Sentences with phrase «therapeutic development»
These recently published findings may offer scientists a new target for therapeutic development in HD.
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That nanoparticles can be coupled to different antibodies and retain efficacy suggests flexibility for future applications, including human therapeutic development.
A major factor for this may lie in the increased complexity of the companion diagnostic and corresponding therapeutic development and adoption pathways.
«It will [also] have important connections to future therapeutic development for other severe disorders of consciousness,» said company founder Dr. Sergei Paylian.
Dr. Scheller is Chief Scientific Officer and head of therapeutic development at 23andMe.
«These results are particularly exciting because they suggest that drugs directed at fusion - circular RNAs could be a powerful strategy to pursue for future therapeutic development in cancer,» said Pandolfi.
Supports work that can accelerate neurotrophic factor therapeutic development for Parkinson's disease (PD).
The next phase of the Microbiome Initiative will apply a translational approach to established concepts to yield a productive pipeline of microbial targets and initial lead molecules suitable for entry into preclinical therapeutic development.
«Our MAP technology has been effective as part of many therapeutic development programs and for identifying biomarker patterns linked to complex diseases.
«Biomarkers are critical to accelerating therapeutic development for any disease.
«We are thrilled about the potential this collaboration holds to accelerate ALS therapeutic development,» said Steve Perrin, PhD, CEO and Chief Scientific Officer at ALS TDI.
This fall, several landmark federal research meetings are being conducted to address critical regulatory and therapeutic development opportunities in SMA.
«This is the first study done that identifies a target, JNK3, that's independent of the genetic mutation of spinal muscular atrophy for novel therapeutic development.»
While increasing efforts are geared toward therapeutic development, an effective drug for ALS has yet to be identified, in large part because of our incomplete understanding of the disease.
«The whole signaling thing, people are very excited about that,» Hajduk said, «whether it's infectious disease or cancer or specific therapeutic development» to treat sleeping sickness.
Affigen's team houses deep expertise in immuno - oncology, mass - personalized biomolecular engineering and complex therapeutic development.
«We believe that this will facilitate translation of existing innovative projects at Swedish universities towards therapeutic development», says Karin Forsberg Nilsson, Scientific Director at SciLifeLab, and Acting Director for the Uppsala site of the DDD platform.
«By combining Merck's strength in vaccine and antiviral therapeutic development with Moderna's mRNA Therapeutics technology we are well positioned to develop differentiated candidates with the potential to provide meaningful benefit to patients,» said Dr. Roger M. Perlmutter, president of Merck Research Laboratories.
In collaboration with DARPA, Moderna introduces its first infectious disease therapeutic development candidate, mRNA - 1944, encoding an antibody against Chikungunya virus
«This collaboration has already resulted in exciting new capabilities and insights for R&D for small airway diseases, and we look forward to further advancing the application of the Organ - Chips to improve therapeutic development».
Our first liver therapeutic development program is for methylmalonic acidemia (MMA), a serious and often life - threatening rare liver disease; it is primarily a pediatric disease with onset in early infancy.
The results provide a better understanding of SMA pathogenesis and inform on SMA therapeutic development strategies.
The results are «important both for mechanistic study and also for potentially therapeutic developments,» said Yadong Huang of the University of California, San Francisco, and the Gladstone Institute of Neurological Disease, who also was not involved in the work.
We are concerned that a public outcry about such an ethical breach could hinder a promising area of therapeutic development,» write Lanphier and his colleagues, who include Fyodor Urnov, a pioneer in gene - editing techniques and scientist at Sangamo BioSciences in Richmond, California.
Investigators advance their discoveries through small - molecule - based drug discovery, an area where we have significant capabilities, into early preclinical therapeutic development.
ALS TDI collaborates with leaders in both academia and industry to accelerate ALS therapeutic development, including Biogen Idec, UCB, Aestus Therapeutics, MDA and RGK Foundation.
«These compounds will shortly enter the clinic for therapeutic development in cancer, and we expect they can also be immediately developed into therapies for heart failure.»
For decades, the Tourette Association of America has led the way in research and therapeutic development for Tourette Syndrome and other Tic Disorders, and has provided more than $ 20 million in grants to fund research and develop medical programs that meet the needs of those affected by Tourette.
The teams at MD Anderson's and Center for Co-Clinical Trials are using the PILOT platform to investigate novel vulnerabilities across tumor subtypes with the aim of identifying targets for therapeutic development.
With companies able to protect their patents in the United States and elsewhere, and competitors unable to easily create generic and knock - off embryonic - stem - cell treatments, the impact of the European ruling on investment and therapeutic development should be blunted, says Denoon.
«Using approved therapies for one condition to treat another, or drug repurposing, offers new avenues to speed Parkinson's therapeutic development,» said Dr Brian Fiske, senior vice president of research programs at MJFF.
As the peptide is protease - resistant, its therapeutic development feasible, as nobody wants to take a medicine every 5 minutes; furthermore, this peptide could be produced on a large scale.
«Cause of heart arrhythmia in adult muscular dystrophy clarified: Key findings for the prevention of death and the therapeutic development.»
«Two classes of GGAA - microsatellites in a Ewing sarcoma context: Characterization of GGAA - microsatellites provides insight in the role of noncoding DNA in cancer susceptibility and therapeutic development.»
This is important to therapeutic development, Sherwood said, as the neural mechanisms of tinnitus are unknown but likely related to attention.
But NCATS «is not going to become the place where all the therapeutic development at NIH goes on,» Collins said.
«The dBET1 and the dFKBP12 compounds are presently in a late stage of lead optimization for therapeutic development in both cancer and non-malignant diseases,» says Prem Das, PhD, chief research business development officer at Dana - Farber.
Caribou's tools and technologies provide transformative capabilities to basic and applied biological research, therapeutic development, agricultural biotechnology, and industrial biotechnology.
AMP T2D focuses on type 2 diabetes genetics, seeking to use and supplement the substantial amount of human genetic data available from people with type 2 diabetes, or at risk of developing it, to identify and validate novel molecules and pathways as targets for therapeutic development.
Researchers have been developing oncolytic viruses since the 1980s, but following the U.S. Food and Drug Administration's 2015 approval of Amgen's Imlygic (T - Vec) as the first oncolytic viral therapy in the U.S., such viruses have become a closely watched area of therapeutic development.
With the reference cell census data in hand, the research team is excited to conduct additional studies, including ones involving models or human patients with gastrointestinal conditions — Crohn's disease, ulcerative colitis, gastrointestinal cancers, forms of food allergy, etc. — aimed at identifying changes in gene expression and epithelial structure and function that could reveal new insights and opportunities for therapeutic development.
Objective: To provide data - driven and computational infrastructures and data - sharing platforms to support large - scale, system - level data integration and modeling, and enable predictive biology for pathogens and host - pathogen interactions for discovery research, clinical investigation, and therapeutic development for infectious diseases.