Sentences with phrase «number of genes»

The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

Until then, the evidence for the existence of a new biological domain had been largely based on studies of small numbers of genes.

Laws of population genetics predict that, on a purely theoretical ground, such a high number of genes should translate into an extremely elevated frequency of unaffected carriers of mutations.

Yet progress in understanding the connections between a growing number of genes and conditions such as depression, bipolar 1 disorder and schizophrenia hint at what may eventually come.

Here, an increasing number of genes begins to influence variability.

It is entirely possible to pass on a different number of genes to offspring.

The actual number of genes may be 10,000 to 11,000, some of which have counterparts in the human genome.

Large numbers of genes are found in almost every cell.

That is, we believe only a small number of the genes determine the cell types, and we favor many genes having 0 weights.

Ikaros's function is to bind DNA and regulate the activity of a large number of genes in cells.

«We didn't know before these results came out that there are a large number of genes with expression levels systematically different between mouse and human,» said Ross Hardison, Ph.D., director, Huck Institute for Comparative Genomics and Bioinformatics at Pennsylvania State University, University Park, and a co-senior author on the main Nature study and other publications.

A large number of genes involved in nervous system development and function were also deregulated.

At last year's Brainstorm Health conference in San Diego, Bergh found himself sitting at dinner with Othman Laraki, the cofounder and CEO of Color Genomics — a company that extracts the DNA from a customer's submitted saliva sample and then looks for a set number of gene mutations known to be associated with increased risk for developing certain hereditary cancers or heart conditions (depending on the test).

Fisher's exact test as implemented in R66 was run to test for enrichment or depletion of numbers of gene families for each molecular function category in the novel versus ancestral gene sets.

A dog with normal patellas whose dam had luxating patellas will likely be carrying a much higher number of the genes needed to produce luxating patellas than a dog from two normal parents.

We found that an unusually high number of genes affected by these DNA deletions / duplications are associated with the functioning of synaptic transmission between nerve cells.

A peek at tardigrades» genetic diaries may dispel a rumor about an amazing feat the tiny creatures were supposed to perform: borrowing large numbers of genes from other organisms.

The authors reported that the genome of the domesticated watermelon contained 23,440 genes, roughly the same number of genes as in humans.

But Reid cautioned that the small patient sample and the small number of genes analyzed means that the results should be considered preliminary until a larger study is done.

Strikingly, up to 30 per cent of the total number of genes in an organism may be orphans and these genes may rapidly acquire functions.

«In reality, there are a vast number of genes involved in any given disease, and several different mutations may exist in the same gene.»

Less clear is how this misfolding relates to the growing number of genes implicated in PD through analysis of human genetics.

«It might be difficult to imagine why the large number of gene variants that together give rise to traits like [autism spectrum disorder] are retained in human populations,» co-author and genetics and neuroscience professor Joel Gelernter said in a statement from Yale University.

The octopus also has an abnormal number of genes controlling neuron development and interactions between neurons — processes likely associated with learning and intelligence.

In - silico analysis can yield important insights into this aspect, facilitating comparison of two or more classes of genes comprising of a large number of genes within each group.

Rice, for example, may have up to 50,000 genes — about the same number of genes as wheat or corn — but its genome is only 1/38 the length of the wheat genome.

Polygenic traits are controlled by unknown numbers of genes.

If a puppy has luxating patellas, he or she inherited the critical number of genes from both parents that were needed to express the trait.

Depending on the type of pir, the amount can fluctuate, as can be seen by the large variance in number of genes per cluster.

Today, there are a fair number of gene - silencing drugs in late - stage development and dozens of companies working in the space — and it feels like we could be close to a tipping point.

Even with the phenotype, perhaps there is a «trade off involved» in that the same underlying genetic sub-scripts serve other purposes, or perhaps the sheer numbers of gene - hormonal permutations mean it will always manifest itself due to pure statistics.

For instance, one admits that in much of evolution (probably all above the bacteria), evolutionary changes involve enormous numbers of genes, rather than a selection of one or two particular genes (although that occurs in a few instances, possibly, for instance, in industrial melanism).

A large number of genes previously not linked to developmentally - regulated neuronal death or neurodegenerative pathologies were identified.

«There are virtually an infinite number of genes you could look at,» Moller says.

There's the challenge of CRISPR» ing an unprecedented number of genes without compromising the viability of the designer pigs and without introducing aberrant edits.

12,500 Approximate number of genes in the human genome whose function remains undetermined.

The research could be a key to understanding how the nervous systems of other animals — including humans, whose brains have billions of neurons — produce such a dazzling array of cell types from a modest number of genes.

If she finds a large number of genes governing processes that tuck away carbon dioxide, for example, the wetland likely has high carbon storage potential.

Understanding this process - which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on - helps explain how complex organisms can arise from a finite number of genes.

«The large number of genes makes it less likely that one solution to beat obesity will work for everyone and opens the door to possible ways we could use genetic clues to help defeat obesity,» she says.

She also says that other recent work confirms that it's possible to compute the impact of large numbers of genes using simple arithmetic.

They found additional changes to the small number of genes carried within the mitochondria, the cell's powerhouses.