Sentences with phrase «other animal models»

They also stopped making new brain cells, something that has also been seen in other animal models of depression.
Researchers are, however, continuing to explore microbiome interactions using other animal models.
Additionally, the wheel lock and other animal model suggest that exercise during youth may help preserve muscle mass over the course of aging and lower the activity of genes associated with cardiovascular disease.
Here we used our knowledge of the developmental biology of many other animal models to provide the positive and negative signaling factors to guide the developmental choices of these tissue and organ stem cells.
The team now plans to test out the nanoparticles in other animal models with a view to moving to human clinical trials.
They found that, within the first three days of injury, fish in the concussion group were slower to find a school of fish with which they previously swam, a measure of spatial memory which is impaired in other animal models of concussion and human patients.
And the trouble with extrapolating so much from mouse studies is that «nobody has actually shown over the long term how long these quote un-quote improvements persist, and we don't know whether it's broadly improving aspects of aging or it's specific to certain tissues,» said Matt Kaeberlein, a biologist who studies aging in dogs and other animal models at the University of Washington.
Scientists need other animal models as well, and major breakthroughs have been made and are in the process of being made thanks to studies conducted with these animals:
«Thus it seems that outside of [genetically engineered mice or a cell culture dish or other animal models] that the search for the true role of the growth potential for IGF - 1 in adult muscle hypertrophy is a vain one.»
However, data from other animal models demonstrate diminished lysosomal enzyme activity during extended periods of energy restriction (39).
This proposed role for GM1 (and indirectly GD1a) provides a rationale for its potency in suppressing diabetes in NOD mice (10) and disease onset in other animal models of autoimmunity.
After discussing similar effects in other animal models of cancer and a few studies showing the ability of antioxidants to prevent cancer growth, Campbell concluded that «a pattern was beginning to emerge: nutrients from animal foods increased tumor development while nutrients from plant - based foods decreased tumor development.»
We only showed it in mice, so one has to extend this to other animal models — the ferret and the guinea pig.
«Given prior work in other animal models it is not surprising that the vaccine protects monkeys from lethal challenge with Nipah virus.
The researchers now plan to test this type of insulin in other animal models and are also working on tweaking the chemical composition of the insulin to make it even more responsive to blood - glucose levels.
«Usually, when researchers want a mouse or other animal model to express fluorescent proteins in certain cells, they need to develop genetically modified animals that can take months to years to make and characterize,» says former graduate student and first author Ken Chan (PhD» 17).
If the findings of the study are replicated in other animal models, such as pigs, they could have considerable implications for public health, says Oluf Pedersen, professor of genomic medicine at the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen.
«We will eventually negotiate a path to getting permits for highly innovative projects where there is no other animal model available,» he says.
Also, research in other animal models, such as rodents, has shown anesthesia exposure early in life can lead to cell death in the brain and cognitive impairments.
A cancer drug that has shown promise against Alzheimer's disease (AD) in mice and has begun early clinical trials has yielded perplexing results in a novel mouse model of AD that mimics the genetics and pathology of the human disease more closely than any other animal model.
In the case of influenza, mAbs have been shown to provide prophylactic or therapeutic protection in mice and other animal models (Reuman et al., 1983; Sweet et al., 1987; Palladino et al., 1995; Renegar et al., 2004).
Other animal models either express oncogenes in a tissue - specific manner or shut down the expression of tumor suppressor genes in the whole tissue.
While the majority of this research is conducted with rodents that are bred specifically for research, other animal models are essential to study specific diseases because of their biological and physiological makeup.
Thus, the analytical tools developed by the Schroeder lab to identify structures and functions of biogenic small molecules will be transferable to other animal models.
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