Sentences with phrase «of osteocalcin»

Women's blood levels of osteocalcin increased during exercise, the team reported.

His team are currently exploring the possibility of osteocalcin as a treatment option for infertile men.

Although DNA can survive only up to 100,000 years and is rarely found in useful quantities in specimens even half that old, the team has found measurable amounts of osteocalcin in 120,000 - year - old bones.

Like matrix Gla protein, vitamin K is essential to increased production of osteocalcin, a protein hormone important to bone metabolism and insulin sensitivity.

The exact function of osteocalcin remains unclear.

Maternal and offspring pools of osteocalcin influence brain development and functions.

All these factors protected them from developing diabetes and obesity — just the opposite of the osteocalcin - deficient mice.

«The addition of osteocalcin as a metabolic regulator may one day lead to novel therapies, but we need to understand much better how it works and how it fits into physiology before such therapies can be attempted in humans,» says endocrinologist Mitch Lazar, director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania.

Studies have shown that, for some people, changes in blood concentrations of osteocalcin may even stave off the development of diabetes.

But the idea that bone itself can affect other tissues took root only a few years ago with the discovery of osteocalcin.

When Kandel's team silenced the gene in mice, they had memory deficits in spite of osteocalcin's presence.

Although the metabolic responses observed are consistent with the cellular consequences of osteocalcin exposure in pancreatic β - cells and myoblasts in vitro (27 — 29, 61), the metabolic effects of exercise and WBV may not be dependent on osteocalcin per se.

Although the metabolic effects of osteocalcin are still being elucidated (58, 59), several studies suggest that undercarboxylated osteocalcin regulates glycemic control and lipid metabolism in mouse models (27, 30, 60).

Direct manipulation of osteocalcin will be required to determine whether increases are required for enhanced glycemic control with exercise and WBV.

Mice that were deprived of either RbAp48 or osteocalcin exhibited poorer recall, and healthy levels of osteocalcin correlated to better memory in both young and old animals.

A deficiency in vitamin K may result in an analogue of osteocalcin that has been found in the blood of osteoporotic patients.

When the researchers mimicked the process outside of a live animal, moreover, they verified the hormonal activity of the osteocalcin that was released.

Bones One cup of boiled spinach provides over 1000 % of the RDA of vitamin K that can prevent excess activation of osteoclasts (the cells that break down bones), as well as promote the synthesis of osteocalcin, the protein that is essential for maintaining the strength and density of our bones.

She notes, however, that the researchers did detect increased levels of osteocalcin, a hormone that indicates bone formation.

A cup of most greens provides several times the minimum recommendation for vitamin K, a vitamin needed for the production of osteocalcin, a protein essential for bone health.

Additionally, it allows for the optimal form / function of osteocalcin (a «non-collagen» protein) which is incorporated in bone, during bone formation.

«One of osteocalcin's functions is to increase insulin production, which in turn reduces blood glucose levels,» Ferron explained.

This is explained by another finding from the Karsenty lab: circulating levels of osteocalcin are much higher in younger mice than in older mice.