Sentences with word «thiol»

At the same time it increases the content of Thiol in the skeletal muscle neutralising various nitrogen - based radicals.

CDDO - Me reacted with thiol groups as determined by detection of specific adducts by LC - MS (Tables S1 and S2 and Figure S3 in Data S2).

Dissolved hydrogen sulphide, H2S (aq), then penetrates the wood, where it is transformed into solid reduced sulphur compounds, such as thiols, R - SH (R denotes an organic part), in the lignin of the wood and to iron (II) sulphides when iron ions are available.

The researchers achieved a full assignment of all signals to specific thiol ligands by using a combination of correlated nuclear magnetic resonance (NMR) experiments, density functional theory computations and molecular dynamics simulations.

Enzymes use beneficial metals for their activity and hold those metals in place with thiol groups.

A test strip that measures thiol levels in oral fluid can assist in determining oral health.

Designing molecules that selectively target thiols produced by cancer cells that cause drug resistance is the focus of many years» work by Dimmock, Das and their collaborators.

Light converts certain beer bitter acids to the dreaded 3 - methyl -2-butene-1-thiol (MBT) compound, a close relative of the malodorous thiols produced by Mephitis mephitis, the striped skunk.

Working model for the stress - induced expression of nuclear encoded NADP - MDH: Excess electron pressure in the chloroplasts leads to ROS / RNS formation, generating nitroso - glutathione (GSNO) that readily modifies sensitive thiols such as those of GapC.

Thiol resins have a powerful attraction for mercury.

Mercury has a high affinity for many thiol enzyme bonds in your body and it causes inflammation and cell death when it binds to them.

though I'm currently in low THIOL diet that restricts chocolate!

But the shape theory doesn't explain why some nearly identically shaped molecules smell vastly different, such as ethanol, which smells like vodka, and ethane thiol (rotten eggs).

Thiols offer another approach.

The researchers modified the HA molecules by attaching adamantane and cyclodextrin groups to allow the gels to flow through catheters, and they added thiol and methacrylate groups to enable post-injection cross-linking to stiffen the hydrogel.

Skunks have two glands, on either side of the anus, that produce a mixture of sulfur - containing chemicals (methyl and butyl thiols) that has a highly offensive smell.

Taken together, these findings indicate different redox requirements for the glutathione thiol / disulfide redox couple within cytosol and mitochondria of resting cells and reveal distinct regulation of their redox poise in response to inhibition of glutathione biosynthesis.

To assess thiol reactivity in cells, the ability of NAC to block HMOX1 induction was determined.

HPP - 4382 does not have electrophilic properties, as determined by its structure and lack of chemical reactivity with common thiol - containing compounds such as N - acetylcysteine.

The chemical reactivity of these groups leads to alkylation of reactive thiols and generation of ROS.

Cutting Edge: Induction of the Antigen - Processing Enzyme IFN --LCB- gamma -RCB-- Inducible Lysosomal Thiol Reductase in Melanoma Cells Is STAT1 - Dependent but CIITA - Independent

A Proprietary Blend of: Activated Charcoal, USP Sodium Bentonite Clay, Chitosan, BiAloe ® Aloe Vera, and IMD Proprietary Thiol - functionalized Silica

The di thiol chelating agent used orally 20 % gets into bloodstream, but the amount that goes through the GI helps to chelate the GI tract which can harbor toxic metals.

Water hydrolysis converts them to the more potent thiols.

The researchers studied a previously identified molecularly precise nanocluster that has 102 gold atoms and 44 thiol ligands (Figure 1, right).

To address this, the team developed a two - stage attack, first knocking down thiol levels to make the cancer cells vulnerable, then hitting them again.

Dr. Shade's favorite binder is thiol resin, because it's the most specific to heavy metals (mercury, lead and arsenic) and produces high rates of excretion.

Umashankar Das, a research scientist in the Department of Chemical and Biological Engineering and long - time collaborator of Dimmock, explained that cancer cells produce an excess of thiols, such as one called glutathione.

We should rigorously study the treatment of FMS patients with agents such as thiol and selenium to learn whether some of them benefit more from these than from the use of T3.

They talk about the most important mechanism by which Mercury causes toxicity appears to be Mitochondrial damage via the depletion of Glutathione, coupled with binding to thiol groups, which generate free radicals.

Team leader Jonathan Dimmock, a medicinal chemistry researcher in the U of S College of Pharmacy and Nutrition, explained their compounds work by interacting with thiols, naturally occurring chemicals that perform several roles in cells.

Knocking down levels of these thiols reduces cancer cells» ability to resist drugs.

First, they plan to try compounds which seek out positive charge, or are «nucleophilic», such as ammonia, hydroxyamines and thiols.

The technique relies on incorporation of the heavy isotope into a thiol from a convenient heavy water source through acid - base chemistry.

Next, a photoredox catalyst strips a hydrogen atom equivalent from the carbon, and the thiol engages in radical chemistry to transfer the deuterium or tritium in its place.

To see how a size disparity would affect the crystalline order and the system's physical properties, Olvera de la Cruz and postdoctoral fellow Zhenwei Yao devised a model system of soft particles, such as functionalized nanoparticles with grafted chains including nucleic acids or thiols.

In the butterflies, they found a plant cyanogen whose nitrile (CN --RRB- group had been replaced with a thiol (SH --RRB- group — a preemptive strike that prevents the release of cyanide.

The researchers studied a previously identified molecularly precise nanocluster that has 102 gold atoms and 44 thiol ligands (see image, right).