Sentences with phrase «in specific genes»

Researchers have discovered that mutations in a specific gene are responsible for a hereditary form of melanoma.

The reason for all the types of mutations is variations in the specific genes passed on from each parent.

The differences reveal where mutations may have occurred in specific genes.

About 5 - 10 % of all cancers are inherited, meaning that mutations in specific genes are passed from one blood relative to another.

Researchers at Lund University in Sweden have found a new type of biomarker that can predict the risk of type 2 diabetes, by detecting epigenetic changes in specific genes through a simple blood test.

In contrast to traditional genetic testing, which usually checks for variants in specific genes, high - throughput sequencing has the potential to reveal a number of secondary findings, i.e., genetic variants with medical relevance but not related to the condition that merited the test.

«Heart toxin reveals new insights into HIV - 1 integration in T cell genome: Digoxin exposes link between T cell activation and targeted HIV - 1 integration in specific genes.»

It will be important to find ways of reprogramming skin, or other cells, that do not rely on viruses, moreover, the relatively low frequencies obtained need an explanation, as do the differences between the iPS cells and ES cells and in the specific genes used in the two papers.

Early on, researchers realized they could use CRISPR - Cas9 to make single cuts in a specific gene pretty easily.

Sanger COSMIC identification numbers signify precise mutations at particular loci in specific genes enabling direct identification of specific cancer mutations.

It has been shown that the induction of an altered phenotype by a maternal protein restriction diet during pregnancy involves changes in DNA methylation and histone modifications in specific genes, including the glucocorticoid receptor (GR)(33 % lower; P < 0.001) and PPAR?

A herding dog — well, it herds and no, it does not need to be trained to have that instinct (as in a specific gene / genes).

The Guardian article of August 21, 2015 describes the changes in a specific gene sequence associated with the regulation of stress hormones.

Luxturna is the first of a crop of treatments that target diseases caused by mutations in specific genes, and thus is referred to by many as the first gene therapy in the U.S.

Individuals who had a particular variation in a specific gene (platelet derived growth factor D; PDGFD) had a markedly increased risk of adrenal suppression, both in the children with asthma and adults with COPD.

Following up on findings from a an earlier genome - wide association study (GWAS) of type 2 diabetes (T2D) in Latinos, researchers from the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) traced an association detected in that study to variants in a specific gene, SLC16A11, and uncovered two distinct mechanisms by which those variants disrupt the gene's function in liver cells, possibly contributing to the pathogenesis of T2D.

Larsson is at the forefront of merging paleontology and molecular biology in an effort to connect major evolutionary changes — the development of new species and new characteristics, new shapes and structures, new kinds of animals — to changes in specific genes and in how those genes are regulated.

Members of some families are at higher risk than others to develop tumors that originate from these cells due to mutations in specific genes.

Luxturna is the first gene therapy approved in the U.S. that targets a disease caused by mutations in a specific gene.

By also examining this genetic region in two other families with similar disorders, the researchers were able to pinpoint a mutation in a specific gene, NT5E, which is involved in breaking down calcification in the arteries.

The Yale - led study performed whole exome sequencing ¬ — a technique for sequencing all the expressed genes in a genome ¬ — on TNBC tumors to identify mutations in specific genes or pathways that may indicate response or resistance to the standard of care, which is anthracycline / taxane (ACT) chemotherapy.

The researchers first employ a process termed «mutagenesis» to create random variations in a specific gene.

«It gives us enough reason to begin to look in earnest for mutations in this specific gene,» said Cook.

Between five and 10 % of all cancers are hereditary, which means that changes (or mutations) in specific genes are passed from one blood relative to another.

Targeting Induced Local Lesions In Genomes (TILLING) is a method of inducing and identifying mutations in specific genes.

«If a patient has a mutation in a specific gene, it would be a way of giving them a normal copy to try to correct that gene.

This analysis led to the identification of recurrent mutations in a specific gene, called NFKBIE, which encodes a protein involved in the NF - kB signalling pathway.

The researchers in this study have pinpointed variations in a specific gene — MC1R — that are directly related to how old people appear to others.

Familial cancer, also known as hereditary cancer is a condition caused by mutations in specific genes that is passed from parent to child.

Mutations in specific genes are passed from one blood relative to another, creating a greater chance of developing cancer in their lifetime and at an earlier age.

Many idiopathic epileptics have inherited epilepsy: epilepsy caused by a mutation in a specific gene that they inherited from their parents.