Sentences with phrase «good animal model»

These tools have made it possible to make better animal models of disease and more easily study the role of individual genes.
Scientists believe having the hybrid embryos help them to create better animal models.
There is an urgent need for better animal models for laboratory research to study the Zika virus and potential treatments.
There's more to these findings than just lofty philosophical quandaries, though: If ravens really do possess a level of social cognition comparable to humans and other large primates, the birds might serve as better animal models to study this kind of behavior in the lab — which could help scientists understand why some humans are better at this kind of inference than others, and why some individuals can't manage it at all.
Understanding of the development of DPN is mostly obscure, partly due to the lack of good animal models available.
Critics charge that rabbits are not good animal models for human brain diseases and note that the dialysis patients suffered from dialysis encephalopathy, or «dialysis dementia,» not Alzheimer's disease.
The UCSF TCORS also has two developmental projects — one on risk perceptions of smoking by older Americans, and another to develop better animal models of the cardiovascular effects of secondhand smoke and exposure to other tobacco products, said Glantz.
«We have lots of good animal models in the laboratory that we can study.
From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.
The key problem for research on smallpox is that there is no good animal model for the disease.
What makes a good animal model?
What is needed for a good animal model, and how are gene - snipping tools changing the game?
Alzheimer's plagues primarily the elderly, but scientists haven't been able to figure out why because they lacked a good animal model of the disease; in earlier mouse models, amyloid plaques formed but the brain cells survived.
Herzberg said his stories dealt «with obviousness that is not obvious... the stethoscope as the eternal symbol of doctors, mice as our best animal model, eels as simple, almost boring, river fishes.
This anxious behavior mirrored that of CdLS patients, while autopsied brain tissue from individuals with CdLS showed symptoms of disease that matched those of the experimental mice suggesting that they were a good animal model.
«There hasn't been a good animal model for any kind of speech disorder,» says study author Wan - chun Liu, a senior research associate in Fernando Nottebohn's Laboratory of Animal Behavior.
Cultural stigma against diseases that some falsely believe to be weaknesses of character prevent people from coming forward for trials — a problem when there are no good animal models for diseases like depression and schizophrenia.
However these studies have been delayed because no good animal model for MERS has been developed, added Marasco.
Wild H5N1 viruses can not latch on tothe cells in a person's nose and throat, but the mutant strains created by Fouchier and Kawaoka can spread between ferrets, which are viewed as a good animal model of flu transmission between humans.
«Now that we know more about why it's occurring, it might make it a better animal model
Here, we used Splenda as a means to test the combined effect of the commercial ingredients and used one of the best animal models of ileal Crohn's disease.»
In the end, three companies formed to try to exploit CRISPR to create novel medicines, while Broad and two other companies licensed the technology to partners that hoped to engineer everything from improved crops and livestock to better animal models and industrial chemicals.
The loss was bad for the vaccine: In a series of experiments Hensley and his colleagues showed antibodies from humans and ferrets (a good animal model for influenza A studies) that had been exposed to the egg - grown vaccine did not effectively kill the circulating sugar - adorned viruses.
The condition is considered a good animal model for OCD, and it's similar to the human disorder trichotillomania, where people pull out their own hair.
The finding, by researchers at the University of Illinois at Chicago College of Medicine, was reported July 16 at the Alzheimer's Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the human disease.
The project began in 2009 when Krasnow, frustrated by the lack of a good animal model for lung disease — his area of expertise — commissioned three high school interns to search the animal world for something better.
«We need to have good animal models of these long - term cognitive problems following chemotherapy to understand what is going on and how to treat it,» Rendeiro said.
«The Medaka experiment finding of new genes affected by microgravity provides a good animal model to clarify this mechanism.»
These findings indicate that αCaMKII mutant mice should serve as a good animal model of bipolar disorder, to elucidate the pathogenesis and pathophysiology of the disorder.
Nor are there any good animal models.
Morton and her team say sheep are a good animal model for studying neurodegenerative diseases because of the relatively large size of their brains and their longevity.
Choosing the best animal model for every experiment is a cornerstone of the research approach taken by Davis Center scientists.
Furthermore, the heterozygous knock in mouse serves as a better animal model of the human disorder, as compared to the homozygous mouse, given that Huntington disease homozygosity is very rare in humans.
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