Sentences with phrase «immune attack»

The same process, however, plays no role in maintaining immune balance or preventing the misguided immune attack on healthy tissue that leads to autoimmune problems, researchers reported.

The consequence of the dysfunctional immune attack is damage to small, hair - like projections that line the small intestine.

The immune system can, for example, dispatch «regulatory» cells that suppress immune attacks against self.

Melton said that the device Anderson and his colleagues at MIT are currently testing has thus far protected beta cells implanted in mice from immune attack for many months.

«Blood clotting protein triggers immune attack on brain: Disruption of the blood - brain barrier triggers a cascade of events that results in autoimmunity, brain damage characteristic of multiple sclerosis.»

Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

Antibodies are proteins that the body's immune system makes to fight a germ or to trigger another type of immune attack.

HIV notoriously dodges immune attack — and preventive vaccination — by mutating.

But in July, John Tisdale of the National Institutes of Health and his team reported that 26 of 30 adult sickle cell patients recovered after a far less grueling treatment: low - dose radiation, a partial bone - marrow transplant and an antibody to prevent immune attacks on the new marrow.

The microbes increased the kind of cells that activate immune attack (they're called T helper cells) and decreased the kind (regulatory T cells) that suppress excessive immune responses, including autoimmune attacks as in MS.

But if researchers can figure out how to train the immune system to tolerate transplants, the knowledge could have implications for the treatment of autoimmune diseases, which also result from unwanted immune attack — in these cases on some of the body's own tissues.

IMMUNE ATTACK Doctors can engineer a patient's own immune cells to kill cancer cells.

Part of the problem may be that an overly aggressive immune attack on artery - clogging plaque can worsen the situation, says Prediman Shah, director of cardiology at Cedars - Sinai Medical Center in Los Angeles.

Most teenagers have run - ins with their mothers, but little do they know that they already weathered a potentially fatal conflict within the womb: developing as essentially foreign tissue without triggering a hostile immune attack.

Moreover, the CLA supplementation dampened the injurious inflammation — an inappropriate immune attack — without impairing the animals» ability to produce antibodies or launch a healthy immune response to infection.

Orchestrating a successful immune attack against tumors has proven difficult so far, but a new study from MIT suggests that such therapies could be improved by simultaneously activating both arms of the immune system.

When deployed directly in mice with lupus or an acute flu infection, the polymers home in on the DNA and RNA refuse from dying cells, halting the damaging immune attack.

When we're sick, Kipnis proposes, it's more important to launch a powerful immune attack than to have a sharp mind.

«This study breaks new ground because it focuses on boosting beta cell performance and shows that beta cell preservation is possible even in the face of such immune attack,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and J.S. Simmons Professor of Genetics and Metabolism at HSPH.

He further showed that PD - L1 is highly expressed on many solid tumors such as breast and lung, as well as some hematologic malignancies, and allows these tumors to resist immune attack.

Malik Peiris of the University of Hong Kong found that antibodies to a vaccine made from the main surface protein of SARS allow the virus to enter immune cells, where they can trigger a destructive immune attack on the lung.

MD Anderson has more than 160 clinical trials open testing drugs and cellular therapies that stimulate and support immune attack against many different types of cancer.

We are recruiting people who have developed Type 1 Diabetes in the last 6 months to receive treatments which aim to reset the immune system and mobilize stem cells - hoping that will reverse or prevent further immune attack of pancreatic beta cells.

In particular hyphal forms cause disease, as these forms can efficiently evade host innate immune attack and as they attach to and invade human epithelial cells and cause further tissue damage.

I believe what happens is antibodies against food happen to be shaped so that they also bind to bodily tissues, launching a painful or disabling immune attack against your joints, your digestive system, or even your nervous system.

This is important: if the fetus had an ability to generate antibodies and mount an immune response, it might generate immune attacks against the mother leading to miscarriage.

I confess I don't wear great clothes, mostly because I gain a ton of weight whenever an auto - immune attack hits and more if I go on prednisone.

This also gives them an unique antigenic signal allowing very specific immune attack upon them.

Infections can trigger immune attacks on kids» brains, provoking devastating psychiatric disorders.

An emerging approach to treating disease combines living cells with plastic membranes that shield the cells from immune attack

The new «trivalent» vaccine induces antibodies against three different parts of the virus, including two components that normally help HSV2 evade immune attack.

The bacterium that causes stomach ulcers morphs at a breakneck pace when it first infects a person, apparently to dodge immune attack, researchers report June 13 in Nature Communications.

In the body, MHCI proteins are watchdogs, tagging infected cells for immune attack.

An experimental vaccine given to monkeys triggered a lasting immune attack that eliminated all traces of an AIDS - causing virus after a year or more.

«Toxoplasma infection leads to massive changes in the host cell to prevent immune attack and enable it to acquire a steady nutrient supply,» Dr Tonkin said.

«Partnering cells turn off immune attack on pancreatic tumors.»

Perhaps her body sees them as foreign and mounts an immune attack, which might alter certain structures of the male brain.

To take root and grow, a tumor must evolve mechanisms over months or years to evade immune attack.

«The multiple sclerosis drugs currently on the market and being tested elsewhere seek to reduce the immune attack on cells, but none target neurodegeneration nor do they work to restore nerve cell function.

There was another intriguing connection: Acinetobacter are molecular mimics of proteins found in myelin, the nerve cell coating that the immune system attacks in MS.. That suggests the bacteria might trigger immune attacks that hit myelin, too, as when soldiers who inadvertently resemble the enemy get hit by friendly fire.

CANCER»S SWEET CLOAK Large surface proteins with chains of sugars (illustrated, yellow) on the outside of a cancer cell hide the tumor from immune attack and lull the immune system into a do - nothing trance.

This helps the worm ensure that it will be picked up and transmitted by another mosquito despite the immune attack (PLoS Biology, DOI: 10.1371 / journal.pbio.1000525).

What causes the initial nerve damage or incites the immune attack is still a big question.

But the problem may be that the organelles can not keep up with the energy demand of the cell as it tries to fend off an immune attack.

And, if the immune attack comes first, as Dutta and Lublin suspect, what is the trigger?

«In essence, we're stimulating the immune system to attack the virus and at the same time preventing the virus from using some of the tools it has to thwart that immune attack,» Friedman said.

Tumors typically have a repertoire of molecular defenses they can use to suppress or evade immune attacks, which is why cancer vaccines and immunotherapies have had mixed results in clinical trials to date.

In the hunt for genetic and environmental factors responsible for allergies, a prime suspect has been interleukin - 4 (IL - 4); this immune system protein tells white blood cells to make IgE antibodies, which recognize foreign substances and set off an immune attack.