Sentences with phrase «new tumors»

This could help eliminate the residual cancer cells that often form new tumors following surgery.

And while the altered protein also contributed to the growth of already - present tumors, it did not trigger the spontaneous development of new tumors.

They find that the cells can remain dormant during chemotherapy that kills off most of the cancer and can give rise to new tumors once the drug treatment stops.

Others may experience new tumors, located in the bladder or in other areas of the body.

But they give no explanation as to how they came to the convenient conclusion that no really new tumors were formed.

So a little extra, careful attention might be needed, especially if new tumors tend to pop up occasionally.

This allowed them to map a «family tree» of the changes happening at a genetic level as the disease spreads, forms new tumors, and becomes resistant to treatment.

The aggressive basal - type breast cancers often metastasize, seeding new tumors in distant parts of the body.

Whitehead Institute researchers have determined that in basal breast cancer cells a transcription factor known as ZEB1 is held in a poised state, ready to increase the cells» aggressiveness and enable them to transform into cancer stem cells capable of seeding new tumors throughout the body.

In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer stem cells in mice and in lab cultures, and it also prevented the growth of new tumor cells.

Metastasis is the process in which cells from a primary tumor break - off, enter the blood stream and create new tumors elsewhere in the body.

In 80 to 90 percent of the mice, tumors disappeared completely; even when tumor cells were reinjected into the mice months after the original treatment, their immune systems destroyed the cells, preventing new tumors from forming.

This allows cancer cells to break off from tumors, spread throughout the body (in blood or other fluid) and form new tumors at distant sites — a process called metastasis.

Cancer cells depend on a number of oncogenes, like EphA2, to form metastasis, the medical term for cancer spreading from the primary site to other regions in the body, accomplished when cancer cells break away from the primary site, travel through the blood or lymph system, and form new tumors elsewhere in the body.

«Circulating tumor cells (CTCs) have been shed by the original tumor and entered the bloodstream — they can then form into new tumors if they lodge in distant tissue,» Wang says.

When the researchers injected these tumor cells into the tail veins of 35 mice, nearly twice as many new tumors sprouted in the lungs of cyclosporine - treated mice compared to control animals.

Once these cells have spread to other organs, the cancer has metastasized, and the cells have the ability to initiate new tumors throughout the body.

Previous work in the Weinberg lab showed that adult cancer cells passing through an EMT are able to self - renew and to seed new tumors with high efficiency, hallmark traits of CSCs.

«Our preclinical study indicates that SapC - DOPS does both and inhibits the growth of new tumor blood vessels, suggesting that this agent could one day be an important treatment for glioblastoma and other solid tumors.»

And how do occasional cells survive in this vulnerable state — sometimes hiding out in the brain for years — to eventually spawn new tumors?

Some scientists have blamed so - called cancer stem cells, a subset of cancer cells that might be able to remain dormant, evading chemotherapy or radiation treatments, only to form new tumors months or years later.

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

Studies have shown that stress might promote cancer indirectly by weakening the immune system's anti-tumor defense or by encouraging new tumor - feeding blood vessels to form.

On the safety side, the panelists delved into the possible risks of injecting genetically modified cells into patients, including the potential for deadly viral infections, brain toxicity, and, paradoxically, the growth of new tumors brought about by CAR - T cells years after treatment.

Singlet oxygen tends to rip apart tumor cells in a manner that exposes many new tumor antigens to immune cells called dendritic cells, which, like police executing a dragnet, grab the antigens and present them to T cells for closer inspection.

A small population of cells, known as glioblastoma stem cells, often survives the onslaught and continues to divide, producing new tumor cells to replace the ones killed by the cancer drugs.

«This combination of features means that the drugs can not only attack the main tumor site, but are more likely to find and attach themselves to tumor cells circulating in the bloodstream — essentially attacking new tumors before they start,» says Quanyin Hu, lead author of the paper and a Ph.D. student in the joint biomedical engineering program.

Rose is currently awaiting results from a new round of mice in development using newer tumor cells.

The CSC theory suggests that such CSCs persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors [8 — 10].

Surprisingly, survival benefits were best in men whose new tumors were growing fastest, according to results of a «look - back» study of 635 men by Johns Hopkins Medical Institutions researchers reported June 18 in the Journal of the American Medical Association.

At the same time, new tumor entities have been identified that can not be defined histologically.

If they are not completely destroyed they are capable of continuous differentiation, they able to self renew and create new tumor colonies.

In the laboratory animal study, ursolic acid, the active compound in holy basil, combined with radiation was more effective at inducing skin cancer cell death and inhibiting new tumors from forming than radiation alone.

When new tumors showed up in Clea's lungs, he referred Clea to an American trained board certified small animal internal medicine specialist at his clinic, Dr. Suzy Valentin.

Published in the February 27 issue of Cell, the study found that tumor cells that reach the brain — and successfully grow into new tumors — hug capillaries and express specific proteins that overcome the brain's natural defense against metastatic invasion.

Malignant adrenal cancers may spread through the body by invading the adjacent blood vessels and seeding new tumors in body cavities and other organs.

The initial experiments made use of cancer cells that Quiñones - Hinojosa and his team removed from willing patients and grew in the laboratory until they formed little spheres of cells, termed oncospheres, likely to be the most resistant to chemotherapy and radiation, and capable of creating new tumors.

Metastatic disease refers to cancer that has spread through the blood or lymph system to form new tumors in other parts of the body distinct from the original site.

Next steps for this research will see new refinements in the endomicroscope instrument and development of new tumor cell stains and probes that light up the tumor cells to an even greater degree.

Other investigators believe that lymph node metastasis is an essential part of the process leading to metastases in other parts of the body and that metastatic cells in the lymph nodes pass into the bloodstream and seed the growth of new tumors.

It is well established that melanoma cells can spread through the blood to accumulate and form new tumors (metastases) in other parts of the body away from the original tumor.

So even if a tumor is surgically removed, it is difficult to extract every cancerous cell; any left behind will result in the growth of a new tumor.

Four days before Lent, I hold a tried and true friend's hand and she takes off her wig and looks me straight in the eye when she tells me that this new tumor's inoperable and this will be her Cancer 2.0.

Though this approach kills the majority of tumor cells, it often spares a small number of tumor - initiating cells (TICs) that subsequently give rise to new tumors.

In a tumor, the faster growing cells «piggy - back» along with the more invasive cells, so together they can be more effective in establishing a new tumor once they have reached different parts of the body.

Researchers have previously thought that single rogue cancer cells broke away from tumors and migrated to other places in the body where they could later give rise to new tumors.

Comparing the metastasized tumors with the original breast tumors, the researchers were surprised to learn that multiple, slightly genetically different cells from the original site had broken away together and established the new tumors.