Sentences with phrase «gene in this region»

They add that other genes in the region of the genome around Gp - 9 are probably involved in regulating fire ant social organization as well.
The race was on, with the two teams probing for candidate genes in that region to determine which bore the APECED mutations.
Other genes in this region remain unchanged, indicating a clustered yet specific and patterned response.
However, the team also found virulence genes in regions of the genome that are not so variable.
The researchers concluded it is likely that ancient farmers favored the VRN - D4 variant of the vernalization gene in this region because of its high adaptive value in the local environment.
Two genes in this region changed their expression patterns when submerged, and one of these, called Sub1A - 1, could turn submergence - intolerant plants into flood survivors when artificially inserted into the genome.
The findings suggested that a mutated gene in this region was responsible for many cases of both conditions, but scientists did not pinpoint a specific gene.
But difficulties in pinning down susceptibility genes in those regions led geneticist Matthew State at Yale University Medical School to take a different approach.
Genes in these regions warrant further investigation to uncover the biological processes underlying the condition.
Of 73 genes in this region identified by genetic analysis, 49 have been located on the sequence; P - element insertions have been mapped to 43 genes.
«We find the existence of at least four disease - associated haplotypes in the two nearby chromosome 5 regions intriguing, and speculate that there may be genes in the region affecting traits for which dogs are bred in this population.»
Because methylation of CpG islands associated with the first exon is particularly predictive of gene expression (e.g., Plume et al., 2012), characterizing individual differences in methylation of inflammation - related genes in the region of the first exon may be particularly informative.
Finally, we found that genes in regions of the genome with a low recombination frequency tend to have a higher ratio of non-synonymous to synonymous substitutions, likely due to the accumulation of slightly deleterious non-synonymous substitutions.
Some of the genes in this region encode toxins.
Finally, the team identified a network of genes in these regions that exhibit changes in expression when the normal boost from serotonin is lacking, and these changes depended on how long the drug was given.
The result is that individuals with the most common form of the disease have a total of three copies of all the genes in this region.
Each gene in the region is being studied to see whether it is abnormal in breast tumours.
They first mapped it to chromosome 5, and after narrowing its location, found two genes in that region.
The researchers knew to look for their gene in the region between the shortest insert that caused infertility and the longest one that left flies fertile.
The genes in the regions of the genome that have been modified by PRC2 are switched off, or become silenced.
In the new study, the researchers focused on one of the genes in this region, called complement component 4, or C4, which is known to be involved in the immune system.
Indeed, researchers have found a gene in the region that is likely linked to vision.
There are 28 genes in this region, half of which are thought to play a role in brain development, Froguel says.
«That region — or rather, a gene in that region — is apparently extremely sensitive to [copy - number] dosage,» Daly says.
Under normal circumstances, genes in this region are inactive, or silenced, on maternal chromosome 15 but active on paternal chromosome 15.
Zoghbi's lab meticulously analyzed each gene in this region, systematically eliminating genes based on sequence differences between healthy controls and Rett syndrome patients.
The 2013 study, which was led by David Altshuler (now chief scientific officer at Vertex Pharmaceuticals), had shown that one gene in that region, SLC16A11, harbored several suspicious mutations, and more detailed genetic mapping of the region strengthened the case for focusing on it.
By definition the attributes conferred on us by genes in this region must evolve faster than other attributes,» Dr Stefansson added.
To that end, Kandel and his team gathered a sample of human brains and measured the activity of genes in that region.
For the candidate gene in the region, RSPO3, we demonstrated expression in key liver - resident effector cells, such as human and murine cholangiocytes and human hepatic stellate cells.
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