Sentences with phrase «to regulate cell growth»

Vitamin D - 3 also plays an important role in regulating cell growth, insulin levels, and bone formation.

It interacts with an enzyme in the human body that helps regulate cell growth and control immune response.

It triggers the action of enzymes and is an important component of proteins responsible for regulating cell growth, reproduction and death.

Previously described as the «guardian of the genome» and voted «Molecule of the Year» in 1993, p53 is one of the most important proteins regulating cell growth and a major focus for oncology research.

We study the signal transduction pathways regulating cell growth and proliferation, with an emphasis on kinase enzymes.

BRCA1 regulates cell growth in the breast's milk ducts.

Zochodne and his team decided to look for Rb in nerve cells because of its known role in regulating cell growth elsewhere in the body.

Proteasomes play an important role in the degradation of proteins that regulate the cell cycle, thereby regulating cell growth.

The protein mTOR regulates cell growth and metabolism and thus plays a key role in the development of human disorders.

-- A fundamental question in biology is how multicellular organisms regulate their cell growth.

Iron is essential for life as it transports oxygen in your body, helps regulate cell growth, maintains brain function, metabolism and endocrine function and is involved in energy production and immune function

«Interleukins have important roles in regulating cell growth, cell death and in the activation of the immune system,» explained Matthew Schabath, Ph.D., assistant member of the Cancer Epidemiology Program at Moffitt.

So Hoffman is now looking for leads among genes controlling the production of molecules called growth factors, which regulate cell growth and division.

The pathway regulates cell growth, death and other functions that are often disrupted in cancer, but it's role in medulloblastoma is poorly understood.

Their findings provide new insights into how the protein regulates cell growth and how mutations in the gene that encodes the protein can lead to cancer.

Hydrolyzed Collagen is the missing link in supplying amino acids like glycine, proline and lysine that are required by the body to build connective tissue to regulate cell growth.

They cross the blood - brain / blood - tumor barrier, and accumulate within brain tumor sites, where they target oncogenes, regulate cell growth and differentiation, reduce tumor burden and prolong survival in our mouse models.»

Take the ras gene known as KRAS, for example: It produces a critical protein, also called KRAS, that regulates cell growth and appropriate cell aging, known as senescence.

In cancer, these switches inappropriately activate or silence important genes, such as those that regulate cell growth and life cycle, ultimately leading to tumors.

Neuroscientists already knew that a signaling protein called mTORC1 that regulates cell growth and metabolism plays a major role in HD.

P53 is a tumor suppressor gene, a protein that regulates cell growth, and it is the most frequently mutated suppressor gene in cancer.

In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.

Jasper says researchers at the Buck are also testing homologues of rapamycin that are more specifically aimed at TOR Complex 1 — a key complex containing TOR that regulates cell growth and metabolism in all complex organisms.

Once the gene breaks from its natural moorings, it loses its usual ability to regulate cell growth in the lungs.

All of the known mechanisms driving adenocarcinoma in the lungs (more than eight have been discovered to date) are powered by kinase genes like ALK which, when healthy, regulate cell growth.

Most group 3 medulloblastoma tumors feature excessive levels of the c - MYC protein, which helps to regulate cell growth.

To understand how cells multiply out of control and form tumors, scientists have long focused on proteins that regulate cell growth.

As a result, they can more efficiently interact with the cell membrane, regulate cell growth and suppress tumor formation.

mTOR - raptor complex is sensitive to rapamycin and regulates cell growth, in part, by phosphorylation of p70S6K and subsequently rpS6 and 4E - BP1, thus promoting protein translation.

The researchers also showed that Timp - 1, a gene involved in regulating cell growth, carries orders from NF - KB to tell lung cancer cells to proliferate.

mTOR - raptor complex (composed of mTOR, raptor, and GβL) is sensitive to rapamycin and regulates cell growth, in part, by phosphorylation of the ribosomal protein S6 (rpS6) kinase (p70S6K or S6K1) and subsequent phosphorylation of rpS6 to stimulate protein translation and ribosome biogenesis (9, 10).

SHP2, encoded by the PTPN11 gene, links growth factor signaling with the downstream RAS / ERK / MAPK pathway to regulate cell growth and division.

These genes provide instructions on how to regulate cell growth, death, and division as well as how fix mistakes in the DNA.

Hydrolyzed Collagen is the missing link in supplying amino acids like glycine, proline and lysine that are required by the body to build connective tissue to regulate cell growth.

The main function of growth hormone is to regulate cell growth and regeneration in all tissues, including muscles and bones.

Iron is contained in numerous proteins and enzymes, and it is shown to transport oxygen to regulate cell growth.

As we have mentioned in the introduction, riboflavin does a nice job to regulate cell growth and reproduction.

mTOR is a biological pathway in the body which plays an important role in regulating cell growth and proliferation that may also have an influence over cancer growth (6).

Zinc is an essential component in a number of enzymes that help in regulating cell growth, protein synthesis, hormonal level, DNA, regulating gene transcription, energy metabolism, and other related functions.

The first trial will evaluate Rapamycin, also known as Sirolimus, a promising cancer treatment drug that targets a protein that regulates cell growth.