Sentences with phrase «sequence of a gene»

But small changes in the DNA sequences of genes occur regularly.

The presence of such sequences could provide organisms with a way to modify their gene expression without altering the actual coding sequence of genes.

They can do this by combining genes from many different organisms, or even by designing new ways to translate genetic sequences of genes into protein products.

In some cases, the missing pieces can be picked up by comparing the new sequences with known sequences of genes from other species.

DNA is composed of different sequences of our genes.

The Myriad Genetics patents on BRCA1 / BRCA2 testing, even when enforceable, covered only the targeted sequencing of those genes in cancer patients.

This cDNA lacks the non-coding «introns» found in the full sequence of a gene and is therefore not a product of nature — which is why the court ruled that it can be patented.

To solve the puzzle, he and Malaysian colleagues collected bits of the flower of Rafflesia keithii from Borneo and analyzed the DNA sequence of a gene called MatR.

Sarah Weckhuysen and colleagues report a study based on targeted sequencing of the genes encoding the components of the GATOR1 (DEPDC5, NPRL2, and NPRL3) and GATOR2 (MIOS, SEC13, SEH1L, WDR24, and WDR59) complex in European probands with focal epilepsy with or without focal cortical dysplasia.

«By analysing the first nucleotides we are able to identify which sequence of gene starts the transcription.

Wu and his colleagues compared DNA sequences of genes expressed in the brains of humans, chimpanzees, and Old World monkeys.

The patent Myriad Genetics filed in 1994, laying claim to the DNA sequence of the gene BRCA1, wasn't remarkable.

We elucidated the nucleotide sequence of a gene, and this was published in 1972.

The policy — in the form of first Office Actions on a series of applications for patents on expressed sequence tags, ESTs — could greatly complicate basic gene therapy research by substantially allowing patents for small sequences of a gene that may later be used by the patent holder to corner ownership and uses of entire genes.

That means that if a child has an undiagnosed heart disorder that may merit sequencing of a gene, the parents could, for practical and cost reasons, agree to have their son or daughter's full genome sequenced.

But to ensure that the mice only produced lysostaphin in their mammary glands, Williamson's team spliced their gene to the control sequences of another gene which works only in the mammary gland.

They conducted complete genomic sequencing of all genes implicated in breast cancer on DNA samples from breast cancer patients who had normal BRCA1 and BRCA2 commercial test results.

This is the first study in human trials to identify genes driving acute peanut allergic reactions using a double - blind placebo - controlled approach with comprehensive sequencing of genes expressed before, during, and after they ingested peanut.

siRNAs are designed by taking short sequences of the gene to be targeted and converting them into double - stranded RNA.

«This newly discovered sequence of genes enables Bacteroides ovatus to chop up xyloglucan, a major type of dietary fibre found in many vegetables — from lettuce leaves to tomato fruits.

Espinasa, L., Cahill, A., McCaffery, S., and Millar, C. (2013) Partial sequence of a gene involved in skin coloration (MC1R) from the Pennsylvanian Grotto Sculpin.

When discussing epigenetics, the actual sequence of a gene is not what scientists investigate.

As in Figure 7A, full - length protein sequences of all genes were used, except for the three proteins containing predicted transmembrane domains, ZEEL - 1, Y71A12B.17, and Y55F3C.9.

The human (and all the other) genome projects were predicated on the reasonable assumption that spelling out the full sequence of genes would reveal the source of that diversity of form and attributes that so readily distinguish worm from fly, mouse, chimp and human.

You type the DNA sequence of your gene into a database, and then you sit and you wait.

All the plant groups the researchers examined, except liverworts, contained at least one of three distinct introns — useless chunks of DNA located inside the coding sequence of a gene — in two different genes.

Daugharthy first devised an algorithm to locate the sequence of the replica DNA with the known sequence of genes in the human genome.

The classic data of bioinformatics include DNA sequences of genes or full genomes; amino acid sequences of proteins; and three - dimensional structures of proteins, nucleic acids and protein — nucleic acid complexes.

«A mutation is a permanent change in the DNA sequence of a gene, as orchestrated by God.

Blasting GM DNA into a plant arbitrarily and out of a sequence of genes that has evolved over hundreds of millions of years, in a manner aimed to optimise the functioning of an organism, is risky and unpredictable, and bound to destabilise the biochemistry of the plant.

«Epigenetic marks are physical alterations to the DNA that do not change the sequence of a gene, and thus have the potential to be reversed,» said Hurd.

Based on their previous work, they suspected that if a specific seven nucleotide stretch of an miRNA matched the sequence of a gene, that miRNA regulated that gene.

In this standard view, the genetic differences between any two individuals are due to slight differences in the sequence of their genes that mean that the genes «spell out» slightly different proteins.

Luckily, along came Armstead and his colleagues, who were working to precisely locate the sequence of a gene called staygreen (sgr) in the meadow grass Festuca pratensis, some variants of which remain green in drought and other unfavorable conditions because they are unable to break down a green pigment.

As long as you have the sequence of the gene you want to target, you're set.

Epigenetic modifications do not affect the DNA sequence of genes, but change how the DNA is packaged and how genes are expressed.

Types of cancer are no longer divided up and treated according to the origin of the tissue; instead, targeted analyses (such as the sequencing of genes or examination for the presence of certain proteins) are carried out to detect individual mutations that can be exploited in the therapy.

The Dutch test uses the polymerase chain reaction to amplify the DNA sequence of the gene and adds a short modified sequence of nucleotides in front of it.

«Changes in genes» regulation — not in the DNA sequence of genes themselves — were the driving force behind successful metastases in our experiments, and, as far as we know, this is the first genomewide experimental evidence for this phenomenon.»

Researchers report that one tiny variation in the sequence of a gene may cause some people to be more impaired by traumatic brain injury (TBI) than others with comparable wounds.

They identified 24 previously unknown epigenetic changes that alter a woman's risk of breast cancer and can be passed down through generations without involving changes in the DNA sequence of genes.

cDNA lacks the non-coding «introns» found in the full sequence of a gene.

In brown bears, the sequence of this gene varies from one bear to another, but all the polar bears surveyed have an identical version, with the exact same genetic code at nine variable spots in the gene, about half of which should change the function of the APOB protein.

«It shows how environmental factors can alter the genome without changing the sequences of genes, but by altering how the genome is regulated,» she says.