Sentences with phrase «cellular behavior»

The living organism is often too complex to identify the specific causes of a particular cellular behavior.

Importantly, Zika virus also follows the same pattern of cellular behavior of repressing the cell's translation and stress response while promoting its own protein translation.

UB researchers have pinpointed important changes in cellular behavior that occur in Pemphigus Vulgaris, the rare, blistering skin disease shown in this microscopic image.

«Our findings fit with the growing appreciation of the importance of a cell's structural and biochemical surroundings in influencing cellular behavior.

Neglecting to trim away introns is sometimes associated with abnormal cellular behavior and disease.

They can also spur chronic inflammation and other bad cellular behavior by interacting with the receptor for AGEs, RAGE.

The virtual parts of these circuits can be arbitrarily modified to quickly create and explore cellular behaviors, even beyond what is biologically possible» explains Jakob Ruess, co-first author of the first article.

«The finding that metastases are frequently polyclonal and that subsequent cellular behavior is site - dependent also gives us insight into the origins and evolution of clonal diversity in metastatic disease.»

As a result, scaffold proteins have been exploited by evolution, pathogens, and cellular engineers to reshape cellular behavior.

Their observation provides a better understanding of cytoskeletal self - organization in general, which may in turn lead to better drug design and new materials that can mimic cellular behaviors.

Due to these crucial roles in regulating normal cellular behavior, redox status has been recognized as a key area of biological research in various diseases, including cancer.

Proteins perform virtually every task within cells, and accordingly the composition of the ensemble of proteins present at a given time generally determines cellular behavior.

Previous work by Fredberg and colleagues had documented the importance of collective cellular behavior in asthma, showing that cells comprising epithelial tissues — which line the surfaces of all organs throughout the body — can unjam and flow like a fluid, or jam and freeze like a solid.

The goal is to not only provide broadly applicable experimental tools but also help transform the way in which we think about single cells, cell - cell interactions, diseased cellular states and therapeutics so as to create a new paradigm for understanding and designing systems - level cellular behaviors in multicellular organisms.

The question of how cellular behavior is controlled is at the center of stem cell biology, and understanding the mechanisms of cell fate regulation is key for treating diseases that occur upon dysregulation, such as cancer or diabetes.

«Noise can be both an obstacle for some types of cellular behaviors as well as a useful feature for others,» Elowitz said.

ATF2 is a protein that can regulate a vast array of gene expression and therefore can contribute to many cellular behaviors and processes.

By comparing the regulatory networks of pathologic conditions, I expect to gain new insights into the central question: how do regulatory networks instruct cellular behavior under diseased condition and can we discover drugs that can alter these regulatory networks.

The concentrated antioxidants found in this amazing red fruit can actually promote and support proper cellular behavior when abnormal cells begin to wreak havoc in the body, especially for men.

The cell influences its microenvironment and, at the same time, the microenvironment influences cellular behavior — I am exploring this interrelationship.

A cell's microenvironment, the network of proteins and polymers that surrounds and connects cells within tissues, impacts a range of cellular behaviors, including stem cell differentiation.

However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.

Marie is using her passion for animal welfare and interest in medical science to explore and promote the cellular behavior needed for large - scale muscle cell production in bioreactors using serum - free media.

«Despite their importance, cellular behaviors that are largely responsible for cancer mortality are poorly understood,» Dr. Terada said.

Results from a recent set of tests on the station, called Micro-6, encouraged further study into the impact of spaceflight on the cellular behavior of these microbes.

Systems biology provides better methods of drug discovery: research teams can measure changes in genetic activity, protein levels and cellular behavior of the immune system in response to a potential vaccine.

He also envisions that this kind of nanomechanical phenotyping should allow for the development of predictive models for cellular behavior for any kind of cell.

Beyond this, there is some debate over whether or not nuclear DNA damage produces a significant contribution to aging by dysregulation of cellular behavior, though the mainstream consensus at this point - in advance of any definite study proving the point - is that it probably does.

«Now I see noise as a lens through which to look at all kinds of cellular behaviors.»

The research can be applied to pinpointing changes in cellular behavior, such as the differentiation of stem cells, metastases in cancer «or as we are studying it, the point at which a cell is going to implode because it's under autoimmune attack.»

These attachments are what turn hormones into specialized molecules, allowing them to plug into receptor molecules throughout the body, turning on and off much of the cellular behavior that makes us tick.