Sentences with phrase «of the genome»

Now, the researchers are able to reliably detect and quantify so - called «three - way contacts» in regions of the genome that are vigorously expressed.

The lab creates widely used software and databases, performs applied analyses of genome sequences, and partners with diverse research teams on projects at the intersection of the computational and life sciences.

In addition to the direct results obtained, this analysis has allowed us to develop and test methods that will be needed to interpret the complete sequence of the genome of this species.

They found snippets, about 2 percent of the genome in total, that seem out of place in human DNA.

Because the mutations were detected in the poorly understood portions of the genome called junk DNA, nobody knows for sure what the impact may be.

Human reproductive applications are probably the most talked about potential application of genome editing technologies and raise some of the most complex ethical concerns.

That enabled the scientists to get roughly 85 percent of the genome in the right place.

A genetic study has found areas of the genome linked with the age at which people have sex for the first time.

However, the widespread availability and use of genome sequencing in the practice of clinical medicine is imminent.

They then examined patterns of genetic variation and evolutionary change in those regions relative to the rest of the genome at an unprecedented level of detail.

The team used a computer program to predict the outer shape of a genome from its base pairs.

Third, the lab engages in the applied analysis of genomes for pediatric disorders, in part to improve the delivery of information to clinicians.

Researchers would need to choose an appropriate cell line to act as a host and then gradually swap out large chunks of its genome with the synthetic DNA.

The bug has not one, but four copies of its genome in separate compartments.

And now we have our best - ever view of African genetic diversity, with the publication of a huge study of the genomes of people from across the continent.

The researchers started by examining sets of genome data on more than 250,000 people, of South Asian, East Asian or European descent.

What's behind his claims about the value of genome research and his plan to combat climate change?

A bigger surprise came from analysis of the genetic sequences, which revealed that these genes made up a mere 1.5 per cent of the genome.

The average size of the genome fragments was 800 times larger with approximately 90 percent of all gaps in the original assembly closed.

You require no previous knowledge of genome science to complete the course.

These processes are important to maintain the integrity of our genome which is crucial to prevent genetic diseases such as cancer.

Indeed, new and more efficient strategies are needed to make sense of the data coming out of genome projects.

We have found two regions of the genome where error - prone genes lie and have narrowed the first region to a few hundred bases in an interval that has only two genes.

But exactly how these slight changes to the modern human sequence affected the functioning of these genome regions remains to be determined.

This consortium selected 44 separate sections of the genome that included regions of high to low gene density and high to low similarity between mouse and human.

It gives good new insights into the outbreak such as the predicted introduction time, although the number of genomes reported is very small.

Other concerns include data storage, the quality of sequencing data and the accuracy of genome assembly.

The meeting identified immediate steps to take toward ensuring that the application of genome engineering technology is performed safely and ethically.

We expanded on our genome sequencing efforts to include efforts in whole genome gene expression analysis and functional analysis of genome variation.

The mapping of the genome was finished in 2003, and scientists are continuing on the quest to discover what each gene does and how it functions.

«We used most of the genome sequence of a known species, so it had a reasonable chance of working,» he said.

Now, a new, extensive comparison of the genomes of polar bears and their closest relative, the brown bear, has revealed how polar bears survive such unhealthy diets.

With the recent decreasing cost of genome sequence data, there has been increasing interest in rare variants and methods to detect their association to disease.

They expect to receive an improved version of the genome this summer.

The technique offers, through high - level editing operation, a method to address the existing issues of genome editing.

Therefore, the role of genome structure on widespread DNA gain and loss and its subsequent impact on lineage - specific species evolution remains unknown.

About one - third of respondents listed the field's lack of basic understanding of genome biology as one of the main obstacles to making use of sequence data today.

Seven of those regions were found in parts of the genome known to play a role in characteristics of our skin.

At the moment, the region of the genome containing the genetic mutation has been identified.

This activation is achieved by proteins called epigenetic regulators, which work to make specific regions of our genome more or less accessible to transcription.

And because humans and flies share much of their genomes, studying the insect's sleep and memory may allow us to finally understand our own.

Studies over the past decade have revealed that the complexity of the genome, and indeed almost every aspect of human biology, is far greater than was previously thought.

We specifically chose genomic features that could be found in both genomes as indicators for distinct aspects of genome biology.

They particularly support the interpretation of genome sequence data, which has become a powerful tool in many areas of biology and medicine in the last years.

The DNA repair machinery is vital for the maintenance of genome integrity and for the proper function and survival of all organisms.

This will include a summary detailing the data that have been generated and key features of the genome identified from genomic assembly and clone mapping / sequencing.

We know two - thirds of the genome of one of them.