Sentences with phrase «specific tumor»

By exploiting these differences, scientists have developed therapies that target specific tumor types, and these targeted therapies have proven useful against most breast cancers.

This breakthrough has led to a surge in research on personalized medicine, including cancer treatments that are designed to target specific tumor - causing gene mutations.

Some cancer treatments use antibodies to target and destroy specific tumor cells.

Our team designs and delivers radiation treatments optimized to each patient's specific tumor type, size, stage and location.

Rice University and MD Anderson researchers have developed a technique that uses fluorescent nanotube - based probes to locate specific tumors in the body.

Instead of targeting specific tumor antigens, this approach relies on endogenous antigens (including neoantigens) released during tumor lysis by treatments such as chemotherapy or local radiation.

Researchers at Rice University and the University of Texas MD Anderson Cancer Center have refined and, for the first time, run in vivo tests of a method that may allow nanotube - based probes to locate specific tumors in the body.

«We reasoned that this retained synthetic essential gene might be required for cancer - promoting actions when the cancers lose specific tumor suppressor genes.»

Primary treatment for specific tumor types Indications for the use of external beam radiation therapy for the primary treatment of tumors has expanded significantly with the emergence of SRS for pets.

«This study provided a conceptual framework for the discovery of «traceable» targets in cancers harboring specific tumor suppressor deficiencies.»

«We searched for genes that are occasionally deleted in some cancers but which are retained in cancers caused by specific tumor suppressing genes, such as PTEN,» said Di Zhao, Ph.D., Odyssey postdoctoral fellow in Cancer Biology and first author on the Nature paper.

«Being able to safely take tissue samples will also allow us to test for specific tumor sub-types and better decide the most appropriate treatment for each individual patient,» added Dr Booton.

If researchers can use the mice to gather information about specific tumor responses to specific drugs, then they can bank that information to be used in the general population.

One limitation of our study is the use of metastatic samples from various organ sites, potentially influencing expression via differences from the organ - specific tumor microenvironment.

The development of diagnostic and therapeutic nanodevices based on engineered recombinant proteins capable of recognizing specific tumor cell receptors is currently actively pursued.

Matsuzaki J, Gnjatic S, Mhawech - Fauceglia P, Beck A, Miller A, Tsuji T, Eppolito C, Qian F, Lele S, Shrikant P, Old LJ, Odunsi K. (2010) NY - ESO - 1 specific tumor infiltrating CD8 + T cells in human ovarian cancer: negative regulation by LAG - 3 and PD - 1.

This process is also called «passive tumor targeting» since specific tumor targeting ligands are not used.

Onsite at Norris Cotton Cancer Center located at Dartmouth - Hitchcock Medical Center in Lebanon, New Hampshire, members of Cancer Mechanisms are embedded in several disease - site specific tumor boards.

Promoter hypermethylation of tissue specific tumor supressor genes and point mutation in K - ras, c - myc proto - oncogenes in urinary (transitional cell) bladder carcinoma

These are more specific therapies such as monoclonal antibodies and cancer vaccines, which target specific tumor antigens.

Indications for radiation therapy (RT) include the primary treatment of specific tumor types, such as nasal tumors and brain tumors, adjuvant treatment of incompletely excised tumors, and palliation to improve quality of life for patients with non-resectable or advanced cancers.

These decisions are typically guided by the drugs» average historical success rate for different types of cancer, rather than any understanding of how the chemotherapy drug will interact with the genetic profile of a specific tumor.

Some cell types were not killed by treatment with PAL, suggesting it could be used as a specific tumor therapy.

However, many tumor proteins do not provoke T cells to attack, so T cells must be removed from the patient and programmed to attack a specific tumor molecule.

You could engineer that in a dish, and using the patient's own cells, you could develop a model of their specific tumor to test out drugs,» he said.

«This is what we have dreamed about: drugs that can be targeted to a patient's specific tumor, to the mechanism that caused the cancer,» says Alice Shaw, Martensen's oncologist and a chief investigator in the Xalkori clinical trial at Mass General.

That came up in an immunotherapy discussion that I had at Davos with Carl Jeun and Jose Bisalga, when you're working on immunotherapy and you have specific targeted tumors how, you know, is it still from a regulatory standpoint, is it still moral to wait and try to do other when you have a specific tumor that's specific to a particular person.

The FDA has never approved a drug that was not aimed at a specific tumor type such as breast cancer, but if a drug shows promise for a particular pathway involved in many tumor types, it could be approved for that use, he said.

The combination of immune regenerative strategies with chemotherapy, or novel therapies targeted to a specific tumor, is a more effective way to wipe out active cancer cells while also enabling the immune system to combat residual cancer cells, thereby reducing the potential risk for reemergence of the disease.

«This means that the vast majority of cancer patients who do not have actionable mutations, or have not responded to, or have relapsed after chemotherapy or targeted therapy, now have access to additional tests that can help their oncologist select the treatment best suited to their specific tumor,» says the tests» lead developer, Andrea Califano, Dr., chair of systems biology at Columbia University Vagelos College of Physicians and Surgeons.

The second test, DarwinOncoTreat, homes in on the entire complement of master regulator proteins responsible for launching and maintaining a specific tumor, to predict the drugs that, by interfering with these proteins, will most likely benefit the patient.

Every child's treatment plan is individualized, based on the patient's needs and the specific tumor, utilizing cutting - edge technology and the latest research.

Your child's treatment will be fully individualized towards his specific tumor type and personal medical characteristics.

11/19/2007 New Technology to Treat Breast Cancer Shows Promise in Early Application Physicians at the Rebecca and John Moores UCSD Cancer Center will present the initial outcomes of their use of a new device that delivers radiation therapy to a specific tumor site at the annual meeting of the Radiological Society of North America (R...

This process activates the CD8 T cell and causes it to divide, creating millions of CTLs to kill tumor cells that bear that specific tumor antigen, including neoantigens.

The notion that a drug could fight cancer without targeting a specific tumor challenged conventional thought, as did the idea that an agent could exploit the immune system without directly stimulating it.

Provenge and other therapeutic vaccines involve personalized therapy that targets the patient's specific tumor.

Your veterinarian will be able to explain how the specific tumor in your animal is likely to respond to treatment and behave in the future.

Based on the specific diagnostic information that has been obtained for your pet, your veterinarian may be able to predict how the specific tumor in your animal is likely to respond to treatment and behave in the future.

The prognosis for pets diagnosed with intestinal tumors will depend on a variety of factors, including the specific tumor type, the stage of the disease and whether the cancer has spread to other organs.

The addition of an MRI would reveal the specific tumor and the extent that the tumor extends into the surrounding muscle tissue.