Lysosomes are responsible for the turnover and clearance from cells of damaged organelles and protein aggregates. (ellisonfoundation.org)
They found that the cell recycling machinery is regulated by a protein called WHAMM, and that interfering with this protein or actin polymerization itself severely inhibits the cell's ability to recycle misfolded proteins and damaged organelles via autophagy. (sciencedaily.com)
The process of autophagy degrades damaged organelles, cell membranes and proteins, and protects against the aging process (stemcellsportal.com)