Sentences with phrase «plasma concentrations»
"Plasma concentrations" refers to the amount or level of a substance that is present in the liquid part of the blood, called plasma. Full definition
This is the most effective delivery method, because it allows plasma concentrations of the vitamin to reach levels high enough to potentially kill cancer cells and offer other benefits.
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«CHO [carbohydrate] and CHO+VC significantly blunted the post-exercise increase in plasma concentrations of cortisol, ACTH, total leukocyte, and neutrophil counts and limited the decrease in plasma glucose concentration and bacteria - stimulated neutrophil degranulation.»
* Clinical research shows that Meriva supplementation results in higher plasma concentrations of curcumin from a much smaller amount than with ordinary curcumin.
Meanwhile, this study found that «patients with severe acne had significantly lower plasma concentrations of vitamins A and E than did those with lower acne grade and the age - matched healthy controls».
In another controlled feeding trial, a higher percentage of energy from TFAs increased plasma concentrations of CRP, IL - 6, and E-selectin (7).
The drop in blood pressure was associated with the highest blood plasma concentration of phenolic compounds, particularly vanillic acid and protocatechuic acid.
In conclusion, we found that, in apparently healthy women, dietary magnesium intake was inversely associated with plasma concentrations of CRP and E-selectin but not with those of IL - 6, sTNF - R2, sICAM - 1, or sVCAM - 1.
It is orally bioavailable and reaches peak plasma concentrations in 1 hr in dogs; it has an elimination half - life of 24 hr because of enterohepatic recirculation.
Conclusions / significance: These results suggest that a single dose of 0.2 mg / kg ERB is safe, provides consistent therapeutic plasma concentrations, and exhibits prolonged analgesia in healthy dogs.
Using a dose chosen for each compound individually based on the clinically relevant maximum plasma concentration, the scientists found a strong synergistic interaction between flutamide, a drug approved for the treatment of prostate cancer, and phenprocoumon (PPC), an anti-thrombosis compound.
Indeed it did, with CSF concentrations reaching about 0.3 % of plasma concentrations at any given dose of the antibody.
Indeed, babies fed higher levels of breast milk show higher plasma concentration levels of DHA and AA in the brain cortex, cerebral grey and white matter, as well as a higher IQ up to 15 years of age compared to babies fed formula not containing LCPUFA.
This older study demonstrates similar effects of diallyl disulfide (the major liver metabolite of allicin from garlic) in inhibiting inflammatory cytokine expression, at plausible plasma concentrations.
Patients may have normal plasma concentration of magnesium yet have depleted intracellular stores [31].
Zinc supplementation restores plasma concentrations of zinc and thymulin in patients with Crohn's disease.
Mean plasma concentrations of total and sex - hormone - binding - globulin (SHBG)- bound testosterone were 13 % and 15 % higher, respectively, on the high - fat, low - fiber diet and the difference from the low - fat, high - fiber diet was significant for the SHBG - bound fraction (P = 0.04).
ITRAFUNGOL is a cytochrome p - 450 inhibitor and may increase or prolong plasma concentrations of other drugs metabolized by this pathway.
Peterson ME, Kemppainen RK: Dose - response relationship between plasma concentrations of corticotropin and cortisol after administration of incremental doses of cosyntropin for corticotropin stimulation testing in cats.
Lopinavir Plasma Concentrations and Serum Lipids in Therapy Naïve HIV - Patients: A Sub Analysis of the FREE Study
The maximal plasma concentration of levonorgestrel (approximately 40 nmol / l) is reached within 3 hours.
We found that higher intakes of non-HVOs are independently associated with lower plasma concentrations of some inflammatory markers.
Peterson ME, Kemppainen, RJ, Orth DN: Effects of synthetic ovine corticotropin - releasing hormone on plasma concentrations of immunoreactive adrenocorticotropin (ACTH), alpha - melanocyte - stimulating hormone (αMSH), and cortisol in dogs with spontaneous adrenocortical insufficiency.
Bioavailability determinations based on the peak plasma concentration can be misleading, because drug elimination begins as soon as the drug enters the bloodstream.
Therapeutic plasma concentrations (> 1 ng / mL) occurred from 0.5 to 72 hours after administration in most (5/6) dogs.
We found a significantly increased plasma NO concentration after SMR and others have suggested that NO participates in the regulation of arterial stiffness (25,30).
Results: Maximum plasma concentrations (median, range) of buprenorphine in dogs receiving ERB was 5 (4.3 - 11.0) ng / mL, which occurred at 8 (4 - 36) hours (Tmax).
Age variation of the 24 - hour mean plasma concentrations of androgens, estrogens, and gonadotropins in normal adult men.
The second study reports no differences in plasma concentrations of amyloid - β peptides among young adult ɛ4, ɛ3 or ɛ2 carriers.
Conclusions: Higher intakes of PHVOs are associated with elevated concentrations of inflammatory biomarkers, whereas higher intakes of non-HVOs are associated with lower plasma concentrations of these biomarkers.
The plasma concentration of pethidine in the infant is almost as high as that in the mother, reaching a maximum after 2 - 3 hours, after which the level falls slowly.
Blood plasma concentrations of naloxone were measured nineteen times for each volunteer during each treatment session, with intense sampling in the first 15 minutes after dosing.
«A higher plasma concentration of these proteins means that there has been greater damage of muscle fibres and, therefore, a greater probability of fatigue.