Even when these cells were deprived of oxygen and sugar, or exposed to chemicals that release neurotoxins such as nitric oxide, they were not damaged — although up to 65 % of
cells from normal mice died when subjected to similar treatment.
To see whether it was a true functional organ, his team transplanted the small thymus
from normal mice into mutant, thymus - free animals.
But when they were given a microRNA
transplant from normal mice through a direct tube into the gut the rodent patients went on to develop a more normal gut composition.
With no natural gut bacteria of their own, the mice offered a unique chance to see the effects of transplanted microbes
from normal mice of different ages, and to test vulnerability to infection.
They destroyed the T cells in 12 mice, five of which received marrow cells
from normal mice while seven received marrow from mice with a defective Fas - ligand gene.
Chen observed no such growth, however, when she treated retinal
explants from normal mice with a compound that blocks apoptosis.
In the latest study, the researchers injected the nine miRNAs into
zygotes from normal mice, implanted the zygotes in females, and allowed them to mature.
Untreated 3xTg mice displayed impaired learning and memory as expected, but 3xTg mice that were administered PD146176 for 3 months were
indistinguishable from normal mice in a memory test.
This shows
skulls from normal mice and from mice with a Cdh1 deficiency, whose cranial capacity has increased due to hydrocephalus.
It is hard to distinguish the ASD - model
mice from normal mice at a glance, though the model mice look more anxious, said Takumi.
After 8 weeks,
muscle from the normal mice contained nearly 50 times as much of the omega - 6 fats as omega - 3 fats, but the engineered animals
Mice that lacked gut bacteria exhibited neurochemical changes in their brains, and subsequently behaved
differently from normal mice, engaging in what would be referred to as «high - risk behavior.»
Red quadriceps (mainly type 1 fibres), diaphragm (similar proportions of type 1 and 2 fibres) and abdominal muscle (mainly type 2 fibres)
from normal mice incubated with 10 -LRB--3) m alpha - lipoic acid showed increased glucose uptake to a similar extent as 10 -LRB--6) m insulin in each of the three muscles.
However, when the intestines of these same mice were colonized by gut
bacteria from normal mice, they started to gain fat and develop insulin resistance (2, 3).
When she compared the «healer» cells from the lupus mice with «nonhealer»
cells from normal mice, she noticed several differences.
Faustman got her idea by chance while transplanting islets, the pancreatic bodies that contain beta cells,
from normal mice into others that had lost theirs to type 1, or juvenile, diabetes.
In another experiment, the research team transferred infection - combatting white blood cells — called neutrophils —
from normal mice to genetically mutated mice.
The one on top is
from a normal mouse.