Sentences with phrase «into brain cells»

Seeking the next best thing, scientists have found ways to transform skin cells into brain cells.

From there, researchers can prompt the stem cells to turn into brain cells for further study.

The first step in the process involves inserting into those brain cells a gene that makes a light - sensitive protein.

By adding the proper nutrients, the researchers could not only spur these stem cells to grow into brain cells — done for more than a decade — but to form little balls.

People already have ways to put proteins into brain cells.

Other studies have shown that the virus is capable of moving into brain cells, modifying the regulation of the cell cycle, and inducing their death.

The epigenetic programming established during development is normally quite stable (skin cells do not spontaneously turn into brain cells during adult life), but it is not irreversible.

Two teams turned embryonic stem cells into brain cells, stained differently in these pictures.

Some researchers have been trying an alternative route: engineering gene - delivery vehicles such as viruses to transfer neurotrophic - factor genes directly into brain cells.

Zheng, together with Leah Boyer, then a researcher in Gage's lab and now director of Salk's Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a dish.

«We're looking at bacteria that make magnetic nanoparticles, so we can insert their genes into brain cells in the same way,» Pralle says.

The other (somatic) cells differentiate into brain cells, muscle cells, etc..

Some worry that such human cells, when combined with animal embryos, could develop into brain cells, sperm, or egg cells in the chimeric offspring.

«Altering Huntington's patients» skin cells into brain cells sheds light on disease: Reprogrammed brain cells exhibit «symptoms» of fatal disorder.»

People once confined to wheelchairs because of stroke showed improvements in movement and speech with the help of stem cells injected into the brain

Scientists at Columbia's Zuckerman Institute have uncovered new insights into how stem cells transform into brain cells that control leg movements.

The scientists collected skin cells from 19 people, aged from birth to 89, and prompted them to turn into brain cells using both the induced pluripotent stem cell technique and the direct conversion approach.

If a memory is wired into brain cells — a literal engraving of information — then why is it so easy to alter many years after the fact?

Originally from algae, the gene makes a protein called channelrhodopsin - 2, which reacts to blue light by admitting ions into the brain cells, activating them in the process.

In turn, hyper - activated TLR3 turns off genes that stem cells need to specialize into brain cells and turns on genes that trigger cell suicide.

However, in developing brain cells, the researchers found TLR3 activation also influences 41 genes that add up to a double whammy in this model — diminished stem cell differentiation into brain cells and increased cell suicide, a carefully controlled process known as apoptosis.

«Excitingly, we have been able to demonstrate that just the SIRT1 molecule, once re-introduced into brain cells, was capable to recapitulate almost the same identical features of calorie restriction,» says Pasinetti.

When FGFR - TACC was introduced into the brain cells of healthy mice, aggressive brain tumors developed in 90 percent of the animals, confirming that this gene fusion can lead to glioblastoma.

A cellular protein called PAK1 stimulates the growth of dendritic spines, or protrusions, that allow communication between neurons, and Roy had a hunch that this protein — when transported into brain cells — might help bring silent engrams back into direct awareness.

From there, the ASOs get taken up into brain cells where they continue to suppress their target protein for a month or so, after which time more needs to be injected.

The discovery was made when researchers added concentrated quantities of lysine and arginine into brain cells, and then any microscopic reactions were made visible by making the brain cells fluorescent.

Therefore, when lack of sleep occurs, and your brain is unable to properly respond to insulin (which drives glucose into brain cells) your brain becomes desperate for carbohydrates to keep going.

Interesting though is the increase in free radical damage from too much glutamate allowing too much calcium into brain cells, so neurons fire too rapidly, and die.

It acts by binding to specific receptors and allowing sodium (Na +) or calcium (Ca +) to move into brain cells through channels.

Recently, Dr. Ding achieved entirely gene - free chemical reprogramming, using only drugs to turn fibroblasts directly into brain cells.

The team used a technique called optogenetics, in which light - responsive proteins are genetically inserted into brain cells, allowing researchers to activate them with lasers to find out what they do.

The basic recipe takes human stem cells, makes them differentiate into brain cells, and lets them grow into entities a few millimeters across that mimic the structure, cell populations, and even the electrical activity of the full - blown version.

He inserts light - sensitive proteins into brain cells.

Inserting genes into brain cells may one day offer doctors a way to slow, or even reverse, the damage from degenerative neurological disease

The team at the University's Medical Research Council Centre for Regenerative Medicine were surprised to find the molecules can also boost direct conversions from one type of mature cell to another — including transforming skin cells into brain cells.

This blood - brain barrier is a formidable obstacle to delivering certain types of treatments for neurological diseases, but Manjunath N. Swamy and his team at Harvard Medical School's Immune Disease Institute devised a clever way to sneak a drug through and insert it directly into brain cells.

During the past decade, Boyden and others have found ways to snip the microbial genes that code for the light - sensitive proteins and insert them into brain cells, thus making those neurons also responsive to light.

Methylmercury crosses the protective blood - brain barrier by binding with an essential amino acid that has dedicated carrier proteins for shunting it into brain cells.

The procedures required for converting the stem cells into brain cells were developed by Anna Monzel as part of her doctoral thesis, which she is doing in Schwamborn's group.

A new technique that converts stem cells into brain cells has been developed by researchers at Lund University.

The advantages of this approach began to emerge in 2011, when Dr. Ding announced that he had used his «chemical reprogramming» method to convert human skin cells into brain cells.

Clive Svendsen from Cedars Sinai introduces the work of the HD iPSC Consortium - a group of scientists working on turning skin cells into brain cells.

«New Genetic Technique Converts Skin Cells Into Brain Cells.»

Stem cells allow researchers to collect blood or skin samples from living patients and turn them into the brain cells affected by the disease — neural progenitor cells (NPCs) and neurons.

Researchers are using genetic engineering and growth factors to reprogram the skin cells of patients with schizophrenia, autism, and other neurological disorders and grow them into brain cells in the laboratory.

SAN FRANCISCO, CA — A scientist at the Gladstone Institutes has discovered a novel way to convert human skin cells into brain cells, advancing medicine and human health by offering new hope for regenerative medicine and personalized drug discovery and development.

In the experiments being reported today, Dr. Ding used two genes and a microRNA to convert a skin sample from a 55 - year - old woman directly into brain cells.

Even cooler, scientists are now able to «reprogram» human skin cells from patients with neurological disorders and grow them into brain cells [source: Kavli Foundation].