Sentences with phrase «by cancer cells»

Meanwhile, fructose appears to be preferred by cancer cells for cell division, which contributes to its growth and spreading throughout your body.

The unusual supply lines built by cancer cells may explain why some treatments fail and offer new targets for drugs.

But the drugs have been limited by cancer cells ability to development resistance, as well as the inhibitors inability to fight solid tumors effectively.

Secondary rounds of tumor sequencing — possible now that the cost has fallen dramatically — could point to new mutations acquired by their cancer cells, thus suggesting further treatments.

Too much growth factor production by some cancer cells helps them grow quickly.

What hasn't been understood until now is whether this excess sugar consumption by cancer cells is a symptom of cancer, or if it's a cause of cancer.

In fact, while fats can be used as an energy source by normal dog cells, they can not by cancer cells.

Ketones, on the other hand, can't be used by cancer cells as an energy source.

There may also be a blood test for a substance produced by some cancer cells called carcinoembryonic antigen (CEA).

The research team will conduct clinical trials to evaluate a novel immunotherapy treatment which combines a molecule expressed by cancer cells with a modified live form of the bacteria Listeria monocytogenes.

MicroRNAs secreted by cancer cells can alter the expression of genes in non-cancerous cells, disrupting their normal function and promoting tumor growth.

The project, done in collaboration with a medical researcher, delved into O (6)- alkylguanine - DNA alkyltransferase (AGT), a DNA repair protein that is hijacked by cancer cells as a way to resist DNA - damaging chemotherapy agents.

An inactive metallic nanoparticle containing iron, silver, or gold is absorbed by a cancer cell.

Nasal adenocarcinoma is a slow, progressive, local infiltration by cancer cells of tissues lining the inside of the nose.

Now, in a new study using laboratory - grown cells and mice, Johns Hopkins scientists report that a method they used to track metabolic pathways heavily favored by cancer cells provides scientific evidence for combining anti-cancer drugs, including one in a nanoparticle format developed at Johns Hopkins, that specifically target those pathways.

«Brain metastases are a secondary brain tumour, which means they are caused by cancer cells that escape from primary tumours like lung, breast or melanoma, and travel to the brain,» said Mohini Singh, the study's primary author and a PhD candidate in biochemistry at the Michael G. DeGroote School of Medicine at McMaster.

Knowing more about the activation process has led researchers to be able to induce greater vulnerability by cancer cells to an existing first - line treatment for cancers (mainly lung) driven by a receptor called EGFR.

«We found that inhibiting an enzyme that adds the fatty acid palmitate onto proteins creates dependence by cancer cells on EGFR signaling for survival,» Witze said.

Just as cells of the immune system use antibodies to recognize pathogens, researchers in this study designed antibodies to recognize a protein over-expressed by these cancer cells, namely the protein mesothelin.

The research team suggests that this normal contact between the two cell types is exploited by cancer cells, in which contact - based, mutually reinforcing cross-talk between them turns off the immune response.

To try to block this «hacking» of the microenvironment by the cancer cells, the team turned to a drug called JQ1, which is known to block the epigenome changes that they'd observed.

«Some studies suggested that exosomes harbored the potential to regulate cancer cell metabolism, but most research had focused on the exosomes that were produced and emitted by cancer cells themselves.

These include several «cancer - testis» antigens, which are expressed only by cancer cells and not by healthy tissues (with the exception of the testis and, occasionally, placenta), making them promising targets for cancer immunotherapy.

The microscope has been used to peer inside blood vessels being invaded by cancer cells and capture white blood cells while they chomp down on sugars inside a fish eyeball.

It's possible that inherited regions of CNV with strong influence on gene expression are targeted for amplification / deletion by cancer cells, which might obscure their effect in an otherwise normal cell.

The research, published in Cell Metabolism, identified the role of a particular protein, IL - 6, released by cancer cells even before cachexia manifests.

Researchers at the Institut Curie in Paris now say that they have evidence of a coordinated attack on the basement membrane by cancer cells in situ and CAF cells in the extracellular matrix that begins long before the actual translocation of cancer cells.

Through such evolutionary processes, a drug that targets telomerase could seem effective at first, only to be defeated by the cancer cell line if it can (for instance) more effectively break the drug down, or prevent the drug from entering its cells, or put out the biological equivalents of the «chaff» and flares that are used by fighter jets to ward off the targeting systems of hostile missiles.

The University of North Carolina at Chapel Hill, Washington University School of Medicine in St. Louis, and Boise State University have been named partners in one of five U.S. centers that will use genetic data to search for proteins that are abnormally made by cancer cells.

After omega - 3s are digested by a cancer cell, the fatty acid is split up into smaller molecules know as metabolites.

The study has also suggested that the Eugenol in clove has anti-mutagenic properties, and it inhibits genotoxicity induced by cancer cells.

But because metformin may stem cancer through several different channels — by lowering insulin, directly slowing tumor growth, or promoting suicide by cancer cells — it could potentially prove useful in many types of cancer.

A route frequently used by cancer cells for dissemination is the lymphatic system.

Designing molecules that selectively target thiols produced by cancer cells that cause drug resistance is the focus of many years» work by Dimmock, Das and their collaborators.

«We found that exomeres are the most predominant particle secreted by cancer cells,» said senior author Dr. David Lyden, the Stavros S. Niarchos Professor in Pediatric Cardiology, and a scientist in the Sandra and Edward Meyer Cancer Center and the Gale and Ira Drukier Institute for Children's Health at Weill Cornell Medicine.

One miRNA can target multiple genes, but their expression is often hijacked by cancer cells and disrupts multiple cancer - causing or tumor - suppressing pathways,» says Shuk - Mei Ho, PhD, director of the CCC and Jacob G. Schmidlapp Chair of Environmental Health and professor at the University of Cincinnati (UC) College of Medicine.

However, if the ionic colloidal silver is absorbed by a cancer cell, it may disable the pathogen inside the cell, thus allowing the cell to revert back to a normal cell.

The protein, Aiolos, is produced by normal blood cells but commits a kind of «identity theft» of blood cells when expressed by cancer cells, allowing the latter to metastasize, or spread, to other parts of the body.

«We think some of these genes could be «hijacked» by cancer cells and may contribute to the shared invasive characteristics of the placenta and cancer,» Sutherland says.

Targeting stromal cells as well as the cancer cells blocks multiple cell signalling pathways that are used by cancer cells to become aggressive.

But work by Pollard and other researchers has detailed how macrophages are «reeducated» by cancer cells to do their bidding.

In therapy, a patient's T cells are removed and engineered to express chimeric antigen receptors (CARs), which specifically target proteins expressed by cancer cells.

The PKCƐ signal pathway, which is used by cancer cells but rarely by normal cells, could be important in targeting some cancer cells as they rely on this pathway to survive.

«Scientists pinpoint a new line of defense used by cancer cells.»

Cancer Research UK scientists have discovered a new line of defence used by cancer cells to evade cell death, according to research published in Nature Communications.