Sentences with phrase «cell subpopulations»
The phrase "cell subpopulations" refers to different groups or types of cells within a larger population of cells. It means that within a group of cells, there are smaller groups that have distinct characteristics or functions. Full definition
Sphere - forming cell subpopulations with cancer stem cell properties in human hepatoma cell lines.
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Strikingly, this cancer cell subpopulation displayed enhanced expression of Bcl - xL, strongly suggesting that the upregulation of this antiapoptotic protein also supports the survival of invasive cancer cells within patients.
«We were able to boost fluorescence accumulation in the highly tumorigenic low - fluorescence glioma stem cell subpopulation using a clinically approved iron chelator,» co-corresponding author Kouichi Tabu says.
Together, these results suggested that EMT contributes to the establishment of a small cell subpopulation in malignant tumors; this population is then capable of driving the regeneration of the tumor, even when the bulk tumor cell mass is destroyed by therapeutic regimens.
Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment.
Thus, many tumors (especially solid tumors) are not a uniform mass of identical cells, but a heterogeneous mixture of different cell subpopulations.
Over the recent years, immense progress has been made in defining individual CD4 T cell subpopulations with distinct functional and developmental properties.
Conventional flow cytometry is a powerful technique for measuring cell phenotype and function, but it relies on fluorescent stains, or labels, to identify particular cell subpopulations.
HV cells cultured under self - renewing conditions were subjected to flow cytometry to separate Venus positive and negative ES cell subpopulations and injected into Rosa26 LacZ expressing blastocysts within 1 h of purification.
Using an optimized hypoxia and reoxygenation regimen, we identified a novel cycling hypoxia - selected subpopulation from human breast cancer cell lines and demonstrated that a stem - like breast cancer cell subpopulation could be expanded through repetitive hypoxia / reoxygenation cycles without genetic manipulation.
Moreover, these studies did not reveal anything about the developmental potential of the cell subpopulations.