Sentences with phrase «human glioblastoma»
"Human glioblastoma" refers to a type of brain cancer that occurs in humans. It is a very aggressive and dangerous form of cancer that develops from cells in the brain called glial cells. Full definition
The investigators then confirmed that these four factors and their corresponding regulatory elements — the DNA segments to which transcription factors bind — were active in from 2 to 7 percent of human glioblastoma cells, cells that also expressed a known stem cell marker.
sciencedaily.com
He had long despaired of oncology's dirty little open secret: that when scientists transplant bits of human glioblastomas into mouse brains, the standard research approach, the result doesn't mimic what happens in people.
Son et al., SSEA - 1 is an enrichment marker for tumor - initiating cells in human glioblastoma.
An initial library of 15 biodegradable particle formulations was tested for their ability to carry siRNAs into human glioblastoma cells that were genetically engineered to make green fluorescent protein (GFP).
Figure 2: Abnormal accumulation of the FGFR - TACC fusion protein (red) in glioblastoma stem cells isolated from a primary human glioblastoma with fused FGFR - TACC genes.
Then, mice would have to be induced to grow human glioblastoma tumors for further trials.
Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature, 455 (7216), 1061 - 1068 DOI: 10.1038 / nature07385
Glauco Souza of Nano3D Biosciences in Houston, Texas, and his colleagues incubated human glioblastoma cells from brain tumours with iron oxide and bacteriophages — viruses that infect bacteria and can bind to, but not harm, mammalian cells.
The team found that exposing samples of human glioblastoma tumours grown in a dish to the Zika virus destroyed the cancer stem cells.
In a series of experiments, the researchers first identified a set of 19 transcription factors that were expressed at significantly greater levels in cultured human glioblastoma stem cells capable of tumor propagation than in differentiated tumor cells.
VIRUS VICTORY Zika virus (green) infects and kills stem cells (red) in human glioblastoma tissue, without infecting healthy brain cells.
Glioblastomas in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor stem cells, were nothing of the kind.
Dr. Iavarone's paper is titled, «Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma.»
These cancer stem cells were used to create preclinical models relevant to human glioblastoma.
Anticancer effects of niclosamide in human glioblastoma.