Sentences with phrase «cell genomics»

The researchers used single cell genomic sequencing, a very useful and still comparatively new capability.

Single ‐ cell genomic techniques have advanced our understanding of several developmental processes.

Single cell genomics allows the separation and isolation of cells to extract and sequence individual parasite DNA and determine any differences between the parasites within an infection.

The combination of these methods enables complex tissues to be studied by single cell genomics workflows, revealing interrelationships between molecular and cellular phenotypes within tumor microenvironments.

The Microbial Single Cell Genomics facility in Uppsala is already operational and aims to provide a broad range of single cell genomics services.

This is our dream for personalized cancer therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem cell genomics at the UCSC Genomics Institute, and a senior corresponding author of the paper.

The experimental plan includes a fine - grained analysis of the different cell populations within these precious tissues using cutting - edge single - cell genomics methods.

Alexander J, Kendall J, McIndoo J, Rodgers L, Aboukhalil R, Levy D, Stepansky A, Sun G, Chobardjiev L, Riggs M, Cox H, Hakker I, Nowak DG, Laze J, Llukani E, Srivastava A, Gruschow S, Yadav SS, Robinson B, Atwal G, Trotman L, Lepor H, Hicks J, Wigler M, Krasnitz A. Utility of single - cell genomics in diagnostic evaluation of prostate cancer.

In a recent proof - of - concept experiment, Abate and his colleagues performed single - cell genomic sequencing on a sample of seawater.

They elaborate on several focus areas described by the White House earlier: preventive vaccines, early detection, single cancer cell genomics, immunotherapy, pediatric cancer, and data sharing.

Recent advances in single - cell genomics technology has made it possible to separate individual cells from different tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each cell its own identity.

Genome of the pathogen Porphyromonas gingivalis recovered from a biofilm in a hospital sink using a high - throughput single - cell genomics platform.

Promoting SINgle cell GEnomics to explore the ecology and evolution of hidden microeuKaryotes

Published in Nature, the single - cell genomics study was led by the European Bioinformatics Institute (EMBL - EBI) and the University of Cambridge.

Using the oral microbial community as a model system, we are applying functional genomic approaches including Stable Isotope Probing (SIP), metatrascriptomics and directed single cell genomic approaches to enable us to overcome this limitation.

Recognizing the remarkable opportunities to apply single cell technologies to major questions in biology and medicine, JAX recently launched a joint center for single cell genomics together with the University of Connecticut, including UConn Health.

Connection to SciLifeLab: Director at the Single cell genomics facility.

Single cell genomics means that one can study the genetic material of single cells.

Robert Aboukhalil use his skills as a computational biologist to make single - cell genomic data easy for scientists and clinicians to access and use...

Our single cell genomics toolkits allow us to deconvolute sample and tissue heterogeneity and to track dynamic changes throughout stimulation or perturbation.

SingulOmics and Novogene now work together to offer a complete single - cell genomics workflow as a service.

Like SingulOmics and Novogene, BGI offers a range of single - cell genomics services.

The use of single - cell genomics allows sequencing of individual parasites directly from a patient's blood.

Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates — Jürgen F H Strassert, ISME

Recent developments in the field of metagenomics and single - cell genomics, however, have allowed the reconstruction of archaeal genomes directly from environmental samples without prior cultivation.

Single - cell genomics could provide new insight into the biology of Malaria parasites, including their virulence and levels of drug resistance, to ultimately improve treatment and control of the disease, according to new research funded by the Wellcome Trust and the National Institutes of Health.

«A common problem in the field of single cell genomics is the inability to validate mutations that are detected in individual cells,» said Yong Wang, Ph.D., a postdoctoral fellow in the Department of Genetics and first author on the study.

«It's the same process as for single cell genomics, but for aggregates of symbiotic bacteria and archaea,» said DOE JGI Microscale Applications Group head Rex Malmstrom of the technique called BONCAT - FACS (BONCAT — Fluorescence - Activated Cell Sorting).

The team, which also includes Raul Rabadan, PhD, professor of systems biology and biomedical informatics at CUMC, will use single - cell genomics to create a unique, genetic ID tag for each cell in the spinal cord.

In the recent years, culture - independent methods, such as metagenomics and single cell genomics have been developed that allow for the genomic exploration of this so - called «microbial dark matter».

«Over the last several years, single - cell genomics has become a popular tool to complement metagenomics,» said study senior author Tanja Woyke, head of the DOE JGI Microbial Program.

«There are many efforts around the world to systematically determine the transcript levels in cells, tissues and organs, involving new technologies such as single cell genomics and spatial transcriptomics».

«Single cell genomics can be applied to understand the heterogeneity of tumors, to explain how genetically identical cells may show distinct behavior, and to explore the vast, uncharacterized microbial landscape.

Currently, we are exploring several environmental samples retrieved from allover the world - ranging from hydrothermal vents in Japan to hot springs in Yellowstone National Park and New Zealand — for the presence of novel archaeal (and bacterial) lineages using cultivation - independent approaches, such as metagenomics and single cell genomics.

Single cell genomics is an emerging technology enabling the exploration of genomes of individual microbial cells without the need for prior cultivation.

To do so, she will use novel cultivations - independent techniques such as metagenomics and single - cell genomics, but also more

Courtney did her PhD at Dalhousie University (Halifax, Canada) and recently joined Ettema - lab to investigate the diverse protist biology using single - cell genomics and transcriptomics.

High - throughput single - cell genomics has transformed our understanding of complex cell populations.

Scientific programs include: human genomic sequencing and analysis, synthetic genomics and exploration of new vaccines using this technology, and environmental and single cell genomics to explore the vast unseen world of microbes living in the human body, the ocean, soil and air.

My lab is dedicated to explore the vast uncharacterized microbial diversity using cutting - edge culture independent technologies, such as single cell genomics and metagenomics.

Single cell genomics allow us to take a drop of water from any pond around the globe, separate the microorganisms it contains and classify them individually according to their genetic information.

His lab develops novel single cell genomic and epigenomic methods to characterize the immune system and develop new targets for immunotherapy.

With single cell genomics, we have a tool that gives us this information from each individual, with all their diversity included.