Sentences with phrase «vaccine studies»

2015 — Began a new Ebola vaccine study in Abuja, Nigeria, using a monovalent chimpanzee adenovirus Type 3 (ChAd3) candidate developed at the NIAID and being developed by GlaxoSmithKline (GSK), the study sponsor.

«It's not just the indirect effect of protecting the mom, so it's therefore protecting the baby,» says Klein, of the Kaiser Permanente Vaccine Study Center in Oakland, Calif. «This is actually directly giving an immune response to the baby when you vaccinate during pregnancy.»

The new formula's reduced effectiveness is most likely driving the recent epidemics of pertussis, says the study's lead author, Nicola Klein, co-director of Kaiser Permanente Vaccine Study Center in Oakland, Calif..

2017 — Began a new multi-site Phase 2 Ebola vaccine study at MHRP sites in Africa evaluating a prime - boost regimen in both healthy and HIV - infected volunteers (Ad26.ZEBOV from J&J; MVA - BN - Filo from Bavarian Nordic)

Dr. Michael guided MHRP through the completion of the RV144 HIV vaccine study in Thailand, which provided the first demonstration that a preventive HIV vaccine was possible.

Researchers in the beleaguered HIV - prevention field often see glimmers of hope even in dispiriting results from clinical trials — witness the recently completed AIDS vaccine study in Thailand.

Important reports from the Weiner lab include the first DNA vaccine studied for HIV as well as for cancer immune therapy of cutaneous T cell lymphoma, the early development of DNA encoded genetic adjuvants, including IL - 12, advances in gene optimization, and advances in electroporation technologies resulting in improved gene delivery.

He will be principal investigator on a first - in - human MERS - CoV vaccine study at WRAIR, which will begin in January 2016.

Thus, this study has implications for analysis of human vaccine studies, as in addition to searching for defined lineages it is worthwhile to perform functional analysis of monoclonal antibodies that may have found new structural solutions to high affinity binding which can not be discerned from DNA sequence alone.

These studies are informing ongoing vaccine research and are helping lay the groundwork for future vaccine studies in Thailand.

1997 — Led the development of HIV vaccines for global deployment — In 1997, MHRP launched the first non-subtype B vaccine study in Thailand.

Singer refused to support a plan that would broadly sanction vaccine studies.

«Cholera vaccine study in Haiti suggests problems with current booster regimen.»

If this were the only vaccine study that had ever been done, you would interpret it differently than if there'd been a number of studies, including studies with the same two components, that were negative.

The fog around the largest AIDS vaccine study ever conducted began to lift today, as Thai and U.S. researchers for the first time publicly presented a detailed analysis of their data to over 1000 scientists gathered here at an annual meeting.

The immunological benefits from the wild mice's gut bacteria may, in part, explain a persistent problem in disease research: Why disease experiments in lab mice, such as vaccine studies, turn out very differently in humans or other animals.

Dr. Polonis has coordinated regional labs in Thailand and East Africa for the Duke University Comprehensive Antibody Vaccine Immune Monitoring Consortium (CA - VIMC) funded by the Bill and Melinda Gates Foundation, and is a standing member of the HIV Vaccines Study Section for the Center for Scientific Review at the NIH.

The findings have led to the first primary vaccine study that we are conducting as a multi-center international trial.

I joined its Community Advisory Board and enrolled in a number of VRC vaccine studies.

G.K.S. is on a Data and Safety Monitoring Board for a GlaxoSmithKline - funded RSV vaccine study in pregnant women.

• RV217 (ECHO): HIV - 1 Prevalence, Incidence, Cohort Retention, and Host Genetics and Viral Diversity in High Risk Cohorts in East Africa • Infectious Disease Surveillance (HIV, TB and Malaria) and Cohort Development Among Urban and Rural Communities • Karolinska Institute vaccine study in Tanzania testing a prime - boost HIV vaccine regimen using unadjuvanted DNA vaccines followed by a Modified Vaccinia Ankara (MVA), which was developed by MHRP and NIAID.

Therefore the group: i) characterizes the specificity of these antibody responses to identify relevant targets for a vaccine; ii) developes new approaches to test antibody responses; and iii) adoptes the immunological analysis in preclinical (in rabbits and macaques) and clinical vaccines studies to identify predictive signatures for the development and prioritization of new HIV - 1 vaccine candidates.

Vaccine studies continue today in Thailand and East Africa.

For instance, in the Salk polio vaccine studies of the 1950s, randomized trials that were mounted in some states produced estimates of the vaccine's effect on polio that were appreciably greater than estimates from a parallel series of nonrandomized trials.

VaxGen Congratulates HIV Prime - Boost Vaccine Study Collaborators and Clarifies Commercial Rights

Bea's email to Professor Michael Day, Chairperson of the WSAVA Vaccination Guidelines Group, and Sarah Mitchell of Pfizer Animal Health, provides critical analysis of their Canvac vaccine study paper, published in the December 2012 edition of the Australian Veterinary Journal [4].

RNA - transfected CD40 - B Cell Vaccines Study: Clinical Advancement of RNA - transfected CD40 - B Cell Vaccine Technology for Cancer Therapy Study Purpose: The purpose of this study is to determine whether repeat vaccinations with a cancer vaccine, made from your dog's own immune cells (B cells), can prevent relapse of lymphoma when given following a standard 19 - week course of -LSB-...]

In another Foundation - funded project, the team is using samples from the field vaccine study to help understand plague ecology and overlap among rodent communities and prairie dogs in grassland ecosystems.

Statement from Planned Parenthood Federation of America Senior Director of Medical Services Dr. Deborah Nucatola on New HPV Vaccine Study in the Journal Pediatrics

Researchers at the Kaiser Permanente Vaccine Study Center in Oakland, Calif., studied the medical records of mothers who gave birth to babies between 2010 and 2015.

Changes in Bordetella are one likely factor in pertussis's rebound, agrees Henry Shinefield, co-director of the Kaiser Permanente Vaccine Study Center in Oakland, California.

MHRP, centered at the Walter Reed Army Institute of Research, has other sites in Africa that have also expressed interest in participating in future Ebola vaccine studies.

«Results from a former AIDS vaccine study have shown that in a worst case scenario, immunization against HIV could enhance infection,» says Christiane Stahl - Hennig, who designed the project in cooperation with the former DPZ employee Sieghart Sopper.

2016 — Began first - in - human Middle East Respiratory Syndrome (MERS) vaccine study at WRAIR using GLS - 5300 vaccine, co-developed by Inovio Pharmaceuticals and GeneOne Life Science Inc..

2015 — Began a new HIV vaccine study (A004) in Uganda and Thailand.

CRI wants to see its scientists who have been involved in vaccine studies for many years actually have some say in how these company drugs are combined and how the trial is conducted — even perhaps suggesting a study that the company might not have thought of.

Vaccine studies in infants < 6 mo with novel vaccine candidates have generally demonstrated poor immunogenicity (90).

A new study from Kaiser Permanente's Vaccine Study Center found that the Tdap booster vaccine provides moderate protection against whooping cough during the first year after vaccination, but its effectiveness wanes to less than 9 percent after four years among teenagers who have received only a newer form of the whooping cough vaccine (acellular pertussis vaccine) as infants and children.

Other authors of the study include Joan Bartlett, MPH, MPP, Bruce Fireman, MA, Roger Baxter, MD, Northern California Kaiser Permanente Vaccine Study Center.

«This study demonstrates that despite high rates of Tdap vaccination, the growing number of adolescents who have received only the newer acellular pertussis vaccines continue to be at higher risk of contracting whooping cough and sustaining epidemics,» said lead author Nicola Klein, MD, PhD, co-director of the Kaiser Permanente Vaccine Study Center.

An exception to this trend is Dong Pyou Han, a former Iowa State University (ISU) biomedical researcher who last week was sentenced to prison for 57 months — almost 5 years — for falsifying results in HIV vaccine studies he participated in while working under lab head Michael Cho, The Guardian reports.

Since the outbreak exploded in August, researchers have vigorously debated how to set up Ebola drug and vaccine studies, with some advocating randomized controlled studies, in which one group of patients doesn't receive the drug, as the quickest way to get results.

The media's varied interpretations of the Thai AIDS vaccine study's results reflect the widespread confusion over the meaning of statistical significance.

WHO today issued a «donor alert,» urgently requesting a 6 - month budget of $ 10.5 million to support the vaccine study (which may require 5000 doses), as well as surveillance, treatment, and conventional prevention and control efforts.

Higgs is a co-author of the vaccine study, «Rapid development of a DNA vaccine for Zika virus,» that appears in the journal Science.

Dr. Polonis» lab has focused for many years on functional antibodies elicited by natural infection and by vaccination, utilizing samples from multiple natural history cohorts and vaccine studies; her lab is currently performing an extensive analysis of pseudovirus neutralizing antibodies in the large RV144 follow - on trial, RV306.