Sentences with phrase «blood stem»

With this procedure, adult stem cells, which are also called peripheral blood stem cells, are taken directly from drawn blood.

The other two sources are bone marrow and peripheral blood stem cells.

They are particularly responsible for the self - renewal of blood stem cells.

Still, scientists are hopeful that someday adult patients will routinely be able to receive cell therapies based on cord blood stem cells.

Finally, the researchers cultured them into blood stem cells of the type that could potentially be injected into patients to reverse their disease.

Normally, the bone marrow makes blood stem cells that develop into mature blood cells over time.

Scientists have taken a major step forward to making artificial blood by creating blood stem cells in the lab.

He says the structure could also offer a new way of studying blood stem cells and how blood disorders arise.

The sixth patient included in the report received a booster dose of gene - corrected blood stem cells.

Both groups isolated carefully characterized blood stem cells from genetically marked mice.

They proved that the absolute oxygen concentration around blood stem cells was indeed low, despite a very large density of the blood vessels.

DNA mutations in bone cells that support blood development can drive leukemia formation in nearby blood stem cells.

Because of the political controversies over embryonic stem cells, information about cord blood stem cells had been unclear.

The new treatment removes more than 98 % of blood stem cells, making it as effective as chemotherapy and radiation.

This method would also enable them to follow potential aging processes that occur in blood stem cells in detail as they occur naturally in a living organism.

To further investigate this hypothesis, the team transplanted fetal mice with blood stem cells from a second strain of mice that were not matched to the fetus or the mother.

«Protein that keeps blood stem cells healthy as they age identified by researchers.»

A team of researchers at the University of Queensland has developed a new process that has successfully silenced a severe allergic response in mice, using blood stem cells engineered with a gene that can target specific immune cells.

Mayack and Wagers are the sole authors on the Blood paper, which examines the role of bone cells in regulating blood stem cells.

Essentially, the aim is to genetically alter patients» own blood stem cells so they don't produce abnormal hemoglobin.

Scientists from the German Cancer Research Center (DKFZ) have developed a way to equip mouse blood stem cells with a fluorescent marker that can be switched on from the outside.

Right now, the only cure for some CSAs is a stem cell transplant — the transplantation of normal blood stem cells from another person («donor») to your child.

His current work deploys post-genomic technologies and mathematical modeling approaches to gain further insight into how blood stem cells are configured in molecular terms, the nature of the pathways involved in their cell fate decisions, and how these are corrupted by chimaeric transcription factors associated with human leukaemia.

A research group at Lund University in Sweden has been able to show that bile acid is transferred from the mother to the fetus via the placenta to enable the fetus to produce blood stem cells.

The retracted paper, which was cited 13 times, according to theWeb of Scienceonline citation index, describes a series of experiments - including stitching together the circulatory systems of old and young mice - to show that age - related changes in adult blood stem cells can be influenced and even reversed by their environment.

In both cases, the mechanisms are similar: the «good» mechanism regulates healthy blood stem cells during an infection, whilst the «bad» one leads to the multiplication of leukemia stem cells.

«We take blood stem cells, insert a gene which regulates the allergen protein and we put that into the recipient,» says Professor Ray Steptoe, explaining the new process developed by his team at The University of Queensland.

Blood Cells Turned into Beating Heart Cells In a collaboration between the Kimmel Cancer Center, Institute for Cell Engineering, and Department of Biomedical Engineering, researchers successfully turned blood stem cells into functional, beating heart cells.

This fits with studies we've conducted in the past in which we found that the gene primes blood stem cells for leukaemic transformation.»

«When we transplanted our labeled blood stem cells from the bone marrow into other mice, only a few stem cells were active in the recipients, and many stem cells were lost,» Rodewald explains.

Several Japanese medical experts want to bank blood stem cells from workers at the ailing Fukushima Daiichi nuclear plant.

Pregnant mother protect growing blood stem cells in the liver of fetus by transporting bile acid.

(The cells would be obtained by giving the workers a drug that nudges blood stem cells from the bone marrow into the bloodstream, then hooking them to a machine that filters out the stem cells.)

Researchers at the University of Birmingham have made a breakthrough in understanding how mutated genes in leukemia reprogram blood stem cells and send them spiralling out of control.

«These splicing signatures could potentially be used as clinical biomarkers to detect blood stem cells that show signs of early aging or leukemia, and to monitor patient responses to treatment,» said Crews.

MDS affects blood stem cells, preventing them from becoming mature, healthy blood cells.

If blood stem cells aren't the next big thing, another cell, discovered by researchers at the University of Minnesota's Stem Cell Institute in Minneapolis, might be.

In order to learn more about this process, Alexander Skupin and his team treated blood stem cells from mice with growth hormones and then watched closely how these progenitor cells behaved during their differentiation into white or red blood cells.

This study has shown that young blood stem cells that lack SIRT1 behave like old ones.

The investigators also plan to look at whether SIRT1 therapy could treat diseases already linked to aging, faulty blood stem cells.

To explore the potential for application, the group then attempted a similar experiment using human blood stem cells taken from umbilical cords, which they transfected with a vector encoding human Id3.

Reporting online this week in the journal Nature, Juan Carlos Belmonte of the Salk Institute in San Diego and colleagues in Spain say they have successfully generated genetically tailored iPS - derived blood stem cells that could potentially treat patients with Fanconi anemia.

The treatment involves collected blood stem cells carrying the genetic anomaly of patients and corrected them in the laboratory by introducing a healthy WAS gene using a lentiviral vector developed and produced by Genethon.

In the second study, a team led by Shahin Rafii at Weill Cornell Medicine in New York City used adult mouse cells as their starting material, and then guided them through several steps — including exposure to some of the same gene - activating proteins — to create mature blood stem cells in a petri dish.

Protein cocktail They found that five of these so - called transcription factors, working together, yielded the elusive blood stem cells — the starter kit for white and red blood cells, platelets, macrophages and all the other cell types of which blood is composed.

In one of her major contributions, Torok - Storb demonstrated the importance of the interactions between blood stem cells and the supportive cells in the marrow.

Through a monumental effort, Camargo developed a genetic barcoding system to mark individual blood stem cells and their progeny in living mice, sidestepping transplantation and radiation.

Toronto scientists James Till and Ernest McCulloch didn't discover blood stem cells until 1960.

A switch has been discovered that instructs blood vessel cells to become blood stem cells during embryonic development in mice.