The science behind this has been little understood until now, and possible
effects on human cells were not previously investigated.
When isolated and
tested on human cells, these compounds were found to reduce testosterone levels and increase estrogen levels.
As another example, the structures of sugars on disease - causing bacteria look vastly different from the
sugars on human cells.
Previous molecules created to
act on human cells were shown to cause harmful side effects.
These projects explore the consequences of genome
variation on human cell biology, and thus gene function in health and disease.
According to them this technique is adaptable to any species and its use could be
made on human cells.
Researchers have long sought to understand how it is that using a chemical designed to specifically target bacteria could actually bring about such damaging
effects on human cells.
The extract was
tested on human cells, and the generation of reactive oxygen species (free radicals) by immune system actors was significantly suppressed.
In earlier
work on human cells led by Dr. Fish, researchers compared how well eight different drugs, in different combinations, at different doses, were able to inhibit the Ebola virus.
She helped lead a GSK project focused on designing a monoclonal antibody to link to the HER3
receptor on human cells as a treatment for cancer.
Prins investigated the effect of BPA
on human cells by implanting human prostate stem cells taken from deceased young - adult men into mice.
The device has made it possible for researchers to study bacteria and viruses in the field, but its high error - rate and large sequencing gaps have, until now, limited its
use on human cells with their billions of nucleotides.
Our investigations
on human cell lines in the laboratory have shown that synthetic cannabinoids, in the high concentrations found in cells in the oral cavity or in the lungs, for example, are likely to trigger damage to the DNA that may have significant consequences for the consumers of such substances.
The new flu, known as H7N9 avian influenza, latches onto sugars that coat bird cells — and it can cling to sugars
on human cells too, Yuelong Shu of the China Center for Disease Control and Prevention and colleagues...
Dr. Sadelain's research
focuses on human cell engineering and cell therapy to treat cancer and hereditary blood disorders.
«We started working
on human cells more than a year ago, but in the beginning, the four factors didn't work,» he told NPR.
Researchers at the University of North Carolina School of Medicine in Chapel Hill tested the effects of 148
e-liquids on human cells.
With proper repetitions, negative controls and statistical analyses, the effects of carrageenan
exposure on human cells can be better understood.
Much of Hwang's work
on human cells turned out to be fraudulent, but Snuppy was not, an investigation later concluded.
University of Connecticut chemists developed a way to detect how much damage e-cigarettes may
inflict on human cells.
After syphilis establishes this symbiotic relationship with a person, it becomes
dependent on human cells and is undetectable by any testing.
Tests on mice and
on human cells showed that the sponge could arrest cancer, but scientists did not have a large enough sample to do further research.
Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same
brew on human cells, the number altered was modest.
The Fraunhofer IGB develops alternatives
based on human cells to verify the biocompatibility of substances.
They and others aiming to set guidelines for the myriad uses of CRISPR and its
brethren on human cells clearly have no easy task.
Conventional technology such as mass spectrometry and nuclear magnetic resonance can measure such components — that is how biochemists test the toxicity of drugs or environmental
pollutants on human cells.
The Discher Lab has since shown that a protein
on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.
The team of researchers conducted the experiments — which had previously been performed on rodent cells — also
on human cells which they cultured in the laboratory.
«Sessano and colleagues have developed a useful tool for screening large numbers of e-liquids for toxicity using laboratory
experiments on human cells.
Thus far (2016), there is no organism it doesn't work on (CRISPR has been used
successfully on human cells, but not yet in viable human embryos).
For three years now we have been working
on human cell models of rare neurodegenerative diseases with special emphasis on neuroacanthocytosis, neuronal ceroid lipofuscinosis as well as motor neuron degeneration (using iPS cells).
In the study, tests
on human cells demonstrated that catuaba may help fight Parkinson's disease by protecting against the degeneration of certain nerve cells.
In a study published in the Journal of Cellular Biochemistry the same year, tests
on human cells determined that Cissus quadrangularis may help stimulate the growth of bone - forming cells known as osteoblasts.