Sentences with word «humoral»

While working at AFRIMS for 3 years, she trained scientists and students and worked on evaluation of humoral responses in several clinical trials, including two phase I / II prime - boost trials, in preparation for the RV144 phase III trial in Thailand.

The exact composition of germline V gene sequences in an individual has been difficult to determine due to the highly repetitive nature of the genomic sequences encoding these segments, thus limiting our understanding of humoral immune responses.

Our data indicate that 3 of 16 patients mounted a vaccine - specific humoral immune response.

(1991) «The role of humoral factors of regenerating liver in the development of experimental tumours and the effect of Rhodiola rosea extract on this process» Neoplasma; 38 (3): 323 - 31

Nolan's works begin with the close scrutiny of individual literary or artistic works, or evolve out of consciously erratic enquiries into the aesthetics of diverse fields, such as cosmology, humoral theory, and illuminated manuscripts.

In that study, only 1 of 12 patients had an anti-Id specific humoral response.

This hypothesis was later disproved by Cuche et al (25), who observed the involvement of a clear humoral mechanism in SCFA action by using innervated and denervated ileal loops in pigs.

Evaluation of the ability of canarypox - vectored equine influenza virus vaccines to induce humoral immune responses against canine influenza viruses in dogs.

Dose Selection for an Adjuvanted Respiratory Syncytial Virus F Protein Vaccine for Older Adults Based on Humoral and Cellular Immune Responses.

The Vaccine & Immunotherapy Center brings together many outstanding researchers within the Institute to focus on new immune based approaches to induce protective tumor immunity, to control the tumor microenvironment, and to use humoral and cellular immunity to control or eliminate cancer.

Recent studies identified sugar - and lipid - sensitive humoral signals secreted by the fat body, Unpaired 2 and CCHamide - 2 [14,15].

CCII's properties can suppress pro-inflammatory activity to reduce joint discomfort and restore cartilage health.1 CCII from chicken sternal cartilage was shown to reduce chronic joint inflammation by helping to regulate humoral and cellular immune systems.

In fact the presence of good humoral antibody levels blocks the anamnestic response to vaccine boosters just as maternal antibody blocks the response in some young animals.»

Deficiency of these compounds impairs both humoral as well as cell - mediated immunity.

In the higher organisms, including man, a complex set of neural and humoral regulatory mechanisms preserve the stability of the metabolic processes within very narrow limits, despite substantial changes in the external environment.

Under this rubric, several important areas were covered, including fetal development, membrane proteins, nutrient and humoral transporters, and signal transduction.

During his postdoctoral training at the California Institute of Technology, he developed Vectored ImmunoProphylaxis (VIP) as a means of engineering humoral immunity, leading to successful demonstration of this approach as a prophylaxis against HIV as well as influenza.

Poliovirus - specific CD4 + Th1 clones with both cytotoxic and helper activity mediate protective humoral immunity against a lethal poliovirus infection in transgenic mice expressing the human poliovirus receptor.

The fat body senses the concentration of intracellular amino acids through the activity of the Target of Rapamycin (TOR) signaling pathway, which in turn regulates the synthesis and secretion of an undescribed humoral factor (s), called the fat - body — derived signal.

The fat body senses intracellular amino acids through Target of Rapamycin (TOR) signaling, and produces an unidentified humoral factor (s) to regulate insulin - like peptide (ILP) synthesis and / or secretion in the insulin - producing cells.

Although much is known regarding the specificity and efficacy of antibody responses, our knowledge of the function, phenotype, and specificity of the antigen - specific B cells that are responsible for antibody production, as well as for long - term humoral memory, is inadequate.

Odunsi K, Qian F, Matsuzaki J, Mhawech - Fauceglia P, Andrews C, Hoffman EW, Pan L. Ritter G, Villella J, Thomas B, Rodabaugh K, Lele S, Shrikant P, Old LJ, Gnjatic S. (2007) Vaccination with an NY - ESO - 1 peptide of HLA class I / II specificities induces integrated humoral and T cell responses in ovarian cancer.

In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE.

Immunization with different Pf AMA1 alleles in sequence induces clonal imprint humoral responses that are similar to responses induced by the same alleles as a vaccine cocktail in rabbits.

For example, previous studies reported that only 23 % of immune sera examined contained specific serum IgG antibodies against PFA0135w, suggesting that this protein does not normally elicit strong humoral responses [59].

Kunze R., Ransberger K., et at: Humoral immunomodulatory capasity of proteases in immune complex decomposition and formation.

This allows the vaccine to mimic natural infection, while taking advantage of the cat's entire immune system and prompting a broad humoral and cell - mediated response.

Elbow dysplasia is a combination of four developmental abnormalities: an ununited anconeal process, osteochondrodystrophy (OCD) of the distal humoral condyle, a fragmented medial coronoid process, and elbow incongruity.

The effect of emotional stress on the primary humoral immunity of rats.

The development of CMI is the most crucial factor in determining the ultimate outcome of FIPV infection.4, 5,12 Cats that produce humoral antibodies but fail to generate an effective CMI response develop effusive FIP.4, 5 Experimental evidence demonstrates that cats with non-effusive FIP often have preceding, transient effusive disease.4 Thus, noneffusive FIP is believed to result from a partially protective CMI response that is unable to wall off and contain the virus.4

Determination of serum antibody titers is one method commonly used to assess host humoral immune responses to a number of disease - causing organisms.

Nolan's works evolve out of consciously erratic investigations into the aesthetics of diverse fields such as cosmology, humoral theory and illuminated manuscripts.