Sentences with phrase «host genes»

A number of studies have suggested that specific infections can be identified by the pattern of host genes activated during the inflammatory response.

They also look on viruses as coming from host genes that somehow escaped the host and acquired a protein coat.

As both bacterial and viral genomes were detected in the present brain specimens, we examined host genes known to participate in responses to infections.

Now, in a study comparing mice raised in a «germ free» environment and mice raised under more typical lab conditions, scientists have identified yet another key role of the microbes that live within us: mediator of host gene expression through the epigenome, the chemical information that regulates which genes in cells are active.

We were able to show that, in addition to the nutrients that flow into dodder from the host plant across the haustoria, dodder passes microRNAs into its host plant that regulate the expression of host genes in a very direct way.»

«Gut's microbial community shown to influence host gene expression.»

They showed evidence for host gene - microbiota interactions contributing to disease risk in a mouse model of autoantibody - induced inflammatory skin disease.

In one study, Michael Levin, F.R.C.P.C.H., of Imperial College London, and colleagues investigated whether bacterial infection can be distinguished from other causes of fever in children by the pattern of host genes activated or suppressed in blood in response to the infection and whether a subset of these genes could be identified as the basis for a diagnostic test.

In this view, viruses are fugitive host genes that have degenerated into parasites.

They thrive in bodily fluids and tend to get copied several times into host gene sequences, which can wreak genetic havoc and sometimes lead to cancer.

Peeling back the complex interplay of genes, diet and the trillions of microorganisms that live in the guts of humans and other animals, Rey, Attie and their colleagues are beginning to work out the subtleties of how host genes shape the composition of the microbiome and contribute to an animal's phenotype and, ultimately, diet - induced metabolic disease.

«What was really interesting is that the microRNAs specifically target host genes that are involved in the plant's defense against the parasite.»

Profiling the expression patterns of host genes revealed that the insect significantly increases the abundance of B vitamin transporters and activation enzymes when reared in the absence of its gut microbes.

«The discovery presents virus evolution for us in new ways, vastly expanding our understanding of how many essential host genes viruses can capture during their evolution,» said National Institutes of Health evolutionary and computational biologist Eugene Koonin, a study co-author whose lab collaborated with DOE JGI on analyzing the Klosneuvirus genome.

(Viruses had long been considered to straddle the line between living and non-living things because of their extreme reliance on host genes.)

Early adaptations of the initial technology were used in functional genomics screens identifying host genes affecting HIV [2] and Trypanosome infection.

Changes in the Rumen Epithelial Microbiota and Host Gene Expression of Cattle in Response to Alterations in Dietary Carbohydrate Composition.Petri RM.

The parasite inserts microRNAs into the host that can silence the expression of host genes.

Secretory antibodies in breast milk promote long - term intestinal homeostasis by regulating the gut microbiota and host gene expression

Host genes of the major histocompatibility complex (the genes that determine how mammals respond to pathogens) play a significant role in how the immune system responds to all pathogens.

This complex mix of virus, host genes and tumor development may have relevance to a related human condition.

«One of these effectors mimics the host transcription factors, directly targeting and activating the host gene transcription of a plant sugar transporter.

Host gene expression and metabolism were also characterized.

Duke University researchers, with colleagues from UNC - Chapel Hill and Stanford, found that the host genes in the intestine are poised to respond to microbes, and the microbes signal to the host to determine which genes respond.

The two groups of offspring will differ only in whether they carry that gene, not in their resident microbes, allowing the influence of the host gene and the microbes to be disentangled.

Together, the three studies map the complicated interactions between viral and host genes, an accomplishment achieved for few other viruses to date.

In this rare cell line, Carette and co-workers generated mutations in almost all human genes and used this collection to screen for the host genes used by pathogens.

Resistance to Turnip Crinkle Virus in Arabidopsis Is Regulated by Two Host Genes and Is Salicylic Acid Dependent but NPR1, Ethylene, and Jasmonate Independent

The Keystone Symposia's annual meeting on HIV Vaccines, held jointly this year with a meeting on Viral Immunity and Host Gene Influence, kicked off March 21 in Keystone, Colorado, with a keynote about hepatitis A and hepatitis C that could well have been entitled, «A Tale of Two Viruses.»