Sentences with phrase «drug resistance»

An analogy between the evolution of drug resistance in bacterial communities and malignant tissues.

There's been an unexpected development in our understanding of drug resistance in bacteria.

For example, bacteria would typically develop drug resistance by evolving a mutation that breaks down the drug.

Importantly, while not a cure, adding a second targeted therapy could help improve treatments by overcoming drug resistance and extending the time before the cancer returns.

One example of this work is the discovery of distinct genetic patterns of variation associated with drug resistance in malaria parasite populations.

They found they were not only ineffective, but caused drug resistance.

Scientists continue to try to stay a step ahead of the virus, both to combat drug resistance and to develop better treatments.

Ultimately, in a dramatic demonstration of acquired drug resistance, bacteria spread to the highest drug concentration.

Recent studies looking at the genome of the malaria parasite could help scientists understand how drug resistance has evolved — and develop the tools needed to keep it in check.

The new analysis includes data on drug resistance in 39 countries, and profiles of antibiotic use in 69 countries, and is the first time such data has been combined.

The researchers also plan to use this technology to study drug resistance and are developing additional platforms to guide decision making in the clinic.

On a hopeful note, he has shown that an alternative method of sewage processing seems to decrease the prevalence of bacterial drug resistance.

Almost 80 % of respondents said parasite drug resistance was an issue of concern, similar to 2012.

The finding should lead to new strategies to fight drug resistance.

New research demonstrates that manipulating competition among pathogens can lead to successful treatment with traditional drugs, even where drug resistance to that drug is already present.

As pet parents, we all need to follow any instructions given by our vets, including giving the full course of antibiotics to avoid drug resistance.

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve.

A couple of small, recently funded projects take a completely novel approach toward combating drug resistance.

This treatment strategy has substantially reduced but, importantly, not eliminated, the evolution of drug resistance within patients.

These new findings may potentially point to a «switch» to turn off this diversity — and thereby drug resistance — in cancer cells.

No significant group differences were found in children's behavior or drug resistance skills scores.

Building on research recently published in Cell Reports, the researchers identified new mutations that appeared to be driving the strong drug resistance exhibited by these tumors.

This study offers new leads that the consortium will be pursuing as to why drug resistance arises more readily in some locations when compared with others.

However, the efficacy of these two drugs dropped sharply in recent years due to the global distribution of mutant viruses carrying drug resistance.

Given that drug resistance remains a major challenge in cancer treatment overall, the findings provide important insight into an epigenetic mechanism for resistance and how it might be overcome.

These research collaborations have the power to answer questions critical to improving cancer outcomes, such as how tumors develop drug resistance, and what treatments are most effective against particular genomic traits.

That information could alert the clinician to the potential for drug resistance.

The researchers say their method offers a new explanation for how to prevent cancer cells from becoming treatment - resistant and how combinations therapies can be developed to overcome drug resistance.

Not only can that give the virus a chance to multiply, but it also can cause drug resistance, too.

By comparing this sequence with that of worms that have acquired drug resistance, the researchers expect to reveal a wealth of information about how and why resistance has occurred.

The study found several genes that are associated with resistance to antibiotics, including new genes that might point to previously unknown mechanisms of drug resistance.

The findings may point to a «switch» to turn off this diversity — and thereby drug resistance — in cancer cells.

We observe that populations from different organs (gut, plasma, lymph node, vagina) within the same macaque can be significantly different although the magnitude of the difference varies through time as drug resistance emerges.

Simply put, MDR1 is a «multi drug resistance gene» which certain breeds (including those of mixed breed heritage) carry that causes sensitivity to certain drugs.

One of William's main research themes is to assess antimalarial drug resistance in Plasmodium falciparum by comparing genetic diversity in conjunction with epidemiological factors and identifying genetic profiles which influence malaria treatment outcome.

In strains of tuberculosis that have developed drug resistance mutations, researchers have identified a secondary pathway that can be activated to reinstate drug sensitivity.

Malaria specialists worldwide say emerging drug resistance in Asia is now one of the most serious threats to that progress.

Adult drug resistant cancer cells may contribute to this problem, and the authors discuss these and other cancer drug resistance mechanisms in their recent publication in the September issue of the journal Cancers.

«Breakthrough technique combats cancer drug resistance: Researchers «turn off» multi-drug resistance capabilities in cancer cells.»

Barcoding analysis of HIV drug resistance mutations using Oxford Nanopore MinION (ONT) sequencing

Bacteria can acquire multiple drug resistance traits over time, making them resistant to several different types of antibiotics.

Today, because of concerns about drug resistance, the recommended protocol is to give ACTs only after malaria is confirmed with a finger prick of blood and a rapid diagnostic test (RDT).

Inhibitors of angiogenesis seem to be safe and, unlike conventional chemotherapy, do not induce drug resistance.

In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution.

Breeders have a number DNA tests at their disposal to check for the Multi Drug Resistance Gene, hereditary cataracts, Pelger Huet Anomaly, Collie Eye Anomaly and Progressive Rod Cone Degeneration (another eye disease), so check which testing your breeder uses.

Further, Cowen also looked at strains that had already evolved drug resistance through many different mutations.

Paweletz and his colleagues are now developing a PCR - based test to detect drug resistance mutations in lung tumors.

The mechanisms that promote or enable drug resistance include drug inactivation, drug target alteration, drug removal from cells, DNA damage repair, cell death inhibition and the epithelial - mesenchymal transition (EMT) that enable solid tumors to transform into more metastatic grades.