Sentences with phrase «cell subtypes»
"Cell subtypes" refers to different types or categories of cells within a larger group or classification. It means that within a group of similar cells, there are distinct variations or variations in function, structure, or other characteristics. Full definition
In HIV infection, however, a T cell subtype called the central memory CD4 + T cell appears to enter the cell cycle and undergo apoptosis — cellular suicide — in vast numbers.
scientificamerican.com
Within the data, the team pinpointed expression signatures specific to known cell types (e.g., enterocytes, goblet cells, Paneth cells, tuft cells), specific cell subtypes or populations (e.g., enterocytes at different stages of maturation), and rare cell types (e.g., M cells).
Project: Retina Ganglion Cell Subtype Specific Cell Death in a Mouse Model of Human Primary Open - Angle Glaucoma
He conducted his postdoctoral research at Brigham and Women's Hospital / Harvard Medical School, where he researched the role of the Wnt signaling pathway in mouse models of kidney disease, and was part of a team that discovered a stem cell subtype responsible for solid organ fibrosis.
With treatment, T - cell subtypes normally associated with allergic responses diminished, while a novel T - cell population that likely would not mount an allergic response expanded.
Immunotherapy caused an increase in peanut - specific T cells, accompanied by a change in the distribution of T - cell subtypes over time.
They also applied it to human brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.
«Discovery of new T - cell subtype opens window on rheumatoid arthritis: Finding flows from researchers» use of high - tech tools to deeply and efficiently characterize patient cells.»
Although there is significant evidence implicating T - cells — particularly their interactions with B - cells, which produce antibodies — it has been unclear which T - cell subtypes help orchestrate the damaging immune responses that underlie rheumatoid arthritis.
Our results suggest that the lipid - activated transcription factor PPARγ orchestrates a transcriptional response leading to the development of a dendritic cell subtype with increased internalizing capacity, efficient lipid presentation, and augmented potential to activate iNKT cells.
The data also revealed the existence of previously unrecognized cell subtypes and provided support for reclassifying known ones.
Immune cell subtypes might shift in someone who has an infection or an allergy or an autoimmune disease, for example; or they may vary for different population groups.
The schematic diagram depicts the potential cell subtypes that make up ES cell culture.
Scientists discovered six new dendritic and four new monocyte cell subtypes in a new study.
She observed that the repertoire of immune cell subtypes differed between normal and engineered mice, and furthermore, that T cells of engineered mice fed a «western» (fatty) diet produced inordinately high levels of pro-inflammatory cytokines.
Antigens are exposed on the surface of DCs in a protein complex along with major histocompatibility complex (MHC) proteins that mediate the recognition and activation of the appropriate T cell subtype.
«Potential to predict peanut allergy immunotherapy outcomes: Successful immunotherapy induces changes in immune cell subtypes.»
The diagnostic test is a physiologic measurement probing retinal ganglion cell subtypes to assess visual functions that may be lost early in glaucoma.
«We have identified similar immune cell subtypes that are present in the human heart,» Lavine said.
Both memory T cells subtypes can be reactivated with current immunotherapy treatments, and reactivation of both requires DC1 dendritic cells.
TIGIT (T - Cell Immunoreceptor With Ig And ITIM Domains) is a co-inhibitory receptor expressed on all T - cell subtypes and NK cells.
Researchers continue to identify new T - cell subtypes — and devise ways to use them to fight cancer.
In doing so, they are reclassifying the cell subtypes that occur during spermatogenesis.
Correlating Different Mast Cell Subtypes to Equine Asthma Diseases Researchers will investigate differences in mast cell subtypes found in the airways of heathy and asthmatic horses to help identify better diagnostic and treatment strategies for equine asthma.