Sentences with phrase «cellular genes»
Because the pathophysiology of cancer is linked to alteration of cellular gene expression, the bioinformatics toolbox promises to offer countless molecular insights into mechanisms, diagnostics, and new medical interventions for cancer.
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To do this, the scientists based their sequence inputs on microRNA, small RNA molecules that regulate cellular gene expression.
Dr. Verma's major research interests are cellular genes whose alteration can cause cancer and the development of techniques for gene therapy.
A major problem is toxicity: impeding either may not only activate latent virus, but also a whole lot of other cellular genes leading to symptoms like those seen in the side effects of cancer chemotherapy.
This so - called microRNA disrupts the expression of two key cellular genes called TGF - β and SMAD3, in a process known as RNA interference (RNAi).
How cellular gene regulatory networks (GRNs) respond to the morphogen, in a concentration - dependent manner, is a pivotal question in developmental biology.
Similar to latently infected CD4 + T cells, the J - Lat cells harbor a full - length HIV - 1 genome that is transcriptionally competent, is integrated within actively transcribed cellular genes, and is inhibited at the transcriptional level.
With these tools, Verma is revealing how the aberrant expression of normal cellular genes can causes tumors.
On the other hand, using near - term nanotechnology to deliver into cancer cells siRNA or miRNA to alter cellular gene expression might also make it possible to «repair cancerous cells».
In addition to gene therapy technologies, Dr Verma's major research interests are cellular genes whose alteration can cause or suppress cancer.
To account for the remarkable similarity between retrovirus oncogenes and their normal cellular kin, most virologists have settled on the idea that retrovirus oncogenes are copies of cellular genes.
It is a cellular gene, which is now called c - src.
«In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on system allows activation of cellular genes.
Mobile DNAs in rice carry fragments of more than 1000 cellular genes.