Sentences with phrase «vesicle trafficking»
Vesicle trafficking means the movement of tiny sacs called vesicles inside cells. These vesicles carry important substances like proteins and molecules from one part of the cell to another. This process helps maintain the cell's structure, transports materials, and enables communication between different parts of the cell. It's like a delivery service within cells that ensures everything is in the right place and functioning properly. Full definition
CTL1 mutation also altered the distribution of ion transporters, which, combined with previous work localizing CTL1 to the trans - Golgi network, led the authors to investigate whether CTL1 played a direct role in vesicle trafficking.
sciencedaily.com
He has been a leader in investigation of the roles of specific roles of Rab small GTPases and their effectors in regulating vesicle trafficking, membrane recycling and polarity in polarized cells.
And not only cancer: «Tyrosine phosphorylation is now known to be involved in a large number of absolutely crucial cellular functions from normal cell growth to intracellular vesicle trafficking to immune responses.
«A new regulator of vesicle trafficking in plants: Choline transporter regulates ion homeostasis and plant growth and development.»
«A «pause button» for cells: Optogenetic system inhibits intracellular membrane vesicle trafficking.»
He is presently studying the role of specific defects in apical vesicle trafficking in the etiology of neonatal diarrhea syndromes in human.
In her research she uses C. elegans and mammalian cells to study dense core vesicle trafficking and Gq signaling in neurons.
Vesicle Traffic Late in the Secretory Pathway Little is known about the mechanism of sorting and packaging of secretory proteins that transit from the Golgi complex to the cell surface.
Others including Randy Schekman had discovered NSF to be important for vesicle trafficking and secretion in yeast, leading Rothman to argue that these proteins are involved in vesicle fusion in every cell of the animal kingdom — a universal mechanism for secretion.
A protein that transports the simple chemical choline plays a major role in vesicle trafficking, ion homeostasis, and growth and development in plants, according to two new studies publishing 28 December in the open - access journal PLOS Biology, by Dai - Yin Chao of the Shanghai Institutes for Biological Sciences, China, and Sheng Luan of the University of California, Berkeley, USA, and co-workers.
CTL1 is also found in animal cells, Chao noted, and thus the study concluded that «characterizing CTL1 as a new regulator of protein sorting may enable researchers to understand not only ion homeostasis in plants but vesicle trafficking in general.»
The 2013 Nobel Prize in Physiology or Medicine goes to James E. Rothman, Randy W. Schekman and Thomas C. Südhof for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells
EMCCDs are the ideal detector for low light applications; single molecule detection, ion (calcium) imaging, vesicle trafficking, super-resolution and TIRF.
In fibrosarcoma and neuroblastoma cells, huntingtin shows discrete punctate, perinuclear localization overlapping largely with the trans - Golgi and cytoplasmic clathrin - coated vesicles, implicating huntingtin in vesicle trafficking.
During a brief post-doctoral fellowship with Harvey Lodish at the Massachusetts Institute of Technology Rothman learnt to work with viruses and cell - free systems — thus acquiring skills that would later prove invaluable for identifying molecules involved in vesicle trafficking.