Sentences with word «synthetase»

When prompted, fragments of a tRNA synthetase come together and charge a tRNA with a bio-orthogonal amino acid (N3), which is inserted as a recognizable tag into all subsequent proteins made in the cell.

«In healthy subjects, it seems that the level of asparagine synthetase in the brain is sufficient to supply neurons,» Michaud said.

Eid T, Thomas MJ, Spencer DD, Runden - Pran E, Lai JC, Malthankar GV, Kim JH, Danbolt NC, Ottersen OP, de Lanerolle NC (2004) Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy.

In addition to glycolysis, acetyl - CoA is produced from the oxidation of fatty acids by acyl - CoA synthetase enzymes in the outer mitochondrial membrane, and then transported into the inner mitochondrial matrix by acetyl L - carnitine for β oxidation and ATP production.

The other, called carotone synthetase 1, came from the soil bacterium, Erwinia uredovora.

Some of the other active enzymes include diastase, lactose synthetase, and lactoperoxidase.

The whole fumisoquin biosynthetic pathway appears to be a combination of plant biosynthetic principles and the non-ribosomal peptide synthetases commonly found in fungi.

One of these genes codes for the enzyme acetyl - CoA synthetase, which helps regulate both fatty acid synthesis and ethanol detoxification.

While the active anti-inflammatory effects of ginger are due to the inhibition of PH synthetase by gingerols, shogaols, and zingerones, turmeric's most significant active compounds are turmerone and curcumin.

Do a search on how the Hemoglobine works... or the ATP Synthetase works....

When prompted, the tRNA synthetase charges a tRNA with the bio-orthogonal amino acid, which is then used by ribosomes to insert the tag into proteins made in the cell.

The alanyl aminoacyl transfer RNA (tRNA) synthetase recognizes the exocyclic amine of an invariant G.U pair and contacts a similar array of 2» - hydroxyls when binding the tRNA (Ala) acceptor stem, providing an unanticipated parallel between protein - RNA and RNA - RNA interactions.

Nakagawa T, Lomb DJ, Haigis MC, Guarente L. SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.

Glutathione was measured in NHLF cells following a 4 - hour treatment with buthionine sulphoximine (BSO, an inhibitor of gamma - glutamylcysteine synthetase), electrophilic compounds including bardoxolone, sulforaphane and HPP - 1014, and non-electrophilic compounds, including CoPP and HPP - 4382.

Single nucleotide polymorphisms in genes for 2» -5» - oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection.J Infect Dis.

BMAA has been demonstrated to be concentrated in the brains of ALS patients (but not controls) in Florida [19] and to be mis - incorporated into neuronal proteins via the L - serine tRNA - synthetase system [20 — 22].

The genes encoding the variable domains were individually inserted on to the human IgG1 heavy and light chains by splice - overlap PCR using the anti-CEA hT84.66 - M5A antibody as a template and cloned into glutamine synthetase vectors (Lonza Biologics, Slough, UK) as previously described [21].

In order for this activation to take place, the enzyme methionine adenosyltransferase (MAT, also known as S - adenosyl methionine synthetase) breaks apart ATP to harvest from it a molecule of adenosine and then activates methionine by sticking adenosine onto it.

«Glycogen Synthetase Activity in Skeletal Muscle: Interconversion of Two Forms and Control of Glycogen Synthesis.»

The mutation for an altered form of the acetohydroxyacid synthetase gene was provoked and selected, making this strain of wheat resistant to the herbicide Beyond, or imizamox, allowing the farmer to spray the herbicide freely, killing weeds (and soil microbiota) but not the wheat.

Stevia First owns the patent on steviol synthetase, an enzyme that can boost the production of steviol glycosides without any bitter aftertaste.

Watari T, Kaneshima T, Tsujimoto H, Ono K, Hasegawa A. 1998 Effect of thromboxane synthetase inhibitor on feline infectious peritonitis in cats.

Production of the enzyme asparagine synthetase is deficient in ALL and several other types of cancer cells, which are therefore unable to synthesize the amino acid asparagine.

Tony Wilkinson trained for his PhD with Alan Fersht at Imperial College London working in protein engineering on tyrosyl tRNA synthetase.

Many of the genes known to be directly transactivated by the overexpression of the transcription co-factor HIF - 1α were identified, and included inducible nitric oxide synthetase 2, insulin - like growth factor 1, insulin - like growth factor binding protein 2, and hexokinase 2.

The other, called carotone synthetase 1, came from the soil bacterium, Erwinia uredovora.

As mentioned previously, ginger properties include anti-inflammatory actions that stem from a group of compounds called gingerols, which work by inhibiting the prostaglandin - biosynthesizing enzyme, known as PH synthetase or cyclooxygenase (COX).

In fact, most differentiated cells use glutamine synthetase to bind excess ammonia to form glutamine [104].

Terry: Glutathione synthetase is stimulated by [brassica 00:46:41] vegetables, vegetables in the cabbage family, in the onion family.

Human milk contains various enzymes; some are specific for the biosynthesis of milk in the mammary gland (eg, lactose synthetase, fatty acid synthetase, thioesterase), whereas others are specific for the digestion of proteins, fats, and carbohydrates that facilitate the infant's ability to break down food and to absorb human milk.

The researchers also found that metastasis was greatly limited by reducing asparagine synthetase, treatment with the chemotherapy drug L - asparaginase, or dietary restriction.

The researchers discovered that the appearance of asparagine synthetase — the enzyme cells used to make asparagine — in a primary tumor was strongly associated with later cancer spread.

The Rice lab's breakthrough was the discovery of a tRNA synthetase that only adds the amino acid to the tRNA when it binds a chemical.

Fournier started with two related proteins, TrpRS (tryptophanyl tRNA synthetase) and TyrRS (tyrosyl tRNA synthetase), which help decode RNA letters into the amino acids tryptophan and tyrosine.

The mutated gene turned out to encode a protein whose sequence suggests it is an acyl coenzyme A (CoA) synthetase, an enzyme that helps break down fatty acids.

The plant rids itself of the toxic ammonia with an enzyme called glutamine synthetase.

There are 20 of these ancient enzymes called aminoacyl - tRNA synthetases (aaRSs).

The team identified the gene affected by the mutation code for asparagine synthetase, the enzyme responsible for synthesizing the amino acid asparagine.

And legume - grown tomato leaves expressed higher levels of nitrogen uptake genes, such as rubisco and glutamine synthetase, and defense genes, such as chitinase and osmotin, the authors report online this week in the Proceedings of the National Academy of Sciences.

«We have found that the plant receptor binding BABA is an «aspartyl tRNA synthetase» which we have called IBI1.

Schmied WH, Elsässer SJ, Uttamapinant C, Chin JW, «Optimized Pyrrolysyl tRNA synthetase / tRNA expression and engineered eRF1 enable efficient multi-site unnatural amino acid incorporation in mammalian cells ``, JACS, (2014)