Sentences with word «necrosis»

TIA - 1 and TIAR are related proteins that bind to an AU - rich element (ARE) in the 3» untranslated region of tumor necrosis factor alpha (TNF - alpha) transcripts.

Bruce Beutler and Anthony Cerami provide the first demonstration of the role of tumor necrosis factor in the pathogenesis of disease.

Jankovits DA, Liska WD, Kalis RH: Treatment of avascular necrosis of the femoral head in small dogs with micro total hip replacement.

The scientists found that feeding the rats fluoride substantially increased levels of two pro-inflammatory cytokines called tumour necrosis factor alpha (TNF - a) and resistin.

Legg - Calve - Perthes disease is also known as avascular necrosis of the femoral head.

It was hypothesized that silver toxicity, as manifested by liver necrosis in laboratory rats, was due to silver induced inhibition of the synthesis of the seleno - enzyme glutathione peroxidase.

In Lyme, white blood cells that attack germs produce inflammatory cytokines like interleukin - 6 and tissue necrosis factor alpha.

A lack of blood circulation within the stomach causes necrosis of stomach tissue, and changes within the bloodstream cause results in other derangements in the body.

Capsaicin was reported to cause a burning sensation and skin irritation when applied topically and to induce the erosion of gastric mucosa and hepatic necrosis when administrated in large amounts (48).

After the fact, sometimes as long as two years later, an injury can cause fat necrosis, which appears as a thickening or lumpiness in the breast.

Larger ingestions can result in acute liver necrosis and liver failure.

Legg Perthes Disease, also known as aseptic necrosis of the femoral head, Legg - Calve - Perthes Disease, Perthes Disease or simply Legg's Disease, is a condition that involves spontaneous disintegration and collapse of the top of a dog's long thigh bone, the femur, which connects the knee to the hip.

The disease is characterized by necrosis of the brain and clinical signs such as seizures, visual problems, trouble walking and difficulty eating, usually appear at 2 - 7 months of age.

If gastric necrosis and perforation occurs, euthanasia should be seriously considered.

Picture B shows an infected neurosphere with evidence of a nucleus undergoing necrosis and swollen mitochondria.

Take charge of five unique heroes that battle their way through various arenas to defeat Count Necrosis.

It is also common to see evidence of ischemic necrosis from vascular thrombosis.

The immune system removes dead brain tissue after a stroke by a process known as liquefactive necrosis, but the pathophysiology of this process is largely unknown.

Inflammation subsided in the children who had been treated with anti-tumor necrosis factor drugs (TNF inhibitors).

Affected animals» kidneys «demonstrating acute tubular necrosis in the kidney with intratubular crystals.»

These are full - thickness skin necrosis with subsequent loss of large areas of skin.

The present study revealed that juvenile aseptic bone necrosis — a disorder in which poor blood supply leads to bone damage — might have rendered Tut particularly vulnerable to physical injuries.

Duke researchers showed that these renal cancer cells remain healthy when all nutrients are present (left panel), but quickly swell up and die of necrosis when deprived of the amino acid nutrient, cystine (right panel).

A critical next step for this work is to understand how senescent changes in late life trigger such destructive waves of cellular necrosis.

On post mortem, pups have areas of focal necrosis on liver, spleen, lungs and kidneys.

Skin irritations can occur, or an even worse condition called Pressure Necrosis, which is a devitalization of the skin (similar to bed sores) due to excessive and prolonged contact against training collar probes.

Hepatic and biliary diseases including lipidosis, acute hepatitis / hepatocellular necrosis, cholangiohepatitis, biliary obstruction, hepatic encephalopathy, chronic active hepatitis.

The toxin can cause severe damage to your dog's gastrointestinal tract which can lead to prolonged healing, loss of appetite, inability to absorb nutrients from his food, or even necrosis of a part of the digestive system.

Veterinarians say that puppy's heart when being infected by the CPV develops necrosis and thus the heart in the end stops beating.

«The rate of tumor necrosis due to 3BP treatment seems to exceed all known cytostatic drugs,» they wrote.

Catalase abrogates ß - lapachone - induced PARP1 hyperactivation - directed programmed necrosis in NQO1 - positive breast cancers.

«When people look at necrosis,... they kind of never think that this can be controlled.»

Across multiple triple - negative breast cancer subtypes, inhibiting the androgen receptor greatly increased apoptosis (programmed cell death), inhibited growth and increased necrosis by 60 percent in animal models.

Molecular Diagnostics - The Molecular Diagnostics section offers routine PCRs for Salmonella and Leptospira bacterial species, and viral agents including chicken proventricular necrosis virus (CPNV, TVP) and avian infectious laryngotracheitis (ILT).

First Follow - up Radiographic Response is One of the Predictors of Local Tumor Progression and Radiation Necrosis After Stereotactic Radiosurgery for Brain Metastases.

They include: Lacerations, skin bridges, chordee, meatitis, meatal stenosis, urinary retention, glans necrosis, hemorrhage, meningitis, sepsis, gangrene, and penile loss requiring sex re-assignment.

Factors such as the degree of shock, severity of the condition, cardiac problems, stomach wall necrosis (damage) and length of surgery can affect survival rate.

The characteristic gross lesions at necropsy consist of disseminated focal necrosis and hemorrhages.

Still, it's not clear yet how well necrosis can be controlled, he cautions, and the jury's still out on whether Silverman's work will translate to humans.

Olive Leaf Extract lowers the concentration of triglycerides in the fattened rats, inhibits the growth of the left ventricle in the heart and protects the liver against necrosis.

Veterinary surgeons have found that the virus results in microscopic necrosis of heart tissue in dogs that do not survive.

If necrosis or perforation develops, euthanasia should be seriously considered.