Sentences with phrase «cell sequencing»

Development of methodology to facilitate single cell studies of structural variation, and integrating state - of - the - art microscopy methods with single cell sequencing.

The new platform processes hundreds to tens of thousands of cells per day, providing scalable, sensitive, single - cell sequencing with simple yet powerful data analysis.

He also recommends performing standard bulk - cell sequencing on a portion of the sample, to provide a basis for comparison with the single - cell DNA data.

As equipment makers and service providers try to make single - cell sequencing accessible to more labs, scientists at the forefront of the field are pushing the technique into entirely new territory.

Should patents on gene cell sequences follow the classical model of patent claims or be limited to specific uses («purpose - bound protection»)?

Our scientists developed a new method for single cell sequencing.

A new study used single cell sequencing technology to provide previously unknown details about how and when CNAs impact tumor formation and growth, information that may have significant implications for diagnosis and treatment.

As a response to the growing demand for single cell sequencing projects, in July 2016, the Single Cell Facility at the Hubrecht Institute was founded.

The Illumina Bio-Rad Single - Cell Sequencing Solution comprises the new Bio-Rad ddSEQ Single - Cell Isolator and Illumina Bio-Rad SureCell WTA 3 ′ Library Prep Kits.

Watson School awards seven Ph.D. degrees, to students who studied topics ranging from single - cell sequence data analysis to acute myeloid leukemia...

The depth of insight is limited only by the numbers of cells sequenced and cheaper sequencing will enable us to see far back to the early stages of life, and study inter-individual variation in development.

On a similar note, the latest single cell sequencing methods based on stochastic schemes for in situ barcoding of cells are impossible to assess with negative control samples.

These include sophisticated chromosome engineering techniques as well as applications of large - scale RNAi and CRISPR screens to identify both driver genes and tumor - cell - specific dependencies, as well as single cell sequencing approaches.

In the last couple years, however, hundreds of youngsters with cancer have had the DNA in their noncancerous cells sequenced.

In the study, researchers quickly matched a strain of leukemic cells sequenced by the MinION against a reference file in the Cancer Cell Line Encyclopedia database, they report.

Information obtained via single - cell sequencing from cells sampled from each core indicate the likely location of a cancerous tumor (dotted lines encompassing cores 2, 3 and 6).

Philippa Harding and Anna Wilbrey - Clark from Kerstin Meyer's team at the Sanger Institute processed and single - cell sequenced separate parts of the spleen at four different time points.

Einstein Researchers Publish Single - Cell Sequencing Prep Method, Launch Firm to Provide Service - Genomeweb, April 2017

«We found several distinctions between sensitive and resistant models detected at the single - cell level, which testified to single - cell sequencing potential usefulness for understanding how these cancers may develop resistance.»

My PhD project (ESR 1) will focus upon the extension of our knowledge of the biodiversity of the hidden heterotrophic micro-eukaryotes using single cell sequencing technology.

The diversity of genome amplification options underscores the importance of having a clear experimental question in mind before starting a single - cell sequencing project.

In this presentation, we will discuss how the Illumina Bio-Rad Single - Cell Sequencing Solution combined with the Bio-Rad S3e Cell Sorter enhances single - cell studies and provides researchers with a robust, scalable, and user - friendly workflow that enables transcriptome profiling of hundreds to tens of thousands of single cells in a single experiment.

Co-first author Alice Eunjung Lee, PhD, from the lab of Peter Park, PhD, at the Center for Biomedical Informatics at Harvard Medical School, developed the study's retrotransposon analysis tool, which detects somatic retrotransposon mutations in single - cell sequencing data.

CITE - seq is compatible with existing single - cell sequencing approaches and will readily scale as the throughput of scRNA - seq methods increases.

In addition, Rubin pointed to the advent of single - cell sequencing with microfluidic and cell sorting approaches, focused specifically on cells that lack genes that match previously identified ones, as another approach in the search for completely novel organisms.

For this purpose we apply single - cell sequencing methods and single - molecule FISH.

A new study used single cell sequencing technology to provide previously...

We believe it's very hard to treat a disease if you can't understand it, so we spend a lot of time and effort thinking about the underlying components of diseases, which can include large - scale sequencing, single - cell sequencing, and disease profiling.

The goal here is to use «single - cell sequencing to understand how many different cell types there are in the human body, where they reside, and what they do,» as Nature reports.

Besides keeping the cells intact, the flow - based system also allows investigators to isolate them for single - cell sequencing or other analyses.

«Whole - genome, single - cell [sequencing] costs about the same as bulk - cell sequencing,» says BGI's Peng.

As costs come down and methods become more standardized, experts in the field expect single - cell sequencing to become the new model for both transcriptomic and genomic studies.

«Whole - genome, single - cell [sequencing] costs about the same as bulk - cell sequencing.»

The need to compare multiple cells» DNA sequences to distinguish genuine genetic variants from artifacts limits some of the potential of single - cell sequencing.

Hiring contractors to handle the entire process is especially useful for researchers new to single - cell sequencing.

This study marks the first time that a technique called single - cell sequencing has been used to examine individual cells from mouse embryos in the early stages of development.

«To address this problem we combined single - cell sequencing with targeted single - molecule deep sequencing.

That's roughly a 40-fold increase in throughput from the existing method of single - cell sequencing.

This led to development of newer technology, called single cell sequencing (SCS), that has had a major impact in many areas of biology, including cancer research, neurobiology, microbiology, and immunology, and has greatly improved understanding of certain tumor characteristics in cancer.

Existing technology, known as next - generation sequencing (NGS), measures genomes derived from millions of cells versus the newer method for single - cell sequencing, called Monovar.

To accomplish this, the researchers modified analytical techniques specialized at finding shared patterns across images — for example, to align facial visualizations across different lighting conditions for single - cell sequencing data.

Using methods such as single cell sequencing, proteomics, and microscopy will allow exploration of this invisible and important world with great accuracy and depth.»

This includes the development of advanced laboratory tools such as CRISPR genome - editing and single - cell sequencing technologies.

The field of single - cell sequencing is rapidly expanding, with the potential to precisely study how the basic building blocks of life function and evolve.

Using single - cell sequencing, the expression patterns of independent cells can be investigated by examining their own sequence information.

As a response to the growing demand for single cell sequencing projects, in July 2016, the Single Cell Sequencing Facility at the Hubrecht Institute was founded.

A brand new 3D printed, portable, and low - cost microfluidic controller has been developed by NYGC and NYU, enabling single - cell sequencing to become a lot more accessible.

SPAdes: a new genome assembly algorithm and its applications to single - cell sequencing.

The Korbel group combines experimental and computational approaches, including single - cell sequencing technology, to unravel determinants and consequences of germline and somatic genetic variation.