"Circuit function" refers to the specific purpose or task that a circuit is designed to perform. It is the intended role or job that a particular circuit fulfills within an electronic device or system.
Full definition
«Estrogen alters memory
circuit function in women with gene variant: Hormone - gene interaction may underlie sex / individual differences in mental disorders.»
«The goal of this fundamental research was to identify more of these special proteins, laying the foundation so that, in the future, scientists have a better understanding of how
neuronal circuits function.»
Researchers can potentially exploit this knowledge to not only develop more stable and precise decoding techniques, but also gain a better understanding of most basic
neural circuit functions.
The gene - by - hormone interaction's effect
on circuit function was found only with one of two versions of the gene that codes for BDNF (brain - derived neurotrophic factor), a chemical messenger operating in the circuit.
The CCP is engaged in numerous multidisciplinary projects in other model systems (e.g. fly, zebrafish, yeast) that aim to determine how complex
molecular circuits function and evolve in response to genetic and environmental changes, cellular differentiation, evolution and disease.
By combining cell physiology with pharmacology, behavioral analysis, and computer modeling, he has deciphered the existence of a central pattern generator for locomotion in the spinal cord, thereby
linking circuit function to behavior.
[55] More recent work showed, that DBS upregulates genes involved in synaptic function, cell survival, and neurogenesis [56], making some first steps at explaining the restoration of
hippocampal circuit function.
Moreover, because trans - Tango works by instigating the expression of genes in connected pairs of neurons, it also has the potential to enable scientists to
control circuit functions, says senior and corresponding author Gilad Barnea, PhD, an associate professor of neuroscience who began looking for a precise, reliable, and general way to visualize neural connections two decades ago.
Further still, working with co-author Julie Kauer, professor of medical science in the Department of Molecular Pharmacology, Physiology, and Biotechnology, they looked at synaptic and
circuit function in the mice, and they found deficits corresponding to those anatomical findings.
«Gr28bD could become a powerful tool in controlling neuronal activity and studying how
neuronal circuits function,» said Benton Berigan, a graduate student in Lorin Milescu's lab.
Thus, this study found that women who have recovered from anorexia nervosa show two related patterns of changes in
brain circuit function that may contribute to their capacity to sustain their avoidance of food.
We know that a number of structural changes also occur during this developmental period, and we now can attempt to link those changes to the changes in
circuit function.
Any genetic mutation short -
circuiting their function can have a devastating, and often lethal, health impact.
When a new granule cell neuron is made in the dentate gyrus, it needs to get «wired in,» by forming synapses, or connections, in order to contribute to
circuit function.
He joined the Polleux lab in 2017 where he studies how the endoplasmic reticulum (ER) and mitochondria networks regulate spatiotemporal dynamics of dendritic calcium in the context of synaptic integration, plasticity,
circuit function and behavior.