Sentences with word «infectivity»
Because we lack serology data on people in regions of Ebola outbreaks, it is not known whether there are infected individuals who remain asymptomatic; therefore, the degree of infectivity of the virus is unknown.
genomemedicine.biomedcentral.com
Once we get through the public health crisis phase of things, that's going to be one of the important research questions: to look at differences in infectivity in one species and another.
What is the effect of the HIV - 2 accessory protein Vpx on HIV infectivity and the cell death pathway in lymphoid CD4 T cells?
They find statistical support for high viral infectivity rates of dengue serotypes 2 and 3 relative to dengue 1.
Our synthetic loops showed almost exactly the same patterns of infectivity as their natural counterparts had.
«In vitro cell culture infectivity assay for human noroviruses.»
«In our challenge experiments to test infectivity, we are stressing the animals with salt conditions and temperature to determine if this environmental stress makes them more susceptible,» Wessel said.
Investigators also have a variety of specialized resources for testing virus infectivity in various bugs and animals, sequencing viral genes and imaging pathogen structures.
The assumption that suppressing fever increases infectivity is built into the model, he says, «so it's no surprise that that is what they come up with at the end.»
Nonhuman and human primates are generally considered «dead end» hosts, so adaptation in this host may engender a phenotype of reduced infectivity for subsequent hosts; this is likely an uncontrollable characteristic of the model system, rather than an indication of the viability of the spirochetes.
«This is some clear evidence that the cells are actually being purged of prion infectivity,» says Williamson — a «pleasant surprise,» he adds, because prions had always been deemed very resilient.
Scientists are gaining an insider's look behind the notorious infectivity of Francisella tularensis.
Lentiviral particles with the VSV - G envelope have high infectivity in a wide range of cell types, so they're ideal for work with primary cells or other difficult - to - transfect cells.
To demonstrate that the defective phenotype of ospC7 was due to the lack of OspC and to determine whether reintroduction of ospC was sufficient to restore mouse infectivity, we complemented the ospC mutation in ospC7 by integrating a WT copy of ospC adjacent to the mutated ospC gene on cp26 (Fig. 1).
The limited infectivity of persisting non-cultivable B. burgdorferi has no biological significance for the natural enzootic cycle of B. burgdorferi, but it remains to be determined if they have significance in the post-treatment host.
The lower infectivity of HIV - 2 compared to HIV - 1 implies that fewer of those exposed to HIV - 2 will be infected per exposure.»
Since then, prisons have changed and the notorious policy of Viral Infectivity Restrictions (VIR), which was singled out for particularly fierce criticism in the report, has been abandoned.
ON 14 December 1967, Arthur Kornberg at Stanford University and colleagues announced that they had copied the DNA of the Phi X174 virus, producing an entity with the same infectivity as the wild virus.
«We now understand the mechanism for how 5 - aza - C blocks HIV's infectivity through hypermutation.
A different viral envelope protein (Env), usually from VSV - G due to wide infectivity, is often used as a substitute for HIV - 1 Env, which can only infect CD4 + cells.
Overall risk Tularaemia is considered to be dangerous because of its extreme infectivity and because it is easily spread.
We further hypothesized that the fitness of persistent B. burgdorferi obtained from treated and untreated animals would be evident as differences in infectivity when injected into mice.
Mouse models have provided key findings on pathogen infectivity and host responses to infection [21 — 25].
BB0844, an RpoS - Regulated Protein, Is Dispensable for Borrelia burgdorferi Infectivity and Maintenance in the Mouse - Tick Infectious Cycle
Associating proportional changes in the viral titre of nasal washes in the ferret study [16] with proportional changes in viral titres in nasal sprays in the human challenge studies [39], and taking the household SAR to approximate natural infectivity, we estimated the antipyretic - induced individual transmission enhancement factor fi using equation S22 in the electronic supplementary material.
limits viral infectivity stimulates the immune system to fight acute and...
Across populations, kiwi is used in the preparation of antimicrobial products to reduce the development of resistance towards the conventional medications for fungal and bacterial infectivity.
The threat is made even greater by the fact that the period of infectivity begins well before the very first symptoms of an infection is spotted.
This is a little more visibility than I like early on, but you can't really skip that early infectivity.
This also helps explain why 5 - aza - C is able to block HIV infectivity, despite its RNA - origin.
These will vary according to which of the two spouses is infected, the phase of the menstrual cycle during which intercourse occurs, the stage of infection and the efficacy of medication in reducing infectivity.
«Understanding the notorious infectivity of Francisella tularensis: Fresh approach to an old problem yields clues to tularemia virulence.»
Component peptide ferries virus into mucosal cells, ratcheting up infectivity as much as 100,000 times
Soto's team analyzed the retention of infectious prion protein and infectivity in wheat grass roots and leaves incubated with prion - contaminated brain material and discovered that even highly diluted amounts can bind to the roots and leaves.
Studies with extensively purified preparations demonstrated that the agent contains a protein that is required for infectivity.
In the case of Influenza A, the loss of RNA exosome activity severely compromises viral infectivity, but also manifests in human neurodegeneration suggesting that viruses target essential proteins implicated in rare disease in order to ensure continual adaptation.
Cholesterol is known to affect the virulence and infectivity of TB.
Infectivity is assayed by the ability of the virus to lyse, or dissolve, these cells when they are «plated» on a nutrient medium.
The idea is that scrapie prions might somehow interfere with the infectivity of BSE prions.
Exposure of the inactivated agent to hydroxylamine, a strong nucleophile, resulted in complete restoration of infectivity.
The low dose required for infectivity and the severity of the disease it causes had led the Centers for Disease Control and Prevention to classify F. tularensis as a Category A bioterrorism agent, and to track tularemia cases nationwide, according to Dr. Brook Peterson, a senior scientist at the UW School of Medicine who also participated in the study.
When the researchers inserted bacterial prions in yeast cells, the prions began self - propagating and multiplying, a sign of their infectivity.
But he also points out that until the retrovirus was reconstructed, its infectivity «could not be known and could not be unequivocally predicted.»