Sentences with phrase «to kill tumor cells»

Similarly, it may be possible to identify and validate new targets for drugs that would selectively kill tumor cells with a particular molecular context.

Natural killer cells are an important part of our body's immune response, capable of killing tumor cells and viruses, for example.

The team believes the method could be ideal for various uses including repairing tissue after a heart attack and delivering cancer drugs to kill tumor cells left behind after surgery.

Thyroid supplements do not cure the disease or kill the tumor cells causing the problem.

In a four - year study conducted on the mouse model in advanced breast cancer metastasis in the eye's anterior chamber, Petty and colleagues found that the new nanoparticle not only killed tumor cells in the eye, but also extended the survival of experimental mice bearing 4T1 tumors, a cell line that is extremely difficult to kill.

The researchers found that by killing some tumor cells directly, the viral infection exposed tumor proteins that could be detected by the immune system, triggering an immune attack on the rest of the tumor.

Palladia works in two ways: by killing tumor cells and by cutting off the blood supply to the tumor.

The results confirmed that cabazitaxel was more effective at killing tumor cells than docetaxel.

«However, we found that the drug does not kill tumor cells directly.

Scientists studying cancer have long grappled with how to make these T cells kill tumor cells.

Atif, Stein, and colleague Seema Yousuf found that low, physiological doses of progesterone stimulate the growth of glioblastoma tumor cells, but higher doses kill the tumor cells while remaining nontoxic for healthy cells.

An ideal chemotherapeutic agent is expected to specifically kill tumor cells, cause the least amount of undesirable side effect, and leave normal cells unharmed.

Researchers are experimenting with two ways to use gold nanoparticles — in one case, to reduce the collateral damage caused during radiation therapy while increasing effectiveness, and in another, as the targets of laser beams to help kill tumor cells.

These so - called «living drugs» — injected T cells genetically modified to better recognize and kill tumor cells through a perpetual process of cell renewal and expansion — are revolutionizing cancer treatment, with the first two FDA approvals of such gene - altering therapies occurring in just the last two months.

They discovered that the chemicals and radiation used to kill tumor cells damage the stem cell reservoir in the hippocampus and nearly halt the formation of new neurons in both children and adults.

Harvard Stem Cell Institute (HSCI) scientists at Massachusetts General Hospital have a potential solution for how to more effectively kill tumor cells using cancer - killing viruses.

Giving the mice antibiotics helped gemcitabine kill tumor cells, increasing the number of tumor cells going through a type of cell death called apoptosis from about 15 percent to 60 percent or more.

With standard treatments of surgery, chemotherapy and radiation, the median survival time is only 14.6 months, and improvement will only come with the ability to kill tumor cells resistant to standard treatments, according to Alfredo Quiñones - Hinojosa, M.D., a professor of neurosurgery at the Johns Hopkins University School of Medicine and a member of the research team.

We want to kill these cells that are feeding the tumor rather than just killing the tumor cells, which is less effective.»

Chemotherapies are potent toxins delivered into the bloodstream to kill tumor cells throughout the body by damaging DNA in rapidly dividing cells.

«New nanoparticle with potential to treat ocular cancer developed: Using nanoparticles to kill tumor cells inside the eye.»

Researchers now think that irradiation sometimes kills tumor cells in a manner that exposes new antigens to T cells, priming them to target other tumor cells that carry them as well, says Wenbin Lin, a chemist at the University of Chicago in Illinois, and one of the authors of the current study.

Dr. Allison: The way the field of immunotherapy is going now is toward combinatorial therapies, where we combine these different immune checkpoints blockers, and also combine these with drugs that actually kill tumor cells.

The DNRII expressed by the T cells allowed the cells to resist the hostile tumor environment and kill the tumor cells without lymphodepleting chemotherapy before infusion.

The specific antigen approach uses selected antigens that are also present in the patient's tumor so that the immune system will be educated to recognize the tumor antigen and kill tumor cells expressing the antigen.

Drug from Mediterranean Weed Kills Tumor Cells Scientists at the Johns Hopkins Kimmel Cancer Center, working with Danish researchers, have developed a novel anticancer drug designed to travel — undetected by normal cells — through the bloodstream until activated by specific cancer proteins.

M032 kills tumor cells directly through oncolytic replication and then proceeds to infect tumor cells in proximity, continuing the process of tumor destruction.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

Scientists who are in the process of developing prototypes for potential new anticancer agents that selectively kill tumor cells by interfering with the regulation of intracellular pH, have found that alkaline treatments do NOT have the desired effect - but strongly acidic treatments do.13

The macrophages are capable of killing tumor cells or sending out an alarm to T cells of the adaptive immune system that something is amiss.

When the T cells kill the tumor cells, they trigger inflammation, and that causes the fever.

Blocking the enzyme causes the cancerous cells to die, so the company is working with a telomerase inhibitor, imetelstat, that it hopes will kill tumor cells while leaving healthy ones unharmed.

Although doxorubicin can be effective at killing tumor cells, its noxious impact can hurt healthy tissues as well.

The new findings, published online in the journal Molecular Cancer Therapeutics, show that combining rapamycin with a gene therapy approach enhanced the animals» ability to summon immune cells called CD8 + T cells to kill tumor cells directly.

«I tell people, «This is not a cancer drug; it doesn't kill tumor cells.

To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years.

Rubinstein said checkpoint therapies work by cutting the brake cables on the white bloods cells that are inherently able to kill tumor cells.

An experimental drug in early development for aggressive brain tumors can cross the blood - brain tumor barrier, kill tumor cells and block the growth of tumor blood vessels, according to a study led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James).

Patients received a tandem of lenalidomide, a drug that kills tumor cells, blocks blood vessel growth, and acts on the immune system, and dexamethasone, an anti-inflammatory agent, plus one of three new agents:

Hence, a major goal of cancer scientists has been to develop drugs that prevent Mdm2 from binding to p53, and to thereby activate p53 to kill the tumor cell.

«If the only effect of the virus is to infect and kill the tumor cells, that should be fine.

The researchers found that higher levels of fibronectin allow melanoma cells to form their own protective environment that reduces the ability of BRAF inhibitors to kill tumor cells.

The researchers tested extracts from leaves for the ability to kill tumor cells and parasites and identified the active ingredient for 15 plant species.

CTL119 manufacturing begins with a patient's own T cells, some of which are removed and then reprogrammed in Penn's Clinical Cell and Vaccine Production Facility with a gene transfer technique designed to teach the T cells to target and kill tumor cells.

NK cells find and destroy virally infected cells and also play an important role in detecting and killing tumor cells.

Subsequent surgery on vaccinated patients has shown that the T cells are finding and killing tumor cells in the brain, but not enough of them.

The central idea is to encode an antigen as RNA and inject that into the skin of the patient, whose own cells then produce the protein that triggers an immune response, either to kill tumor cells or to prevent an infection.

Now, a study published online today in Science reports that vitamin C can kill tumor cells that carry a common cancer - causing mutation and — in mice — can curb the growth of tumors with the mutation.

«We were able to show that it kills tumor cells in culture and shrinks the tumor in a mouse model of DIPG.