Sentences with phrase «from embryonic stem cells»

Last week British scientists announced that they had created sperm cells from embryonic stem cells for the first time.

The mouse was grown from embryonic stem cells that contained foreign DNA coding for antibiotic resistance.

The success is thanks to neurons cultivated from embryonic stem cells and the right «cocktail» of ingredients to guide cell development.

If the trial is successful, by 2018 the researchers hope to begin trialling the use of dopamine cells derived from embryonic stem cells through a new collaboration with teams across Europe, the USA and Japan.

Neuroscientist Ron McKay, of the National Institutes of Neurological Disorders and Stroke in Bethesda, Maryland, and other researchers have figured out how to grow dopamine - producing cells from embryonic stem cells in culture dishes, but with Isacson's method, «you just take cells and put them in the brain,» says McKay.

Mice generated from embryonic stem cells in which ion channel genes have been mutated by homologous recombination often have a perfectly normal heart.

For John Fink, a professor in the U-M Medical School Department of Neurology who has studied and treated genetic nerve - destroying conditions for decades, the new availability of nerve cells made from embryonic stem cells is priceless.

This has always been a worry with tissues produced from embryonic stem cells, as these have the capability to form tumours if any are left in their original state in the transplanted tissue.

(In many ways it is worse than when John Edwards said in 2004 that if people voted for John Kerry, people like Christopher Reeve would get out of their wheelchairs and walk from embryonic stem cell therapies.)

A pluripotent state makes the resulting cells indistinguishable from embryonic stem cells, and the scientists got these cells without creating or destroying any embryos.

The scientists first compared mouse megakaryocyte cells created from embryonic stem cells engineered to lack p45 - Nfe2 with normal megakaryocytes.

For example, a consortium of research groups called the London Project to Cure Blindness aims to test RPE transplants from embryonic stem cells in patients with macular degeneration this year.

Further study, however, revealed cells derived from iPS cells had significantly higher rates of cell death, or apoptosis, than ones from embryonic stem cells.

However, he believes that cloning embryos for the purpose of making medically useful tissues from embryonic stem cells is still a supportable strategy.

Following this, they demonstrated that neural progenitors from embryonic stem cells could differentiate themselves into neurons in rat brains presenting lesions similar to those observed in humans.

Renee Reijo Pera, a biologist at Stanford's Institute for Stem Cell Biology and Regenerative Medicine, points out that earlier attempts to create offspring with sperm from embryonic stem cells resulted in short - lived mouse pups that were either giants or midgets.

The researchers say that they can grow the stomach organoids from both embryonic stem cells and skin cells induced to pluripotency.

Tiny brains grown in the lab from embryonic stem cells — so - called organoids — were pioneered in the last decade by Profs. Yoshiki Sasai in Japan and Juergen Knoblich in Austria.

The other group was created by implanting eggs with nuclei from embryonic stem cells — the as - yet - undifferentiated cells of very early embryos.

Researchers compared induced pluripotent stem cells lines reprogrammed from different adult cell types that have been previously differentiated from embryonic stem cells.

«Unfortunately, the availability of human fetal tissue is extremely limited, and the creation of OPCs from embryonic stem cells is slow and tedious,» said the study's senior author, Marius Wernig, MD, assistant professor of pathology and a member of Stanford's Institute for Stem Cell Biology and Regenerative Medicine.

The IMPC envisages a ten year programme to undertake a broad - based, systematic genome - wide phenotyping project of knockout mice generated from the embryonic stem cell mutant resources developed by the International Knock - out Mouse Consortium (IKMC).

Improved production of retinal cells from embryonic stem cells brings this therapy closer to the clinic.

In addition, we use our expertise to facilitate the development of functionally mature beta cells from embryonic stem cells for cell replacement therapies of type 1 diabetes.

A team of UK stem cell scientists, led by Dr. Robin Ali from UCL Institute of Ophthalmology in London, has developed a new strategy for repairing the retina by transplanting photoreceptor cells generated in the laboratory from embryonic stem cells.

A scientific researcher extracts the RNA from embryonic stem cells in a laboratory, at the University of Sao Paulo's human genome research center in Brazil.

Researchers find that Insulin - like growth factor / Insulin - mediated induction of mesodermal differentiation aids the production of cardiac progenitor cells from embryonic stem cells towards a strategy to boost cardiac cell production.

And so it's really great that embryonic stem cell research was there for us, and also that most of these leads that we're talking about today came from embryonic stem cell research.

In 2006, Wisconsin's governor dedicated $ 1 million for creating blood products from embryonic stem cells.

At first they found that human iPS cells could indeed generate blood vessel, blood precursor and retinal cells with characteristics similar to ones derived from embryonic stem cells, albeit with significantly reduced efficiency.

Recently, heart cells have been grown from embryonic stem cells in Israel.

In people with severe eye disease, transplants made from embryonic stem cells (in region of black dotted circle) appear safe, and became larger and more pigmented over time (right).

Scientists this week reported major advances toward a central goal of stem cell research: directly reprogramming fetal mouse cells so that they are indistinguishable from embryonic stem cells.

Although organoids can also be created from embryonic stem cells, an organoid derived from a patient's own cells carries the complete genome of that person.

The answer to this question comes from the lab of Marcel Leist (University of Konstanz, Germany) and their studies employing a defined and controllable in vitro system of post-mitotic murine astrocytes generated from embryonic stem cells (mAGES)[1].

Newcastle University and the NorthEast England Stem Cell Institute are aware that the research paper «Derivation of Human Sperm from Embryonic Stem Cells» by a group led by Professor Karim Nayernia has been withdrawn from the academic journal Stem Cells and Development.

Muscle cells are stained green in this micrograph of cells grown from embryonic stem cells in the lab of Masatoshi Suzuki at the University of Wisconsin — Madison.

For the purpose of additional experiments, the researchers generated myocardial cells from embryonic stem cells and human skin cells, in collaboration with the lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.

From the embryonic stem cells, the researchers produced a type of tissue called retinal pigment epithelium (RPE).

Two people have been given implants of cells derived from embryonic stem cells that may be able to release insulin when needed to manage blood sugar levels

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

Freed expects transplants of neurons derived from embryonic stem cells to enter the clinical arena soon as well.

A team led by Afsaneh Gaillard (Inserm Unit 1084, Experimental and Clinical Neurosciences Laboratory, University of Poitiers), in collaboration with the Institute of Interdisciplinary Research in Human and Molecular Biology (IRIBHM) in Brussels, has just taken an important step in the area of cell therapy: repairing the cerebral cortex of the adult mouse using a graft of cortical neurons derived from embryonic stem cells.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.

Muscle cells are stained green in this micrograph of cells grown from embryonic stem cells.

Dr. Weir is supervising investigations to uncover the processes by which pancreatic precursor cells derived from embryonic stem cells and other sources mature into fully active beta cells when transplanted into mice.

KOMP2 and IMPC researchers will begin by creating lines of knockout mice from embryonic stem cells produced by KOMP.

The current paper builds a bridge between the nurse and building block approaches, because the researchers mix two complementary types of cells: an angiogenic one derived from bone marrow cells that expands existing blood vessels, and a vasculogenic one derived from embryonic stem cells that drives formation of new blood vessels. Note: embryonic stem cells were of mouse origin, not human.

In fact, therapies from embryonic stem cells haven't even cleared stage - one clinical trials.