Sentences with phrase «therapeutic implications»

All this means severe distress for women and therapeutic implications for clinicians.

«I think it represents one of the most exciting findings in epilepsy research in the past year, with substantial therapeutic implications,» he says.

Imai and Stein pointed out possible therapeutic implications of this finding, especially in light of what is known about cognitive decline in aging and certain diseases.

The findings, published in the September issue of the journal Nature, show that targeting KSR could have important therapeutic implications, potentially improving outcomes in many aggressing cancers such as lung and pancreatic cancer.

In this review, dates fruits has medicinal value are summarized in terms of therapeutic implications in the various types of diseases through anti-oxidant, anti-cancerous and ant - diabetic character.

Regarding possible therapeutic implications, the researchers suggest that «augmenting Ly6C - negative monocyte accumulation or functionality may represent a useful intervention strategy complementing anti-infective medication in conditions of liver injury due to chronic infections.»

«This has broad therapeutic implications as well,» says Lindquist, who also is a professor of biology at MIT.

Replenishment of a-Klotho by either recombinant protein injection or drugs that increase a patient's own a-Klotho will have potential therapeutic implications for neurologic, metabolic, cardiovascular and kidney disease, and cancer.»

The findings in our study have immense therapeutic implications as they will be applicable not only to diabetes in obesity, but also to diabetes as a whole,» Dr Tergaonkar added.

The findings, being presented as part of a poster presentation at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Philadelphia, could have therapeutic implications specific to this rare form of the disease, say the authors.

Because telomere length influences premature aging and cancer, Yildiz's findings bear long - term therapeutic implications.

«The specific macromolecular complex investigated in this study has therapeutic implications not only for addiction, but also for Parkinson's disease and schizophrenia,» said Dr. Sergi Ferré, who led the team of scientists.

While there are no direct therapeutic implications for patient care based on the research, the authors note that future studies could indicate whether techniques that could stimulate the areas with decreased connectivity could be helpful to treat visual hallucinations in people with Parkinson's disease.

Yet, for Kaileh, the most rewarding aspect of her research has been engaging in biomedical work that could have real therapeutic implications.

«This concept has significant therapeutic implications and will drive the development of new therapies because it implies that MS will produce significant disability if suffered for enough time in all patients,» says co-author Dr. Pablo Villoslada, Head of the IDIBAPS research group in Pathogenesis and new treatments in multiple sclerosis and coordinator of the study.

Azevedo - Pereira JM, Santos - Costa Q. [Chemokine receptors and its importance in the replication cycle of human immunodeficiency virus: clinical and therapeutic implications].

Extending those findings, his team proved that diet - induced changes in gut microbial composition — and the attendant effects on weight and obesity — can be artificially transmitted between mice, raising therapeutic implications for people with metabolic disorders.

«The ability to reprogram fibroblasts into cardiomyocytes has many therapeutic implications,» explained Dr. Srivastava, senior author on the paper.

These findings have therapeutic implications since inhibiting MBD2 could offer a strategy to reactivate BAI1 and suppress glioma pathobiology, â $ the authors write.

Pal L, Berry A, Coraluzzi L, Kustan E, Danton C, Shaw J, Taylor H Therapeutic Implications of vitamin D and calcium in overweight women with polycystic ovary syndrome..

Vitamin D deficiency is highly prevalent in patients with IBS and these results seem to have therapeutic implications >

Goulb LM, et al: Tetracyclines imibit comective tissue breakdown: new therapeutic implications for an old family of drugs.

Review Stressed Out - Therapeutic Implications of ER Stress Related Cancer Research Randal Riha, Pooja Gupta - Saraf, Payel Bhanja, Samyak Badkul, Subhrajit Saha Oncomedicine 2017; 2: 156 - 167.

This has important therapeutic implications, as surgical repair will not be able to address the cellular muscle defect in HLHS patients, noted Lo.

Because traffic of molecules between the nucleus and the cytoplasm of nerve cells is altered in several other neurodegenerative disorders, targeting nuclear transport may have broader therapeutic implications in diseases like amyotrophic lateral sclerosis (ALS) and Alzheimer's disease.

With potential therapeutic implications, Stainier and a colleague also recently discovered that endothelial cells, which line the blood vessels, play a critical role in inducing the development, or proper differentiation, of red blood cells, the transporters of oxygen.

The findings, being presented as part of a poster presentation at the Annual Meeting of the American Association for Cancer Research (AACR) being held in Philadelphia this week, could have therapeutic implications specific to this rare form of the disease, say the authors.

The discovery of 6 - OH - dopa has therapeutic implications for more than just breast and ovarian cancer — the diseases most widely associated with BRCA mutations.

As far as the study's therapeutic implications, one thing seems clear: If new drugs are to target ApoE in the brain, they should bring its levels down, not up.

The therapeutic implications of the findings are far - reaching.

Adds Matt Kaeberlein, a biologist who studies aging at the University of Washington, Seattle, «The therapeutic implications are profound if this mechanism holds true in people.»

«Next, we will explore the therapeutic implications of our discovery by repurposing available drugs that block these adenosine receptors and are well tolerated in humans.»

The question of whether people can harbor more than one character has important legal and therapeutic implications.

«If we establish a link between circadian mechanisms and type 2 diabetes via lipid metabolism, this could have important therapeutic implications.

«Taken together, these findings provide evidence for differential neural plasticity across different ages, with potential prognostic and therapeutic implications,» said the study's co-author, Ying - Chi Tseng, M.D., from Shuang - Ho Hospital.

By revealing patterns in the development of the microbiome in healthy individuals, and in those progressing toward T1D onset, the findings may ultimately have diagnostic or therapeutic implications.

We suggest these observations will have therapeutic implications for skeletal myopathies and systemic diseases such as diabetes and obesity and for the aged population, in which reduced endurance impacts mortality and activities of daily living (57); as well as societal implications in terms of altering athletic performance.

This finding has therapeutic implications, particularly since drugs exist to control PKA.

Thus, we are identifying molecular and circuit mechanisms of brain dysfunction and exploring the therapeutic implications of enhancing inhibitory functions and / or restoring oscillatory rhythms in brain disorders associated with abnormal synchronization of neuronal networks, such as AD, schizophrenia, autism, or epilepsy.

Consider the therapeutic implications of emerging data on evolving treatment paradigms for patients with hematologic tumors

The discovery is a window onto communication between the muscle and brain, which may have therapeutic implications, say Hyo Youl Moon and Henriette van Praag of the National Institute on Aging in a commentary about the new work published in Cell Metabolism.

And what are the therapeutic implications of such findings in aging people not exposed to this neurotoxin?

Pursuing the therapeutic implications of that possibility, Hur has teamed up with a pharmaceutical firm to find drugs that can suppress aberrant signaling by MDA5.

Diverse cellular functions and therapeutic implications of Poly (ADP - ribose) family members: promising targets in cancer therapy

Kato T. Mitochondrial dysfunction as the molecular basis of bipolar disorder: therapeutic implications.