Sentences with word «erythroid»

The proteins in them are characteristic of fetal and embryonic cells rather than of mature erythrocytes, and the authors take care to call them «erythroid cells» rather than true erythrocytes.

The cytokine - inducible SH2 domain containing protein CIS negatively regulates signaling by promoting apoptosis in erythroid progenitor cells.

Human erythropoiesis is a complex multistep process that involves the differentiation of early erythroid progenitors to mature erythrocytes.

Sustained activation of nuclear erythroid 2 - related factor 2 / antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice.

Targeted disruption of nuclear factor erythroid - derived 2 - like 1 in osteoblasts reduces bone size and bone formation in mice.

Surprisingly, and in stark contradiction of the established dogma, we discover that the first events in myeloid and erythrocyte lineage commitment involve massive expansion of the repertoire of enhancers (approximately 6,382, 5,834 and 4,859 de novo enhancers in the myeloid, lymphoid and erythroid respectively).

High level erythroid lineage - directed gene expression using globin gene regulatory elements following lentiviral vector mediated gene transfer into primitive human and murine hematopoietic cells.

Cell culture steps were used by both groups to let cells recover after thawing and / or electroporation, and additionally to generate erythroid progenitor cells from edited CD34 + cells [1].

Therapeutic levels of fetal hemoglobin in erythroid progeny of -LCB- beta -RCB-- thalassemic CD34 + cells following lentiviral vector - mediated gene transfer.

Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.

«Long non-coding RNA mediated anti-apoptotic activity in murine erythroid terminal differentiation»

This will include both a series of public health related research presentations focusing on anemia, as well as basic biology / laboratory based presentations focusing on iron metabolism and erythroid biology as it relates to this question.

Erythroid differentiation: a matter of proteome remodeling UBE2O as a key player of proteome remodeling and RBC maturation.

Targeted deletion of the gamma - adducin gene (Add3) in mice reveals differences in alpha - adducin interactions in erythroid and nonerythroid cells.

A recent review from Juliana Xavier ‐ Ferrucio and Diane S. Krause (Yale University, New Haven, CT, USA) focuses on recent advances in the identification and characterization of bipotent megakaryocytic ‐ erythroid progenitors (MEPs).

Sulforaphane * 1, a phytochemical contained in broccoli sprouts at relatively high concentrations, has been known to exert effects of cancer prevention by activating a transcription factor, Nrf2 (nuclear factor (erythroid - derived 2)- like 2), which regulates the balance of oxidation — reduction in the cell, and by enhancing anti-oxidation ability of the body and detoxication of chemical compounds taken into the body.

Porphyrin formation entails PBG deaminase - dependent HMB synthesis; limiting (or absent) expression of downstream enzymes in the heme biosynthesis pathway (grey) leads to non-enzymatic cyclization of HMB to form uroporphyrinogen I, as in the erythroid cells of CEP patients (Discussion).

Gerald de Haan did his PHD at the University of Cologne, Germany and the University of Groningen, the Netherlands, under supervision of Prof. dr. Markus Loeffler and Dr William Nijhof, on vivo models addressing the issue of erythroid and myeloid lineage competition.

During the end of the red blood cell maturation process, one lncRNA in particular was found to be highly expressed; the group dubbed this lncRNA «long intergenic non-coding RNA - erythroid - pro-survival» or lincRNA - EPS.

When veterinary pathologists examine bone marrow samples submitted by your veterinarian, they look for abnormalities in the «founding» cells (progenitor cells, myeloid cells, stem cells) that produce the white cells and the «founding» cells that produce red cells (erythroid cells, erythroid precursor cells).