Sentences with phrase «genomic sequence»
The phrase "genomic sequence" refers to the complete set of instructions or code that defines an organism's characteristics. It is like a blueprint that contains the specific order of DNA molecules within an organism's genome. By analyzing this sequence, scientists can understand the genetic makeup of an organism, such as which genes it has and how they function. Full definition
Currently, the risks and benefits of genomic sequencing for newborns are not well understood.
genomes2people.org
Despite the promise of genomic sequencing for personalized medicine, there remain significant challenges and concerns that must be addressed.
To determine the genetic profile of a patient's tumor and identify cancer - driving genes, our team of experts uses advanced genomic sequencing technology.
The researchers used single cell genomic sequencing, a very useful and still comparatively new capability.
Consider genomic sequencing, which has been touted as the essential tool needed to move medicine from standardized and reactive to personalized and preventive.
It urged clinicians to tell people undergoing genomic sequencing whether their genes might make them more likely to develop serious disease in the future, even if they didn't want that information.
Single - copy genomic sequences were amplified by a factor of more than 10 million with very high specificity, and DNA segments up to 2000 base pairs were readily amplified.
Understand new and established genomic sequencing technologies, and how to apply them in clinical practice.
Are you ready to try a new high - quality eLearning tool that enables you to explore ethical and social questions surrounding genomic sequencing?
Another reason to consider personal genomic sequencing is if a disease with a potential genetic component is present in other family members.
This method is designed to discover gene function and validate candidate genomic sequences involved in human disease.
To address that need, Sidhom used high - powered computing to create a mathematical model — essentially a digital map — of genomic sequence data of receptors from human T - cells that were exposed to a virus in the laboratory.
Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals Hellmann, I., Y. Mang, Z. Gu, P. Li et al. 2008.
Advances in genomic sequencing technologies have improved the ability to detect molecular aberrations with greater sensitivity and to identify genomic alterations that can be matched to targeted therapies.
With genomic sequencing detecting ERBB2 alterations in this form of cancer, we have an opportunity to identify anti-cancer therapies that would specifically target that abnormality and that would otherwise not be given to those patients who could benefit.
For the study, which was published in Nature Communications, the group performed whole genomic sequencing on 30 individual tumors classified as liver cancer displaying a biliary phenotype.
Elodie Ghedin, a biomedical researcher at the University of Pittsburgh in Pennsylvania, who uses genomic sequencing techniques to generate insights into human pathogens.
Notably, the closest identified phylogenetic relative to TMAdV among the complete genomic sequences available in GenBank is a rhesus monkey adenovirus, SAdV - 3 (Fig. 4; Table 2).
This application uses calculated break points to determine fusion genes based on the latest annotation for genomic sequence information, and where relevant the structural variation (SV) events are annotated with predicted RNA and protein sequences.
As genomic sequencing methods continue to identify large numbers of novel cancer mutations, how can we identify the mutations in a given tumor that are most critical to the maintenance of its oncogenic phenotype?
Background: Nanopore sequencing is a third generation genomic sequencing method that offers real time sequencing of DNA samples.
Using whole genomic sequencing, scientists from RIKEN in Japan have for the first time demonstrated the profound effect that chronic hepatitis infection and inflammation can have on the genetic mutations found in tumors of the liver, potentially paving the way to a better understanding of the mechanisms through which these chronic infections can lead to cancer.
The PeopleSeq Consortium enables us to collect valuable empirical data on the medical, behavioral and economic impact of performing genomic sequencing in healthy adults.
In yeast and Caenorhabditis elegans, the majority of ORFs revealed by genomic sequencing have not been associated with mutant phenotypes, even in genomic regions that have been subjected to saturation mutagenesis (36 - 37).
Topics at «Genetics — Moving to the Center of Healthcare» include the role of genomic testing in guiding cancer treatment, approaches to helping families that are coping with genetic diagnoses, and interpretation and use of genomic sequencing results in the newborn population.
Bioinformatics is fed by high - throughput data - generating experiments, including genomic sequence determinations and measurements of gene expression patterns.
The LMM and the Broad CRSP lab offer genomic sequencing services for both clinical diagnostics and to support several genomic medicine research projects including the MedSeq and BabySeq projects and the eMERGE program.
The use of this metadata standard by all ongoing and future GSCID sequencing projects will provide a consistent representation of these data in the BRC resources and other repositories that leverage these data, allowing investigators to identify relevant genomic sequences and perform comparative genomics analyses that are both statistically meaningful and biologically relevant.
To assess geographical diversity in marine viral communities, Sullivan and his team looked at double - stranded DNA viral genomic sequence data, or viromes, and whole viral community morphological data across 43 Tara Oceans expedition samples.
Population genetic inference from genomic sequence variation Pool, J. E., I. Hellmann, J. D. Jensen, and R. Nielsen.
Center will utilize next generation genomic sequencing and analysis technologies to better understand infectious disease pathogens, and create resource for the research community
According to Knut Bauer of the research ministry, a planned policy granting industrial contributors 3 months of exclusive access to human genomic sequence data before they are put on the Internet may soon be dropped in favor of immediate release.
This suggests biological systems encode limited precision and efficiency, and that phenotypes are not independent of each other, but co ‐ determined by the same genomic sequences.
The research is described in «Nuclear Genomic Sequences Reveal that Polar Bears Are an Old and Distinct Bear Lineage,» a paper being published on Friday in the journal Science.
We offer genomic sequencing for patients who have metastatic disease, have failed treatment and have good performance status (spend 50 percent or more of the day mobile and out of bed).
Helix performs a type of Genomic Sequencing called «exome - plus» (Exome +) sequencing, which involves sequencing the part that codes for the proteins that tell your body how to function, or the «exome.»
The 3000 Rice Genomes Project, a collaboration between the Chinese Academy of Agricultural Sciences, the International Rice Research Institute, and BGI, provides a massive rice genomic sequence resource for worldwide use.
The 3000 Rice Genomes Project, a collaboration between the Chinese Academy of Agricultural Sciences, the International Rice Research Institute, and BGI, provides a massive rice genomic sequence resource for worldwide use.
In a study that included children and young adults with relapsed or refractory cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMA.
They mapped the spread from patient to patient, and facility to facility, based on both the sleuthwork Hayden's team had done and the new genomic sequence information.
In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high - intensity genomic sequencing approach detected circulating tumor DNA at a high rate.
«If you did genomic sequencing, all of these particular genes would be normal,» Longmore says.
In the article describing the work in Molecular Therapy, co-authors Charis Himeda, Takako Jones and Peter Jones highlight the important implications for similar types of genetic diseases: «With increasing evidence that the repeat genome (comprising nearly half the human genome) plays important roles in gene regulation, additional diseases will likely be found associated with aberrant repetitive genomic sequences,» they write.
«Revolutionizing genomic sequencing of drug - resistant bacteria.»