Sentences with word «polymorphism»

Single nucleotide polymorphisms in genes for 2» -5» - oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection.J Infect Dis.

Genome - wide patterns of nucleotide polymorphism in domesticated rice Caicedo, A. L., S. H. Williamson, R. D. Hernandez, A. Boyko et al. 2007.

I am interested in understanding how genetic polymorphisms in genes encoding PTPs can mediate disease pathogenesis, and in defining new drug targets for immune - mediated diseases among the PTPome.

Association analysis of the catechol - o - methyltransferase (COMT), serotonin transporter (5 - HTT) and serotonin 2A receptor (5HT2A) gene polymorphisms with obsessive - compulsive disorder

This form of vitamin B9 is bioavailable to those of us with polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene C677T, which is associated with assorted autoimmune diseases and mood disorders such as depression and schizophrenia (Cevik et al., 2014; Stover et al., 2017).

In relation to the association of infant attachment with a promoter polymorphism of the serotonin transporter gene, we have mentioned that gene expression may be affected by variation in the DNA sequence of the regulatory region of the gene.

The novel variations, dubbed «multiple nucleotide length polymorphisms,» or MNLPs, altered transcription of the genes they were associated with as much as 11-fold.

Novelty seeking and dopamine receptor polymorphisms in adolescence Noa Heiman, Institute for Behavioral Genetics, University of Colorado, Boulder, USA

DNA samples were genotyped for polymorphisms of 5 - HTTLPR, DRD4 exon III variable number tandem repeat, and DRD4 - 521.

Lectin may cause leptin resistance, affecting its functions (signal have high levels of leptin and several effects gathering to protect from lipid overload), as indicated by studies on effects of single nucleotide polymorphisms on the function of leptin and the leptin receptor.

Significance of serotonin transporter gene 5 ′ - HTTLPR and variable number of repeat polymorphism in attention - deficit / hyperactivity disorder

Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data Bustamante, C. D., R. Nielsen, and D. L. Hartl.

Brain - Derived Neurotrophic Factor val66met Polymorphism Affects Human Memory - Related Hippocampal Activity and Predicts Memory Performance

The researchers looked at functional single nucleotide polymorphisms within the CLOCK gene that are able to influence how much protein is transcribed from the gene.

Estimating population divergence time and phylogeny from single ‐ nucleotide polymorphisms data with outgroup ascertainment bias.

Secondly, a single protein can crystallize in multiple different crystal forms, this is known as polymorphism.

In one 5 - HTTLPR polymorphism study differences were seen between men and women: healthy men became more impulsive, whereas healthy women showed a mood reduction after ATD.

Further, existing research has been limited to one or two functional polymorphisms at the expense of a more comprehensive assessment of the serotonin system.

Gene mutations such as MTHFR polymorphism can inhibit your body's ability to bring down inflammation levels, such as homocysteine.

In contrast, among nonmaltreated infants, 5 - HTTLPR and DRD4 polymorphisms influenced attachment security and disorganization at age 2 and the stability of attachment disorganization over time.

Additionally, this group also assessed the relationship of the A118G polymorphism to neural response during an actual episode of rejection in which the participant was excluded from an online ball - tossing game (Cyberball) with two supposed others.

Discovery of a ligand that compensates for decreased endogenous agonist potency of melanocortin - 4 receptor polymorphisms identified in obese humans.

But nearly everyone also has variants (often called polymorphisms) that are deemed benign — and companies typically don't send clients information about those variants.

Similarly, in cancer genomics, a candidate somatic mutation observed at the position of a known polymorphism typically indicated a germline variant that was under - called in the normal sample.

Scientists think humans carry tens or even hundreds of related polymorphisms.

Rounding out the session were presentations from GenoMEL scientists from the United States, the Netherlands, Mexico, Scotland and Austria, including an update on the most recent GenoMEL genomewide association study of genetic variants called single nucleotide polymorphisms associated with increased risk of developing melanoma in the general population.

Estrogen receptor beta gene +1730 G / A polymorphism in women with polycystic ovary syndrome.

Martin and Palumbi did this, using a technique known as restriction fragment length polymorphism analysis.

In the Diabetes Prevention Program, SHBG and SHBG - single nucleotide polymorphisms did not predict incident diabetes in any sex, but diabetes incidence was directly associated with estradiol and estron and inversely with testosterone in men (62).

Obsessive - compulsive disorder and the promoter region polymorphism (5 - HTTLPR) in the serotonin transporter gene (SLC6A4): a negative association study in the Afrikaner population

HIV - 1 Env gp120 C2V5 Potential N - Linked Glycosylation Site (s)(PNGs) Variations and Amino Acid Length Polymorphisms among Infected Family Members

Genotype and allele frequencies of the MTHFR +677 C / T and +1298 A / C polymorphisms showed no significant differences between healthy controls and patients with AITD; these genotype and allele frequencies did not influence the prognosis of AITD.

She has published over 90 articles in the human genetics literature that focus on the discovery and analysis of DNA sequence polymorphism.