Sentences with phrase «other cell types»

For example, heart genes needs only to be turned on in heart cells, but turned off in other cell types.
The new technique could also be useful in understanding how stem cells change oxidation properties during differentiation into other cell types.
There are many other cell types of tumors and the only way to find out what it is is to have your veterinarian check it.
They tested human heart tissue and brain cells, as well as other cell types.
While blood cells live in a convenient, easily studied liquid, most other cell types have been harder to analyze in the laboratory.
But little is known about what determines which cells become neurons and which become other cell types.
Like other kinds of stem cells (which can develop into many other cell types), they can divide repeatedly.
We found that it is very selective and potent at stopping the growth of blood vessel cells without having negative effects on the growth of other cell types from the eye and elsewhere in the body.
His research focuses on chromatin, epigenetics, and small molecules to change cell fates, with a particular focus on generating new insulin - producing beta cells from other cell types.
This is basically tweaking the molecules: making small chemical changes to the compound in hopes of finding something that could block the growth of blood vessel cells initially in the culture dish without having toxic effects on other cell types.
One of these tissue types, specifically the mesoderm, develops into skeletal muscle cells (along with other cell types, including cardiac muscle, kidney cells, red blood cells, and smooth muscle).
Phagocytes — of which the macrophage is the prototypical cell but which also include a variety of other cell types such as microglia, dendritic cells, fibroblasts, and osteoclasts — play a broad role in host homeostasis in addition to host defense.
Efforts to produce other cell types, such as liver cells, have proved far more difficult, he says.
Data from the laboratory shows that signals from these molecules through their receptors control the activities and long - term survival of T cells, as well as affecting the activities of other cell types including dendritic cells, macrophages, and epithelial cells.
«At first we were surprised by how rapidly NR was able to reactivate dormant mitochondria in muscle, despite being largely consumed by other cell types,» Frederick said.
But while researchers have managed to culture other cell types, they have failed to grow the key dopamine cells needed by Parkinson's sufferers (This Week, 5 August).
Epidermal stem cells known as holoclones (shown in pink) were responsible for regenerating the young epidermolysis bullosa patient's skin, while other cell types disappeared over time.
Unlike other cell types, stem cells are unspecialized cells uniquely capable of making copies of themselves (self - renewing), differentiating into specialized cell types, and helping to maintain some tissues in the human body.
Moreover, there are yet other cell types — such as visceral adipose tissue macrophages and cytotoxic CD8 + T - cells — in which the age - related supernumerary accumulation of dysfunctional and apoptosis - resistant cells appears to play a highly deleterious role on tissue function, but where the cells are not «senescent» cells in the classical sense of p16Ink4a expression and the senescence - associated secretory profile observed in senescent fibroblasts.
A potential solution to this problem is to reprogram other cell types into functional beta - like cells, which can produce insulin but are distinct from beta cells and therefore are not recognized or attacked by the immune system.
A CHEMICAL derived from birch bark kills melanoma cells while leaving other cell types unharmed, say American scientists.
They found that, unlike in other cell types where Xist is associated tightly with the inactive X chromosome, female lymphocytes lacked this Xist «cloud,» even though the cell still contained expected levels of Xist.
It's uncertain whether other cell types, such as the immune cells that enter the lungs after an attack, have adenosine receptors — and scientists don't even know the source of the adenosine.
Most cells do not divide unless there is enough oxygen present to support their offspring, but certain cancer cells and other cell types circumvent this rule.
The team found evidence of the process in several other cell types, including breast, ovarian, umbilical cord, and kidney cancer cells.
Transplanting non-cardiac stem cells also increases the risk for tumor formation, as many of the cells turn into other cell types besides the target heart cells.
Our Intestine - Chip also allows researchers to culture intestinal epithelial cells alongside other cell types, such as immune cells, and analyze how these different cell types interact.
CDI is currently supplying embryonic stem cell - derived heart cells to California - based Roche and other pharmaceutical companies for drug screening, and hopes to create other cell types in the future.
4 - 1BB can furthermore promote expression of survival proteins in T cells, although its activities in other cell types appear to vary depending on the cell and the primary function.
When activated, these cells multiply and then transform into other cell types required to replace worn out cells under conditions of normal tissue maintenance.
The program provides accurate, rapid genotyping and chimerism analysis; automatically identifies donor and recipient peaks in post-BMT samples, calculates percent chimerism and quality metrics for single donor or double donor cases, easily appends for longitudinal monitoring post-BMT, and has multi-lineage capabilities for chimerism analysis of T - cells, B - cells, and other cell type populations.
Stem cells are unspecialized cells that have the potential to develop into other cell types during early life and growth.
In the case of cellular amino acid homeostasis, many examples will be drawn from cancer cells, for which the understanding is more complete than for other cell types.
However, it has been challenging to establish the functional importance of NMDA - Rs specifically in DA neurons for cocaine - induced synaptic AMPA - R potentiation, as opposed to a possible indirect process involving NMDA - Rs on other cell types.
The CD4 subset is capable of directing B cell responses and humoral immunity, and can modulate the actions of many other cell types including CD8 T cells, dendritic cells, macrophages, eosinophils, and basophils.
Stem cells have also been identified in human milk, and have the potential to differentiate into mammary epithelial lineages under mammary differentiation conditions in vitro, as well as other cell types in corresponding microenvironments, including bone cells, brain cells, liver cells, pancreatic beta cells and heart cells.
As part of their work, the researchers identified a «gene signature» to recognize and distinguish the enigmatic macrophages from other cell types, said researcher Christopher C. Overall, PhD, a computational biologist in UVA's Department of Neuroscience and its Center for Brain Immunology and Glia (BIG).
However, it can not be excluded that similar epigenetic effects are operative also in other cell types.
To create different cell types in the lab, stem cells must be coaxed down the road of determination — the branching paths that fetal cells normally travel to become neurons, skin cells, muscle cells, or any number of other cell types.
Gurdon overturned the prevailing idea in the 1950s that as cells specialize, they lose the genes necessary to become other cell types.
Because of the special ability of stem cells to self - renew and differentiate into other cell types, the cells could theoretically start replicating out of control and form tumors themselves.
CRAC channels control the entry of calcium into immune and other cell types, and calcium is an important intracellular signaling molecule that modulates cytokine production and the immune response.
Single - cell embryos have a unique pattern of gene expression that is characteristic of a zygote and not of any other cell type.
The researchers dialed the skin cells back, developmentally speaking, to produce induced pluripotent stem cells (iPSCs)-- a special type of cell that can both self - renew, making more iPSCs, and differentiate, specializing into almost any other cell type.
Some of the researchers at the centre will study the differentiation of stem cells into other cell types, one group by using human embryonic stem cell biology and another by studying early embryo development.

Phrases with «other cell types»

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