Vasculature refers to the network of blood vessels, including arteries, veins, and capillaries, that transport blood throughout the body. It is like a highway system that delivers oxygen, nutrients, and waste products to various tissues and organs in the body.
Full definition
A remarkable live image of perfused
vasculature in a mouse brain reveals a glioblastoma, a fast growing tumor, in rendered in green.
The target molecule of the immunization strategy is the extra domain - A (ED - A) of fibronectin, a protein domain which is highly selective for the
tumor vasculature in the adult.
If there is evidence of cardiomegaly / remodeling on the ECHO, then radiographs are also suggested to measure VHS, evaluate the cardiac chambers subjectively, and obtain a «baseline» for the appearance of
pulmonary vasculature and parenchyma.
Bioprinting technique creates thick 3D tissues composed of human stem cells with embedded
vasculature with potential for drug testing and regenerative medicine
With the ability to become all of the blood cells — including your immune cells, red blood cells, all of your blood system, as well
as vasculature — hemangioblasts have been biology's holy grail.
The characteristic scarring and loss of
lung vasculature was slowed in every mouse, and the lung tissue of some mice began to return to normal.
After two weeks, the team was surprised to find that blood vessels riddled the tissue, linking it to the mouse
vasculature system.
Interestingly, the histamine molecule along with the amino acids tyrosine and arginine all have an effect
on vasculature (blood flow), and have been linked to contribute to migraine headaches.
This is a human iPS cell - derived glomerulus that is connected to the
mouse vasculature upon transplantation.
(d) Representative images of the tumour
vasculature stained for CD31 and NG2 in tumours grown in WT and Tie2PEKO mice.
Introducing a dye into the bloodstream then allowed her to image the
growing vasculature around the islets.
The lenses
enhance vasculature beneath skin, helping nurses identify veins; they also amplify trauma and bruising that might be invisible to the naked eye.
Collectively, the experiments identified a more angiogenic and leaky, yet well
perfused vasculature in tumours of mice with targeted deletion of Tie2 in pericytes.
A patient's own bone marrow stem cells can form bone and cartilaginous tissue, not the
underlying vasculature and nerve compartments; and, embryonic stem cell derived bone may prompt an immune rejection.
Lewis has previously conducted groundbreaking research in the 3 - D printing of functional materials, including tissue constructs with
embedded vasculature, lithium - ion microbatteries, and ultra-lightweight carbon - fiber epoxy materials.
The number of leukocytes (arrows) in the
inflamed vasculature was significantly reduced in the RNAi - treated retina (right) comparing to the control experiment (left).
By pumping bone growth factors through the supporting
vasculature lined with the same endothelial cells found in our blood vessels, the team induced cell development toward bone cells over the course of one month.
We showed that the EphA2 receptor is upregulated in the tumor
vasculature together with the ephrin - A1 ligand, which suggested a role in tumor angiogenesis that is now well established.
If the regression of the temporary blood vessels does not take place, defects arise in the eye, leading to the uncommon but severe disease persistent
foetal vasculature syndrome, PFVS.
The strategy of the devices» transport mechanism is both simple and ingenious, i.e., the scientists put commercially - available, biocompatible magnetic particles into an
artificial vasculature.
«If the aorta is stiff, then when it transfers the pulse energy all the way to the
peripheral vasculature — to small vessels — it can cause end organ damage.
«We will be able to use your data points,» Kuhn explains, «to
compare vasculature, cortical thickness, functional networks, etc., across the entire group as a function of age.»
When the heart beats, it generates a waveform, and with a healthy heart and
vasculature there are fewer and smaller waves.
When replacing the
islet vasculature in aged islet grafts with young capillaries, the investigators found that the islets were rejuvenated and glucose homeostasis fully restored.
Surprisingly, drugs meant to
destroy vasculature can make the repairs and may help reverse conditions that lead to cardiovascular disease and blindness
Then structures and characteristics were identified by humans and algorithms before they were computed into three - dimensional, color -
coded vasculature and cell bodies.
As part of the new study, researchers deleted CXCL12 production specifically from bone
marrow vasculature in leukemic mice.
«It behaves just
like vasculature, and around it there is a lattice for other cells to attach and grow.»
To demonstrate the precision of the technique and its ability to generalize to many different human tissue types, the research team created several proof - of - principle organoid arrays mimicking human tissues such as
branching vasculature and mammary glands.
More than most people's, Cox's
vasculature responds to the cold by limiting how much warm, core - temperature blood gets sent to the extremities, where it would cool more rapidly.
«We could potentially template that
vasculature using alginate and then dissolve it away like we did for the microfluidic channels.»
The placenta's
complex vasculature (blue) sustains a growing fetus through its umbilical cord (white).
«In addition, the disrupted,
leaky vasculature that develops in and around tumors — what we call the blood tumor barrier — allows some accumulation of anti-HER2 and anti-PI3K drugs in brain metastases.
The data show that chronic prenatal hypoxia, leading to a significant increase in fetal haematocrit, promotes fetal aortic wall thickening and oxidative stress in the fetal heart and
vasculature by the end of gestation.
«The ability to form functional vascular networks in 3D tissues before they are implanted not only enables thicker tissues to be formed, it also raises the possibility of surgically connecting these networks to the
natural vasculature to promote immediate perfusion of the implanted tissue, which should greatly increase their engraftment and survival.»
In turn, tumour angiogenesis is characterized by a pathological patency of the angiogenic stimulus resulting in a chaotropic, pro-angiogenic and permanently
immature vasculature.
Phrases with «vasculature»