isolates from biocrust samples cultured in a milieu of metabolites from the same soil.
In melanoma, the MAPK and PI3K pathways are primary targets for therapy, but other pathways are also explored for inhibition by small molecule compounds.
The Alzheimer's Innovation Award will help advance particularly critical components of Mucke's ongoing drug discovery program to identify and optimize small molecule compounds that potently and safely reduce tau levels in the brain.
For example, virtually every Pharmaceutical company's medicinal chemistry department now utilises NMR as a tool to verify the structure of small molecule compounds.
In this study, the researchers screened a library of 200,000 small molecule compounds to identify potential inhibitors of Ebola virus RNA synthesis.
«In fact, Dr. Gan and her team have already identified a small molecule compound that eliminates toxic p - tau in neurons.
However, this study tells us that if there is any way we can enhance inhibitory neuron function in the hippocampus, like through the development of small molecule compounds, it may be beneficial for Alzheimer disease patients.»
Reykjavik, ICELAND, November 17, 2003 — deCODE genetics (Nasdaq: DCGN) today announced that it has acquired an exclusive worldwide license from Bayer AG to develop and commercialize a small molecule compound.
The team screened a small molecule compound library and identify a drug, which they call CLP257.
In the field of life sciences, he has successfully litigated major cases involving recombinant DNA, monoclonal antibodies, fusion proteins, siRNAs, small molecule compounds, drug delivery, molecular diagnostics, research tool patents, and medical devices.
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