Sentences with phrase «cell surface proteins»

The Major Histocompatibility Complex (MHC) is a region of the genome that contains genes that code for a group of cell surface proteins known as Dog leukocyte antigens (DLA).

These immune cell surface proteins in themselves help the body by making our DNA less vulnerable to attack by our immune system which may have gone on the attack of foreign particles in our blood, such as dead cells, parasites, viruses, pollens and more.

They study how specific cell surface proteins regulate nervous system development, including formation of myelin, the insulating layer around neurons that degenerates in MS. Myelin ensures rapid flow of electrical signals, similar to the plastic coating around a wire and protects neurons from degenerating.

They identified these cells by looking for cell surface proteins called CD31 and CD146.

«That is why detecting early esophageal cancer with fluorescent probes to highly expressed cell surface proteins are necessary.»

The Major Histocompatibility Complex (MHC) is a region of the genome in dogs that contains genes that encode a group of cell surface proteins known as Dog leukocyte antigens (DLA).

The system could be used for analyzing low expression cell surface proteins and for high - throughput screening for industrial enzyme production.

In this study, the SIgN team discovered for the first time that the integrity of p53 affects the production of a special cell surface protein called Major Histocompatibility Complex (MHC) class I. MHC class I molecules on the cancer cell surface serve as targets for the immune system.

CD14 A cell surface protein abundant in human milk, is present when the immune system learns to fight pathogens in the intestines.

The flawed data did not contradict the paper's main claim that the injected cells have a potential similar to that of embryonic stem cells, researchers say, because they could simply have had other cell surface proteins not included in the data.

Coupled with the fact that replicating and non-replicating bacteria have different cell surface proteins, the initial experiments suggest that a biomarker, easily assayed in blood samples, could be developed based on the appearance of CD4 + and CD8 + T cells specific for TB bacteria.

Upregulated genes clustered into at least 7 functional groups, including immediate early genes or transcription factors, cell - cycle related genes, stress - responsive protein genes, cell signaling protein genes, cell adhesion and cell surface protein genes, genes involved in translation and protein turnover, and genes encoding metabolic proteins.

In order to identify potentially important, novel extracellular protein interactions I am carrying out high - throughput protein - protein interaction screens, using large libraries of recombinant sporozoite and human cell surface proteins.

Optimize protocols for culturing and maintaining Hela cells, identifying and characterizing proteins, enrichment of integral membrane proteins from mammalian tissue, biotinylation and isolation of mammalian cell surface proteins, and isotope metabolic protein labeling, quantization of protein expression levels from differentially treated cell populations.

Positive selection of developing thymocytes is associated with changes in cell function, at least in part caused by alterations in expression of cell surface proteins.

Known as MHC (Major Histocompatibility Complex) genes, they code for cell surface proteins.

The protein is important because it is similar in structure to cell surface proteins in several pathogenic fungi.

In the case of additional labelling of specific cell surface proteins, primary antibodies were added at a dilution of 1 ∶ 1000 to cells resuspended in FACs buffer.

In another study, Rezende helped functionally characterize the specific fragments of the cell surface protein, Als5p, that allows the pathogenic fungus, Candida albicans, to bind to its host.

In one project, she studied a-agglutinin, a cell surface protein that mediates cell interaction and mating for Saccharomyces cerevisiae — baker's yeast.

Unlike CD8 + DCs that express the cell surface protein CD205, CD8 — DCs, which are positive for the 33D1 antigen, are specialized for presentation on major histocompatibility complex (MHC) class II.

CRH, in turn, triggered production of the cell surface protein FasL; trophoblasts expressing FasL then form a protective shield of sorts around the embryo by forcing any attacking immune cells to self - destruct.

Some would simply crank their telomerase activity up even further; some would enhance the activity of drug - metabolizing enzymes that degrade the inhibitor; still others would change their cell surface proteins in ways that would make it harder for the drug to penetrate into the cell.

A group of cell surface proteins, designated Aplysia cell adhesion molecules (apCAM's) was down - regulated in the sensory neurons in response to serotonin.

They found that an aggressive breast cancer tumor cell has a cell surface protein called «beta2 - adrenoceptor» that can binds both beta - blockers and the stress hormone adrenaline.

The data referred to cell surface proteins that supposedly defined the cells.

A cell can change the amount of these cell surface proteins by internalizing small portions of the membrane through endocytosis.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

STAR2 works by specifically binding to a cell surface protein called TNFR2, activating a signaling pathway that increases the number of T reg cells.

A group of variants unique to the Hadza spanned the DNA encoding for a cannabinoid receptor, a cell surface protein that responds to tetrahydrocannabinol — the active ingredient in marijuana — which is intriguing because Tishkoff's team observed that the Hadza smoke large amounts of marijuana.

Asialoglycoprotein receptor 1 (ASGPR1) is another liver - specific cell surface protein and a marker for mature hepatocytes (Takayama et al. 2014; Peters et al. 2016).

Breast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as...

«For example, cell surface proteins that respond to growth factors can be deregulated in some cancers.»

These studies led to identification of a cell surface protein that is a useful marker of positive selection and is a likely regulator of mature lymphocyte and APC function.

The experiments identified a previously uncharacterized gene as essential for intoxication by diphtheria toxin and exotoxin A toxicity, and a cell surface protein needed for cytolethal distending toxin toxicity.

In pathogens like yeast, these cell surface proteins regulate how the cell sticks to other cells, interacts with surrounding tissue and evades detection by the immune system.

FACS - if you're knocking out a cell surface protein, then cell sorting can be used to rapidly isolate those clones that have lost the protein of interest

Twenty - five additional genes that were upregulated during late schizogony, and predicted to encode secreted and cell surface proteins, were identified and expressed as soluble recombinant proteins.

A library of recombinant P. falciparum secreted and cell surface proteins was expanded by 20 additional proteins, which were shown to express at usable levels and contain conformational epitopes.

People who had a better antibody response to the vaccine after 28 days had higher levels of HLA - DR (a cell surface protein which is a marker for immune stimulation) on a specialised type of dendritic cell.

Prior to vaccination, these people also had more B cells in their blood with more CD86 (a cell surface protein that allows the immune system to be activated quickly in response to a threat).

Chemicals in these particular types of leafy green vegetables trigger a powerful immune boosting activity in cell surface proteins (AhR proteins) found on the surface of white blood cells, otherwise known as lymphocytes.