Sentences with phrase «mode of action»

So the team began to look for alternative modes of action for the drug.

To delay the onset of resistance, it's best to use a combination of control methods with completely different modes of action.

My desire in painting is to state the existence of other realities; of other ways and modes of action in life.

In other cases, a medication with a similar mode of action can be substituted for the problematic drug.

Or they're giving him drugs that likely have no known mode of action, are unlikely to be beneficial or have never been tested on animals and are just assumed to work.

«Its unique mode of action suggests it may be a useful probe for examining energy metabolism,» she added.

This offers an organic way to protect crops through multiple modes of action on insects.

But I do not know whether it can be formulated nor whether it will require some particular mode of action.

However the identity of all of these signals, and their specific mode of action, are not known.

Most scientists assumed that this was the drug's main mode of action.

Your unique modes of action put the spotlight on political oppression both nationally and internationally.

In others washing toxic or inflammatory substances from the cat's skin surface are their primary mode of action.

A staggering 50 % of conventional medicine has no known mode of action, while another 12 % is either harmful or ineffective.

«New mode of action for HUMIRA in rheumatoid arthritis patients.»

The exact mode of action in MS is not yet known.

Its novel mode of action specifically targets and inhibits the cytokines involved in itch and inflammation with minimal activity against cytokines involved in hematopoiesis or innate immune function.

The speakers will give an overview of the empirical schema theoretic foundations, shed light on possible modes of action and evaluate the clinical evidence of schema therapy in the treatment of depression.

It has a different mode of action from other insecticides, meaning that it could also be effective against mosquitos that rest and feed outdoors, as well as mosquitoes that are resistant to the standard insecticides used on bed nets and indoor spraying.»

But for the time being, he suggests they use as many different pre - and post-emergence herbicides with as many modes of action as possible in every field in every year.

The study is «a useful contribution to the field,» and packing two modes of action into one drug has several advantages, says Christophe Biot, a malaria researcher at the Université des Sciences et Technologies in Lille, France.

Lopresti AL, Hood SD, Drummond PD (2012) Multiple antidepressant potential modes of action of curcumin: A review of its anti-inflammatory, monoaminergic, antioxidant, immune - modulating and neuroprotective effects.

For the Jaina, the task was that of real purification, requiring definite modes of action and abstinence from action.

We have already shown that serelaxin prevents the organ damage that occurs during an episode of acute heart failure3 and we will continue to investigate other modes of action.»

The researchers were surprised by the compounds» shared mode of action because unlike the small sized TDA, polyether compounds are quite large.

In the current study, pesticides with a particular mode of action also corresponded to higher colony mortality.

Given these findings, we proposed that the dominant mode of action of the ApoC - III ASO in mice is to remove the inhibitory effect of ApoC - III on the clearance of TRLs through LDLR and LRP1, which act in a redundant manner with respect to TRL clearance (17, 23).

What Christ brought to man was not a new code - book of detailed regulations, but a new orientation and attitude from which new modes of action flow.

An indigenous church, young or old, in the East or in the West, is a church which, rooted in obedience to Christ, spontaneously uses forms of thought and modes of action natural and familiar in its own environment.

«Mensacarcin's unique mode of action indicates it might represent a promising lead for the development of new anticancer drugs.»

The parent company AstraZeneca is well aware that antibody treatments or «biologicals» with their precise mode of action, are a key part of medicine's future.

More effective treatments for breast cancer may follow now that researchers have discovered a second mode of action for the anticancer drug tamoxifen.

More recently, this effort met with the possibilities offered by more recent — and maybe more immaterial and intangible media — such as Internet and social media, which will provide an alternative mode of action for the evaluation of what constitutes an efficient social movement

That two mirror molecules can have a completely different mode of action became widely known in the aftermath of the tragic effects the sedative drug Contergan had on unborn children in the early 1960s.

Professor Bruce added: «This is an important additional finding as it is an increasing concern that although herbicide resistance has been increasing steadily since the 1970s, no new herbicide mode of action has been commercialized since the 1980s.»

As the study from the National Food Institute shows that butylparaben probably has an endocrine disrupting mode of action, this new knowledge about butylparaben may have an impact on how authorities in the future choose to regulate the use of the substance in different products.

These findings demonstrate that the capacity for increasing muscle growth by manipulating TGF - ß signaling pathways is much more extensive than previously appreciated and suggest that muscle mass may be controlled at least in part by a systemic mode of action of myostatin.

Inferring genetic networks and identifying compound mode of action via expression profiling

To investigate the potential involvement of Rac in Mcf1 mode of action we micro-injected Mcf1 into Drosophila embryos expressing either dominant - negative (RacN17) or constitutively active (RacV12) versions of the small GTPase, Rac, in hemocytes.

Scientists took more than 100 years to discover that aspirin's ability to relieve aches and pains was due to its inhibition of synthesis of the hormone prostaglandin - and aspirin has not been unique in its elusive mode of action.

Bavituximab's presumed mode of action is to block immunosuppression while activating a tumor - killing T - cell immune response.

In an interdisciplinary approach, the team will first systematically identify genes that are required for this differentiation process - information which will then be used to investigate their molecular mode of action, their targets, and if and how they interact with each other.

AcCoA complex reveals an additional mode of action for the antimetabolite N - pentyl pantothenamide (N5 - Pan) is published in Biochemistry.

Finally, the scientists commented that «Antioxidant treatment consistently protects cells from the lipid peroxidation caused by fluoride exposure, suggesting that oxidative / nitrosative damage is the major mode of action of fluoride».