Sentences with phrase «pathway analysis»
Pathway analysis refers to the process of studying and understanding the different pathways or series of interactions that occur within a biological system. It helps in identifying the key molecules, genes, or proteins involved in a particular pathway and how they interact with each other. By analyzing these pathways, scientists can gain insights into the causes, effects, and relationships between different components, which can be useful for understanding complex biological processes or diseases. Full definition
By the end of 2009, I was involved heavily in pathway analysis of the array data.
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He says the EEG and fMRI techniques «counter each other's weaknesses» in pathway analysis.
They whittled a 1,597 gene dataset down to 360 MD suspects, which went through a knowledge - based pathway analysis using IPA.
Illustrative example of pathway analysis with respect to axonal guidance pathways.
A number of fancy clinical - correlation and pathway analyses revealed some interesting patterns of somatic mutations between AI - sensitive and AI - resistant tumors:
In addition, we performed a preliminary pathway analysis [12] using these data, to examine the feasibility of this type of tool for future investigations to probe for clues to the pathogenetic mechanisms behind these diseases.
The Moores Cancer Center's Molecular Tumor Board brought together medical, surgical and radiation therapy oncologists, biostatisticians, radiologists, pathologists, clinical geneticists, basic and translational science researchers, and bioinformatics and pathway analysis specialists to discuss the intricacies of tumor genetics and tailor a personalized treatment plan for patients with advanced cancer or who have exhausted standard therapies.
A proteomics analysis revealed expression changes of 56 proteins, and a further protein pathway analysis suggested their association with the cell morphology, the organization, and the increased cellular movement and the proliferation.
S2 A and B and S3 A and B) and visualized by Cytoscape pathway analysis (SI Appendix, Fig.
The annual meeting will have a symposium on lipid signaling and metabolism, at which JLR Associate Editor Michael Wakelam of the Babraham Institute will give a talk on using lipidomics pathway analysis to identify therapeutic targets.
Using these orthogonal measures of cellular pathway analysis, we confirmed that HPP - 4382, in contrast to bardoxolone, did not induce significant cellular stress at high doses as measured by HSPA6 expression and that the mechanism of HPP - 4382 activity does not appear dependent on NF - B as ICAM1 expression is not induced by HPP - 4382 (data not shown).
Koschmann, J., Bhar, A., Stegmaier, P., Kel, A. E. and Wingender, E. Upstream Analysis: An integrated promoter - pathway analysis approach to causal interpretation of microarray data.
We first performed pooled sample analysis, then individual sample analysis, and then pathway analysis using the observed proteins.
Both have been included in the recent Deep Decarbonization Pathways analysis undertaken by one of the sponsors of today's meeting, the U.N. Sustainable Development Solutions Network.
We also used the Ingenuity Pathway Analysis software to determine which, if any, gene functions were significantly enriched with genes whose differential promoter methylation levels were associated with chronic aggression.
All functional analysis was done using Ingenuity Pathway Analysis with the default parameters as it was shown to be a reliable approach to identify biological pathways that influence disease outcomes [52].
Pathway analysis revealed that the differentially expressed miRNAs were involved in potential glaucoma pathways, including focal adhesion, tight junctions and TGF - beta signaling.
Pathway analyses implicate glial cells in schizophrenia.
The ECETOC Young Scientist Award at the European Societies of Toxicology (Eurotox) Annual Congress (Rhodes, Greece, 5 - 8 October 2008) went to: Ms Nathalie Lambrecht of CARDAM VITO in Belgium for her poster, entitled «Pathway analysis of dendritic cell markers for skin sensitization.»
That requires analytical and bioinformatics tools to conduct disease or therapeutic association and pathway analysis that combines various forms of «omics data.
The dominant finding from the pathway analysis was that sphingolipid abnormalities constituted close to 50 % of all of the metabolic disturbances associated with CFS in both males and females.
ioinformatics, statistics, pathway analysis, and / or assistance preparing materials for manuscripts or presentations.
His specialities include computational biology, bioinformatics, data mining, text - mining, pathway analysis, and genomics.
Perspectives: Pathway analysis of PRDM16 shows that it is a very attractive candidate as a key regulator for cardiac hypertrophy and and remodeling.
Pathway analysis revealed that cold upregulated pathways involved in energy usage, oxidative phosphorylation, and fatty acid β - oxidation to a similar extent in wildtype and PPARα − / − mice.
193/6: 30 The hunt for rare disease diagnosis: Utilization of social media, model organisms, and pathway analysis in pediatric exome sequencing.
The research employed associational methodology and used Structured Equation Modeling statistics, specifically, Pathways Analysis, to analyze a variety of variables and their relative influence upon mathematics achievement for the fourth - and eighth - grade NAEP scores.
Dr. Patrinos highlighted advances in genomics, structural biology, pathway analysis, and systems biology as driving forces in the move toward molecule - based cell simulation.